MPD: Project measures / variables set: Maurer1 heart

Project measures / variables set: Maurer1 heart_wt

ID, description, units	MPD:33270 heart_wt heart weight [mg] atenolol, isoproterenol study
Measures	• control • atenolol 10mg • isoprot 1mg • isoprot 10mg
Data set, strains	Maurer1 inbred 23 strains sex: m age: 7-13wks
Procedure	organ weights
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0007028 heart mass VT:0010487 response to xenobiotic stimulus trait MA:0000072 heart MP:0004857 abnormal heart weight MP:0008872 abnormal physiological response to xenobiotic

Values Means Δ Means Z-scores

Graph Type Points Bars

Dimensions Width: × Height: px

Plot Options Hide Error Bars Strains on X-axis

Strains

measured value [mg]

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	3	85377.3273	28459.1091	290.2008	< 0.0001
strain	22	211242.9922	9601.9542	97.9122	< 0.0001
group:strain	66	19323.2844	292.777	2.9855	< 0.0001
Residuals	873	85612.4538	98.067

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Maurer1	33270	organ weights	atenolol, isoproterenol	heart weight [mg] control heart_wt_ctrl	inbred	23	m	7-13wks
Maurer1	33271	organ weights	atenolol, isoproterenol	heart weight [mg] atenolol 10mg heart_wt_at	inbred	23	m	7-13wks
Maurer1	33272	organ weights	atenolol, isoproterenol	heart weight [mg] isoprot 1mg heart_wt_iso1	inbred	23	m	7-13wks
Maurer1	33273	organ weights	atenolol, isoproterenol	heart weight [mg] isoprot 10mg heart_wt_iso10	inbred	23	m	7-13wks