MPD: Project measures / variables set: Mills1 RBC

Project measures / variables set: Mills1 RBC_micronucl

ID, description, units	MPD:25231 RBC_micronucl red blood cells (RBC) with micronuclei [%]
Measures	• 6mo • 12mo • 20mo
Data set, strains	Mills1 inbred 30 strains sex: both
Procedure	chromosome instability assessment
Comparison	aging-study, multiple cohorts
Ontology mappings	VT:0002447 erythrocyte morphology trait MA:0000059 blood MP:0002447 abnormal erythrocyte morphology MP:0008866 chromosomal instability

Values Means Δ Means Z-scores

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Mills1 - red blood cells (RBC) with micronuclei

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	2	0.2087	0.1044	12.9319	< 0.0001
sex	1	0.9613	0.9613	119.1053	< 0.0001
strain	1	0.4814	0.4814	59.6471	< 0.0001
age:sex	2	0.169	0.0845	10.4684	0.0002
age:strain	2	0.0032	0.0016	0.201	0.8186
sex:strain	1	0.2265	0.2265	28.0628	< 0.0001
age:sex:strain	2	0.0112	0.0056	0.6913	0.5057
Residuals	50	0.4035	0.0081

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Mills1	25231	chromosome instability assessment	(none)	red blood cells (RBC) with micronuclei [%] at age 6mo RBC_micronucl_M06	inbred	7	both	26wks
Mills1	25232	chromosome instability assessment	(none)	red blood cells (RBC) with micronuclei [%] at age 12mo RBC_micronucl_M12	inbred	30	both	52wks
Mills1	25233	chromosome instability assessment	(none)	red blood cells (RBC) with micronuclei [%] at age 20mo RBC_micronucl_M20	inbred	25	both	87wks