Phenotype measure:   Brown1   activity_EZM


  STRAIN COMPARISON PLOT
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Brown1 - total activity, line crosses plus rearing, 5 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains13 strains
Mean of the strain means39.8   n 43.5   n
Median of the strain means38.5   n 49.3   n
SD of the strain means± 19.0 ± 17.2
Coefficient of variation (CV)0.478 0.395
Min–max range of strain means11.2   –   71.4   n 15.0   –   70.8   n
Mean sample size per strain10.1   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 773.3183 773.3183 1.7998 0.1815
strain 9 40370.4405 4485.6045 10.4399 < 0.0001
sex:strain 9 8472.0906 941.3434 2.1909 0.0249
Residuals 170 73042.4665 429.6616


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 18.9 12.4   10 3.94 0.659 4.0, 41.0 -1.1
129S1/SvImJ m 26.2 17.8   10 5.63 0.68 3.0, 57.0 -1.01
A/J f 23.4 25.7   12 7.41 1.1 -0.86
A/J m 15.2 9.54   6 3.89 0.629 4.0, 28.0 -1.65
AKR/J f 56.7 21.3   12 6.16 0.376 32.0, 94.0 0.89
AKR/J m 36.7 5.28   6 2.16 0.144 28.0, 44.0 -0.4
BALB/cByJ f 38.5 23.7   22 5.06 0.616 2.0, 80.0 -0.07
BALB/cByJ m 50.8 32.4   12 9.34 0.638 9.0, 125.0 0.42
BALB/cJ f 36.9 22.1   14 5.91 0.599 9.0, 92.0 -0.15
BALB/cJ m 65.4 26.9   10 8.51 0.411 29.0, 111.0 1.27
C57BL/6J f 46.3 7.86   10 2.49 0.17 31.0, 56.0 0.34
C57BL/6J m 39.9 13.8   10 4.37 0.346 23.0, 62.0 -0.21
CAST/EiJ f 27.0 8.49   2   6.0 0.314 21.0, 33.0 -0.67
CAST/EiJ m 40.0 17.9   5 8.02 0.448 20.0, 69.0 -0.2
DBA/2J f 43.7 16.0   6 6.54 0.367 25.0, 63.0 0.2
DBA/2J m 50.2 12.8   10 4.04 0.255 24.0, 73.0 0.39
FVB/NJ f 71.4 16.8   12 4.86 0.236 48.0, 93.0 1.66
FVB/NJ m 70.8 13.5   12 3.9 0.191 49.0, 97.0 1.59
MOLF/EiJ m 56.6 16.5   10 5.22 0.292 33.0, 82.0 0.76
SJL/J f 64.0 40.5   6 16.5 0.632 1.0, 106.0 1.27
SJL/J m 49.3 4.62   3 2.67 0.0936 44.0, 52.0 0.34
SM/J m 49.7 31.9   6 13.0 0.642 14.0, 98.0 0.36
SPRET/EiJ f 11.2 7.28   9 2.43 0.648 2.0, 20.0 -1.5
SPRET/EiJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -1.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 18.9 6.5549 31.8394 5.9606
129S1/SvImJ m 26.2 6.5549 39.1394 13.2606
A/J f 23.4167 5.9837 35.2287 11.6047
A/J m 15.1667 8.4623 31.8714 0.0
AKR/J f 56.6667 5.9837 68.4787 44.8547
AKR/J m 36.6667 8.4623 53.3714 19.962
BALB/cByJ f 38.5455 4.4193 47.2692 29.8217
BALB/cByJ m 50.75 5.9837 62.562 38.938
BALB/cJ f 36.9286 5.5399 47.8644 25.9928
BALB/cJ m 65.4 6.5549 78.3394 52.4606
C57BL/6J f 46.3 6.5549 59.2394 33.3606
C57BL/6J m 39.9 6.5549 52.8394 26.9606
CAST/EiJ f 27.0 14.6571 55.9334 0.0
CAST/EiJ m 40.0 9.27 58.2991 21.7009
DBA/2J f 43.6667 8.4623 60.3714 26.962
DBA/2J m 50.2 6.5549 63.1394 37.2606
FVB/NJ f 71.4167 5.9837 83.2287 59.6047
FVB/NJ m 70.8333 5.9837 82.6453 59.0213
SJL/J f 64.0 8.4623 80.7047 47.2953
SJL/J m 49.3333 11.9675 72.9573 25.7093


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 22.55 4.635 31.6995 13.4005
A/J both 19.2917 5.1821 29.5212 9.0622
AKR/J both 46.6667 5.1821 56.8962 36.4372
BALB/cByJ both 44.6477 3.7194 51.9898 37.3056
BALB/cJ both 51.1643 4.2912 59.6351 42.6935
C57BL/6J both 43.1 4.635 52.2495 33.9505
CAST/EiJ both 33.5 8.6713 50.6172 16.3828
DBA/2J both 46.9333 5.352 57.4983 36.3684
FVB/NJ both 71.125 4.2311 79.4773 62.7727
SJL/J both 56.6667 7.3286 71.1334 42.2




  GWAS USING LINEAR MIXED MODELS