Project measure / variable:   Harrill2   urine_KIM1_ctrl

ID, description, units MPD:44135   urine_KIM1_ctrl   urine kidney injury molecule 1 (KIM-1)   [pg]  control  
DB289 study
Data set, strains Harrill2   inbred   32 strains     sex: f     age: 6-8wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Harrill2 - urine kidney injury molecule 1 (KIM-1) control



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested32 strains
Mean of the strain means896   pg
Median of the strain means374   pg
SD of the strain means± 1141
Coefficient of variation (CV)1.27
Min–max range of strain means24.2   –   3756   pg
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 30 182828891.3022 6094296.3767 8.579 < 0.0001
Residuals 107 76009952.85 710373.3911


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 481.0 396.0   5 177.0 0.823 188.0, 1133.0 -0.36
A/J f 244.0 146.0   5 65.3 0.598 27.0, 387.0 -0.57
AKR/J f 3756.0 3686.0   4 1843.0 0.981 33.0, 7514.0 2.51
BALB/cByJ f 3508.0 1230.0   5 550.0 0.351 1828.0, 4992.0 2.29
BTBR T+ Itpr3tf/J f 378.0 105.0   5 47.0 0.278 261.0, 509.0 -0.45
BUB/BnJ f 161.0 167.0   3 96.5 1.04 27.0, 348.0 -0.64
C3H/HeJ f 371.0 191.0   5 85.3 0.515 214.0, 699.0 -0.46
C57BL/6J f 115.0 51.2   3 29.6 0.444 67.0, 169.0 -0.68
C57BLKS/J f 167.0 131.0   5 58.4 0.78 50.0, 369.0 -0.64
C57BR/cdJ f 516.0 426.0   2   301.0 0.825 215.0, 817.0 -0.33
C58/J f 31.0 27.4   3 15.8 0.884 10.0, 62.0 -0.76
CBA/J f 124.0 76.2   5 34.1 0.612 69.0, 247.0 -0.68
CE/J f 112.0 43.3   5 19.3 0.388 50.0, 165.0 -0.69
DBA/2J f 291.0 163.0   5 72.7 0.558 107.0, 433.0 -0.53
FVB/NJ f 196.0 48.6   5 21.7 0.248 141.0, 249.0 -0.61
I/LnJ f 1535.0 1222.0   5 547.0 0.796 461.0, 3605.0 0.56
KK/HlJ f 3372.0 431.0   5 193.0 0.128 2939.0, 4037.0 2.17
LG/J f 862.0 381.0   5 171.0 0.442 212.0, 1159.0 -0.03
LP/J f 306.0 241.0   5 108.0 0.788 45.0, 640.0 -0.52
MA/MyJ f 538.0 789.0   3 456.0 1.47 59.0, 1449.0 -0.31
MRL/MpJ f 1068.0 570.0   5 255.0 0.533 418.0, 1633.0 0.15
NOD/ShiLtJ f 294.0 0.0   1   0.0 0.0 294.0, 294.0 -0.53
NON/ShiLtJ f 1133.0 515.0   5 231.0 0.455 392.0, 1681.0 0.21
NOR/LtJ f 789.0 532.0   5 238.0 0.674 383.0, 1708.0 -0.09
NZW/LacJ f 3194.0 1357.0   5 607.0 0.425 2008.0, 5514.0 2.01
PL/J f 989.0 474.0   5 212.0 0.479 507.0, 1644.0 0.08
PWK/PhJ f 72.5 24.7   2   17.5 0.341 55.0, 90.0 -0.72
RIIIS/J f 253.0 142.0   5 63.5 0.561 127.0, 487.0 -0.56
SJL/J f 2948.0 985.0   5 440.0 0.334 1529.0, 4057.0 1.8
SM/J f 790.0 915.0   5 409.0 1.16 205.0, 2409.0 -0.09
SWR/J f 51.0 13.7   4 6.86 0.269 38.0, 68.0 -0.74
WSB/EiJ f 24.2 21.8   4 10.9 0.899 2.0, 52.0 -0.76


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 481.2 376.9279 1228.4157 0.0
A/J f 244.4 376.9279 991.6157 0.0
AKR/J f 3756.0 421.4183 4591.4125 2920.5875
BALB/cByJ f 3508.4 376.9279 4255.6157 2761.1843
BTBR T+ Itpr3tf/J f 378.2 376.9279 1125.4157 0.0
BUB/BnJ f 160.6667 486.6119 1125.318 0.0
C3H/HeJ f 370.8 376.9279 1118.0157 0.0
C57BL/6J f 115.3333 486.6119 1079.9846 0.0
C57BLKS/J f 167.4 376.9279 914.6157 0.0
C57BR/cdJ f 516.0 595.9754 1697.4518 0.0
C58/J f 31.0 486.6119 995.6513 0.0
CBA/J f 124.4 376.9279 871.6157 0.0
CE/J f 111.6 376.9279 858.8157 0.0
DBA/2J f 291.2 376.9279 1038.4157 0.0
FVB/NJ f 195.8 376.9279 943.0157 0.0
I/LnJ f 1535.2 376.9279 2282.4157 787.9843
KK/HlJ f 3372.0 376.9279 4119.2157 2624.7843
LG/J f 862.4 376.9279 1609.6157 115.1843
LP/J f 306.2 376.9279 1053.4157 0.0
MA/MyJ f 538.3333 486.6119 1502.9846 0.0
MRL/MpJ f 1067.8 376.9279 1815.0157 320.5843
NON/ShiLtJ f 1133.0 376.9279 1880.2157 385.7843
NOR/LtJ f 788.8 376.9279 1536.0157 41.5843
NZW/LacJ f 3194.0 376.9279 3941.2157 2446.7843
PL/J f 988.6 376.9279 1735.8157 241.3843
PWK/PhJ f 72.5 595.9754 1253.9518 0.0
RIIIS/J f 253.0 376.9279 1000.2157 0.0
SJL/J f 2947.8 376.9279 3695.0157 2200.5843
SM/J f 790.4 376.9279 1537.6157 43.1843
SWR/J f 51.0 421.4183 886.4125 0.0
WSB/EiJ f 24.25 421.4183 859.6625 0.0




  GWAS USING LINEAR MIXED MODELS