Phenotype measure:   Brown1   defecation_EZM


  STRAIN COMPARISON PLOT
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Brown1 - fecal boli count



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains13 strains
Mean of the strain means2.29   n 2.79   n
Median of the strain means2.17   n 2.33   n
SD of the strain means± 1.96 ± 1.85
Coefficient of variation (CV)0.856 0.663
Min–max range of strain means0   –   6.58   n 0.250   –   6.92   n
Mean sample size per strain10.0   mice 7.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8206 0.8206 0.1464 0.7025
strain 9 723.875 80.4306 14.3475 < 0.0001
sex:strain 9 68.1707 7.5745 1.3512 0.2143
Residuals 168 941.788 5.6059


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.2 1.81   10 0.573 0.567 2.0, 8.0 0.46
129S1/SvImJ m 2.3 2.58   10 0.817 1.12 -0.27
A/J f 6.58 3.37   12 0.973 0.512 1.0, 11.0 2.19
A/J m 5.0 3.58   6 1.46 0.716 1.0, 10.0 1.19
AKR/J f 2.5 2.75   12 0.793 1.1 0.11
AKR/J m 3.33 3.01   6 1.23 0.903 1.0, 9.0 0.29
BALB/cByJ f 4.41 3.22   22 0.686 0.73 1.08
BALB/cByJ m 6.92 3.12   12 0.9 0.451 2.0, 12.0 2.23
BALB/cJ f 2.86 1.79   14 0.479 0.627 0.29
BALB/cJ m 4.1 2.13   10 0.674 0.52 2.0, 8.0 0.71
C57BL/6J f 0.0 0.0   10 0.0 0.0 -1.17
C57BL/6J m 1.56 1.59   9 0.53 1.02 -0.67
CAST/EiJ f 1.0 1.41   2   1.0 1.41 -0.66
CAST/EiJ m 0.25 0.5   4 0.25 2.0 -1.37
DBA/2J f 1.0 1.1   6 0.447 1.1 -0.66
DBA/2J m 1.8 2.57   10 0.814 1.43 -0.54
FVB/NJ f 0.0833 0.289   12 0.0833 3.46 -1.13
FVB/NJ m 0.5 0.905   12 0.261 1.81 -1.24
MOLF/EiJ m 3.7 0.949   10 0.3 0.256 2.0, 5.0 0.49
SJL/J f 2.17 2.04   6 0.833 0.942 -0.06
SJL/J m 2.33 2.08   3 1.2 0.892 -0.25
SM/J m 1.5 1.76   6 0.719 1.17 -0.7
SPRET/EiJ f 1.38 1.19   8 0.42 0.864 -0.46
SPRET/EiJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 0.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.2 0.7487 4.6781 1.7219
129S1/SvImJ m 2.3 0.7487 3.7781 0.8219
A/J f 6.5833 0.6835 7.9327 5.234
A/J m 5.0 0.9666 6.9082 3.0918
AKR/J f 2.5 0.6835 3.8493 1.1507
AKR/J m 3.3333 0.9666 5.2416 1.4251
BALB/cByJ f 4.4091 0.5048 5.4056 3.4125
BALB/cByJ m 6.9167 0.6835 8.266 5.5673
BALB/cJ f 2.8571 0.6328 4.1064 1.6079
BALB/cJ m 4.1 0.7487 5.5781 2.6219
C57BL/6J f 0.0 0.7487 1.4781 -1.4781
C57BL/6J m 1.5556 0.7892 3.1136 -0.0025
CAST/EiJ f 1.0 1.6742 4.3052 -2.3052
CAST/EiJ m 0.25 1.1838 2.5871 -2.0871
DBA/2J f 1.0 0.9666 2.9082 -0.9082
DBA/2J m 1.8 0.7487 3.2781 0.3219
FVB/NJ f 0.0833 0.6835 1.4327 -1.266
FVB/NJ m 0.5 0.6835 1.8493 -0.8493
SJL/J f 2.1667 0.9666 4.0749 0.2584
SJL/J m 2.3333 1.367 5.032 -0.3653


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.75 0.5294 3.7952 1.7048
A/J both 5.7917 0.5919 6.9602 4.6231
AKR/J both 2.9167 0.5919 4.0852 1.7481
BALB/cByJ both 5.6629 0.4248 6.5016 4.8242
BALB/cJ both 3.4786 0.4902 4.4462 2.5109
C57BL/6J both 0.7778 0.5439 1.8516 -0.2961
CAST/EiJ both 0.625 1.0252 2.649 -1.399
DBA/2J both 1.4 0.6113 2.6069 0.1931
FVB/NJ both 0.2917 0.4833 1.2458 -0.6625
SJL/J both 2.25 0.8371 3.9026 0.5974




  GWAS USING LINEAR MIXED MODELS