Project measure / variable:   Schwartz2   pctEOS_ova24

ID, description, units MPD:9807   pctEOS_ova24   alveolar eosinophils (percentage of total lavage cells), 24h post-challenge   [%]  OVA-sensitized  
ovalbumin study
Data set, strains Schwartz2   inbred   8 strains     sex: m     age: 6-8wks
Procedure bronchoalveolar lavage assessment
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  STRAIN COMPARISON PLOT
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Schwartz2 - alveolar eosinophils (percentage of total lavage cells), 24h post-challenge OVA-sensitized



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means22.2   %
Median of the strain means15.4   %
SD of the strain means± 13.6
Coefficient of variation (CV)0.611
Min–max range of strain means8.60   –   47.4   %
Mean sample size per strain5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 6430.175 918.5964 2.8827 0.0188
Residuals 32 10197.1 318.6594


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 47.4 34.2   5 15.3 0.722 9.0, 80.0 1.86
A/J m 36.6 17.3   5 7.76 0.474 12.0, 54.0 1.06
BALB/cJ m 14.8 13.8   5 6.18 0.934 -0.54
BTBR T+ Itpr3tf/J m 12.8 9.34   5 4.18 0.73 1.0, 25.0 -0.69
C3H/HeJ m 16.0 16.2   5 7.24 1.01 -0.46
C57BL/6J m 14.6 7.16   5 3.2 0.491 8.0, 25.0 -0.56
DBA/2J m 26.6 20.1   5 9.0 0.756 4.0, 55.0 0.33
FVB/NJ m 8.6 8.99   5 4.02 1.05 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 47.4 7.9832 63.6613 31.1387
A/J m 36.6 7.9832 52.8613 20.3387
BALB/cJ m 14.8 7.9832 31.0613 0.0
BTBR T+ Itpr3tf/J m 12.8 7.9832 29.0613 0.0
C3H/HeJ m 16.0 7.9832 32.2613 0.0
C57BL/6J m 14.6 7.9832 30.8613 0.0
DBA/2J m 26.6 7.9832 42.8613 10.3387
FVB/NJ m 8.6 7.9832 24.8613 0.0




  GWAS USING LINEAR MIXED MODELS