MPD: Project measures / variables set: Harrill2 urine

Project measures / variables set: Harrill2 urine_KIM1

ID, description, units	MPD:44135 urine_KIM1 urine kidney injury molecule 1 (KIM-1) [pg] DB289 study
Measures	• control • DB289 • difference
Data set, strains	Harrill2 inbred 33 strains sex: f age: 6-8wks
Procedure	biomarker quantification
Comparison	control group vs. treated group
Ontology mappings	VT:0001757 urine molecular composition trait VT:0010487 response to xenobiotic stimulus trait MA:0002545 urine MP:0006315 abnormal urine protein level MP:0008872 abnormal physiological response to xenobiotic

Values Means Δ Means Z-scores

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Harrill2 - urine kidney injury molecule 1 (KIM-1)

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	166202306.3911	166202306.3911	99.3096	< 0.0001
strain	29	822439498.2484	28359982.6982	16.9457	< 0.0001
group:strain	29	246918871.3605	8514443.84	5.0876	< 0.0001
Residuals	216	361492843.0833	1673577.9772

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Harrill2	44135	biomarker quantification	DB289	urine kidney injury molecule 1 (KIM-1) [pg] control urine_KIM1_ctrl	inbred	32	f	6-8wks
Harrill2	44136	biomarker quantification	DB289	urine kidney injury molecule 1 (KIM-1) [pg] DB289 urine_KIM1_trt	inbred	32	f	6-8wks
Harrill2	44235	biomarker quantification	DB289	urine kidney injury molecule 1 (KIM-1) [pg] difference urine_KIM1_fold	inbred	31	f	6-8wks	(supplemental / summary measure)