MPD: Project measures / variables set: Graubert1 lymphoid

Project measures / variables set: Graubert1 lymphoid_tumor

ID, description, units	MPD:11618 lymphoid_tumor lymphoid tumor frequency rate [score] ENU study
Measures	• control • ENU
Data set, strains	Graubert1 inbred 20 strains sex: both age: 13-68wks
Procedure	histopathology
Comparison	control group vs. treated group
Ontology mappings	VT:0010252 hemolymphoid system morphology trait VT:0010487 response to xenobiotic stimulus trait MA:0002436 lymphoid tissue MP:0008872 abnormal physiological response to xenobiotic MP:0010639 altered tumor pathology MP:0013151 abnormal incidence of induced tumors

Values Means Δ Means Z-scores

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Graubert1 - lymphoid tumor frequency rate

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	3.4309	3.4309	50.2269	< 0.0001
sex	1	0.1436	0.1436	2.102	0.148
strain	18	6.2003	0.3445	5.0428	< 0.0001
group:sex	1	0.0202	0.0202	0.2962	0.5866
group:strain	18	3.4662	0.1926	2.8191	0.0001
sex:strain	18	1.8365	0.102	1.4936	0.0886
group:sex:strain	18	1.5039	0.0836	1.2232	0.2389
Residuals	373	25.4786	0.0683

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Graubert1	11618	histopathology	ENU	lymphoid tumor frequency rate [score] control lymphoid_tumor	inbred	20	both	13-68wks
Graubert1	11658	histopathology	ENU	lymphoid tumor frequency rate [score] ENU lymphoid_tumor_enu	inbred	20	both	13-68wks