Project measure / variable:   Harrill2   urine_KIM1_trt

ID, description, units MPD:44136   urine_KIM1_trt   urine kidney injury molecule 1 (KIM-1)   [pg]  DB289  
DB289 study
Data set, strains Harrill2   inbred   32 strains     sex: f     age: 6-8wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Harrill2 - urine kidney injury molecule 1 (KIM-1) DB289



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested32 strains
Mean of the strain means2368   pg
Median of the strain means1312   pg
SD of the strain means± 2522
Coefficient of variation (CV)1.06
Min–max range of strain means54.0   –   8769   pg
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 30 906984168.5375 30232805.6179 11.9665 < 0.0001
Residuals 113 285488376.9 2526445.8133


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2252.0 1200.0   5 537.0 0.533 1014.0, 3928.0 -0.05
A/J f 1853.0 1834.0   5 820.0 0.989 323.0, 4185.0 -0.2
AKR/J f 115.0 58.0   5 25.9 0.503 46.0, 175.0 -0.89
BALB/cByJ f 7650.0 2462.0   5 1101.0 0.322 5262.0, 11329.0 2.09
BTBR T+ Itpr3tf/J f 2178.0 1456.0   5 651.0 0.668 601.0, 3927.0 -0.08
BUB/BnJ f 178.0 80.1   5 35.8 0.449 97.0, 299.0 -0.87
C3H/HeJ f 3668.0 2391.0   5 1069.0 0.652 1272.0, 6692.0 0.52
C57BL/6J f 1111.0 883.0   5 395.0 0.795 261.0, 2243.0 -0.5
C57BLKS/J f 945.0 183.0   3 106.0 0.194 757.0, 1123.0 -0.56
C57BR/cdJ f 278.0 278.0   4 139.0 1.0 51.0, 681.0 -0.83
CBA/J f 1225.0 1767.0   5 790.0 1.44 232.0, 4370.0 -0.45
CE/J f 1858.0 934.0   5 418.0 0.503 804.0, 3369.0 -0.2
DBA/2J f 1273.0 427.0   5 191.0 0.336 750.0, 1830.0 -0.43
FVB/NJ f 245.0 59.2   5 26.5 0.241 190.0, 346.0 -0.84
I/LnJ f 4732.0 2949.0   3 1702.0 0.623 2535.0, 8083.0 0.94
KK/HlJ f 8769.0 3267.0   5 1461.0 0.373 5214.0, 13661.0 2.54
LG/J f 3864.0 926.0   5 414.0 0.24 2774.0, 4911.0 0.59
LP/J f 476.0 299.0   5 134.0 0.629 163.0, 794.0 -0.75
MA/MyJ f 1352.0 1312.0   5 587.0 0.97 259.0, 3554.0 -0.4
MRL/MpJ f 4931.0 2047.0   5 915.0 0.415 1861.0, 6689.0 1.02
NOD/ShiLtJ f 92.7 44.6   3 25.8 0.482 53.0, 141.0 -0.9
NON/ShiLtJ f 5568.0 1880.0   4 940.0 0.338 3923.0, 8263.0 1.27
NOR/LtJ f 695.0 480.0   5 215.0 0.69 216.0, 1384.0 -0.66
NZW/LacJ f 4894.0 1248.0   5 558.0 0.255 3649.0, 6624.0 1.0
PL/J f 1811.0 934.0   5 418.0 0.516 387.0, 2819.0 -0.22
PWK/PhJ f 218.0 104.0   4 52.1 0.478 89.0, 322.0 -0.85
RIIIS/J f 1078.0 622.0   5 278.0 0.577 605.0, 2140.0 -0.51
SEA/GnJ f 304.0 0.0   1   0.0 0.0 304.0, 304.0 -0.82
SJL/J f 8201.0 3945.0   5 1764.0 0.481 4037.0, 12634.0 2.31
SM/J f 3834.0 2117.0   5 947.0 0.552 1295.0, 5953.0 0.58
SWR/J f 86.3 28.3   3 16.3 0.328 69.0, 119.0 -0.9
WSB/EiJ f 54.0 34.9   5 15.6 0.647 21.0, 110.0 -0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2252.2 710.8369 3660.4962 843.9038
A/J f 1853.2 710.8369 3261.4962 444.9038
AKR/J f 115.2 710.8369 1523.4962 0.0
BALB/cByJ f 7649.6 710.8369 9057.8962 6241.3038
BTBR T+ Itpr3tf/J f 2178.4 710.8369 3586.6962 770.1038
BUB/BnJ f 178.4 710.8369 1586.6962 0.0
C3H/HeJ f 3667.8 710.8369 5076.0962 2259.5038
C57BL/6J f 1111.0 710.8369 2519.2962 0.0
C57BLKS/J f 945.0 917.6866 2763.1026 0.0
C57BR/cdJ f 277.5 794.7399 1852.023 0.0
CBA/J f 1224.6 710.8369 2632.8962 0.0
CE/J f 1857.6 710.8369 3265.8962 449.3038
DBA/2J f 1273.0 710.8369 2681.2962 0.0
FVB/NJ f 245.4 710.8369 1653.6962 0.0
I/LnJ f 4731.6667 917.6866 6549.7692 2913.5641
KK/HlJ f 8769.0 710.8369 10177.2962 7360.7038
LG/J f 3864.2 710.8369 5272.4962 2455.9038
LP/J f 475.8 710.8369 1884.0962 0.0
MA/MyJ f 1352.4 710.8369 2760.6962 0.0
MRL/MpJ f 4931.4 710.8369 6339.6962 3523.1038
NOD/ShiLtJ f 92.6667 917.6866 1910.7692 0.0
NON/ShiLtJ f 5568.25 794.7399 7142.773 3993.727
NOR/LtJ f 695.0 710.8369 2103.2962 0.0
NZW/LacJ f 4894.0 710.8369 6302.2962 3485.7038
PL/J f 1810.6 710.8369 3218.8962 402.3038
PWK/PhJ f 217.75 794.7399 1792.273 0.0
RIIIS/J f 1078.0 710.8369 2486.2962 0.0
SJL/J f 8200.8 710.8369 9609.0962 6792.5038
SM/J f 3834.0 710.8369 5242.2962 2425.7038
SWR/J f 86.3333 917.6866 1904.4359 0.0
WSB/EiJ f 54.0 710.8369 1462.2962 0.0




  GWAS USING LINEAR MIXED MODELS