Project measure / variable:   Maurer1   heart_wt_at

ID, description, units MPD:33271   heart_wt_at   heart weight   [mg]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Maurer1 - heart weight atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means100   mg
Median of the strain means98.4   mg
SD of the strain means± 15.5
Coefficient of variation (CV)0.155
Min–max range of strain means69.6   –   127   mg
Mean sample size per strain10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 54624.775 2482.9443 31.3995 < 0.0001
Residuals 217 17159.4715 79.0759


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 99.0 10.3   13 2.86 0.104 81.5, 117.0 -0.08
A/J m 69.6 6.96   10 2.2 0.1 58.8, 83.8 -1.98
AKR/J m 120.0 12.6   9 4.21 0.106 101.0, 147.0 1.27
BALB/cByJ m 124.0 10.2   16 2.55 0.0825 110.0, 148.0 1.53
BALB/cJ m 98.4 9.46   10 2.99 0.0961 85.9, 122.0 -0.12
BTBR T+ Itpr3tf/J m 127.0 9.07   9 3.02 0.0717 111.0, 140.0 1.72
C3H/HeJ m 92.8 8.5   10 2.69 0.0916 82.7, 106.0 -0.48
C3H/HeOuJ m 91.8 6.71   10 2.12 0.0731 82.8, 104.0 -0.55
C57BL/6J m 89.7 7.57   9 2.52 0.0844 80.9, 107.0 -0.68
C57BLKS/J m 88.7 7.03   9 2.34 0.0793 73.3, 98.2 -0.75
C58/J m 88.9 9.03   12 2.61 0.102 77.0, 103.0 -0.74
CBA/J m 93.6 6.94   9 2.31 0.0742 79.4, 102.0 -0.43
DBA/2J m 110.0 6.31   10 2.0 0.0574 96.9, 118.0 0.63
FVB/NJ m 104.0 6.69   14 1.79 0.0646 92.6, 114.0 0.24
I/LnJ m 106.0 12.8   10 4.06 0.121 91.1, 128.0 0.37
KK/HlJ m 122.0 8.9   9 2.97 0.0727 108.0, 135.0 1.4
LP/J m 87.8 12.6   10 3.97 0.143 73.7, 109.0 -0.81
NOD/ShiLtJ m 99.5 8.95   10 2.83 0.0899 86.1, 113.0 -0.05
NZB/BlNJ m 120.0 6.67   9 2.22 0.0555 109.0, 132.0 1.27
PL/J m 117.0 11.0   10 3.47 0.0937 97.7, 138.0 1.08
SJL/J m 91.7 3.82   9 1.27 0.0416 86.9, 96.9 -0.56
SM/J m 83.3 8.92   12 2.58 0.107 72.7, 102.0 -1.1
SWR/J m 82.2 5.71   11 1.72 0.0694 75.0, 92.5 -1.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 99.0308 2.4663 103.8918 94.1697
A/J m 69.64 2.812 75.1824 64.0976
AKR/J m 119.5556 2.9642 125.3978 113.7133
BALB/cByJ m 123.5625 2.2231 127.9442 119.1808
BALB/cJ m 98.44 2.812 103.9824 92.8976
BTBR T+ Itpr3tf/J m 126.5556 2.9642 132.3978 120.7133
C3H/HeJ m 92.79 2.812 98.3324 87.2476
C3H/HeOuJ m 91.76 2.812 97.3024 86.2176
C57BL/6J m 89.6667 2.9642 95.5089 83.8244
C57BLKS/J m 88.7111 2.9642 94.5533 82.8689
C58/J m 88.925 2.567 93.9845 83.8655
CBA/J m 93.6111 2.9642 99.4533 87.7689
DBA/2J m 109.99 2.812 115.5324 104.4476
FVB/NJ m 103.6143 2.3766 108.2985 98.9301
I/LnJ m 106.08 2.812 111.6224 100.5376
KK/HlJ m 122.4444 2.9642 128.2867 116.6022
LP/J m 87.78 2.812 93.3224 82.2376
NOD/ShiLtJ m 99.55 2.812 105.0924 94.0076
NZB/BlNJ m 120.2222 2.9642 126.0644 114.38
PL/J m 116.97 2.812 122.5124 111.4276
SJL/J m 91.6889 2.9642 97.5311 85.8467
SM/J m 83.275 2.567 88.3345 78.2155
SWR/J m 82.2455 2.6812 87.5299 76.961




  GWAS USING LINEAR MIXED MODELS