Project measure / variable:   CSNA03   dist_l60_cocaine_in_d19

ID, description, units MPD:90433   dist_l60_cocaine_in_d19   distance traveled, last 60 min (post-injection), on successive days, cocaine sensitization, founders   [cm]  day 19  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
Ontology mappings

  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, last 60 min (post-injection), on successive days, cocaine sensitization, founders day 19



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means22740.0   cm 23970.0   cm
Median of the strain means20762.0   cm 28752.0   cm
SD of the strain means± 16654.0 ± 16057.0
Coefficient of variation (CV)0.7323 0.6699
Min–max range of strain means1455.0   –   50156.0   cm 2006.0   –   41218.0   cm
Mean sample size per strain6.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 39986584.1401 39986584.1401 0.3922 0.5325
strain 8 28283335787.2965 3535416973.4121 34.6804 < 0.0001
sex:strain 8 1991073125.5591 248884140.6949 2.4414 0.0183
Residuals 105 10703995090.0028 101942810.381


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8294.0 16181.0   6 6606.0 1.9509 -0.87
129S1/SvImJ m 2006.0 2410.0   6 984.0 1.2014 13.189, 6386.0 -1.37
A/J f 9564.0 18224.0   12 5261.0 1.9054 1059.0, 66693.0 -0.79
A/J m 3870.0 5456.0   12 1575.0 1.4097 38.185, 18999.0 -1.25
C57BL/6J f 20720.0 2269.0   5 1015.0 0.1095 17681.0, 23898.0 -0.12
C57BL/6J m 25207.0 5086.0   7 1922.0 0.2018 19919.0, 32995.0 0.08
C57BL/6NJ f 1455.0 0.0   1   0.0 0.0 1455.0, 1455.0 -1.28
C57BL/6NJ m 11831.0 0.0   1   0.0 0.0 11831.0, 11831.0 -0.76
CAST/EiJ f 48536.0 9067.0   6 3702.0 0.1868 39006.0, 59746.0 1.55
CAST/EiJ m 40775.0 14145.0   5 6326.0 0.3469 21444.0, 54151.0 1.05
DBA/2J f 20805.0 3073.0   3 1774.0 0.1477 17527.0, 23620.0 -0.12
DBA/2J m 36018.0 10786.0   4 5393.0 0.2995 27383.0, 50221.0 0.75
NOD/ShiLtJ f 27258.0 9998.0   6 4082.0 0.3668 16846.0, 40799.0 0.27
NOD/ShiLtJ m 32296.0 8519.0   6 3478.0 0.2638 19846.0, 44089.0 0.52
NZO/HlLtJ f 10217.0 3308.0   6 1351.0 0.3238 6374.0, 16109.0 -0.75
NZO/HlLtJ m 7590.0 4913.0   7 1857.0 0.6473 1455.0, 16536.0 -1.02
PWK/PhJ f 30395.0 5645.0   9 1882.0 0.1857 22277.0, 41423.0 0.46
PWK/PhJ m 41218.0 10256.0   9 3419.0 0.2488 28370.0, 60912.0 1.07
WSB/EiJ f 50156.0 11899.0   7 4497.0 0.2372 29645.0, 63141.0 1.65
WSB/EiJ m 38886.0 10180.0   7 3848.0 0.2618 26781.0, 56145.0 0.93


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8293.9666666667 4121.949586886 16467.0312653575 120.9020679759
129S1/SvImJ m 2006.1446666667 4121.949586886 10179.2092653575 -6166.9199320241
A/J f 9564.5 2914.6585045962 15343.72940081 3785.27059919
A/J m 3870.4320833334 2914.6585045962 9649.6614841433 -1908.7973174766
C57BL/6J f 20719.6 4515.3695392731 29672.7436892997 11766.4563107003
C57BL/6J m 25207.1428571429 3816.1837777882 32773.9303393503 17640.3553749355
CAST/EiJ f 48536.1666666666 4121.949586886 56709.2312653574 40363.1020679758
CAST/EiJ m 40775.1999999999 4515.3695392731 49728.3436892996 31822.0563107003
DBA/2J f 20804.6666666667 5829.3170091924 32363.1254682866 9246.2078650468
DBA/2J m 36018.5 5048.3366166733 46028.4189507987 26008.5810492013
NOD/ShiLtJ f 27258.3333333334 4121.949586886 35431.3979320241 19085.2687346426
NOD/ShiLtJ m 32296.3333333334 4121.949586886 40469.3979320242 24123.2687346426
NZO/HlLtJ f 10216.6666666667 4121.949586886 18389.7312653575 2043.602067976
NZO/HlLtJ m 7590.4285714285 3816.1837777882 15157.2160536359 23.6410892211
PWK/PhJ f 30395.0 3365.5577444489 37068.2793005324 23721.7206994675
PWK/PhJ m 41218.4444444445 3365.5577444489 47891.7237449769 34545.165143912
WSB/EiJ f 50155.7142857143 3816.1837777882 57722.5017679217 42588.9268035069
WSB/EiJ m 38886.1428571429 3816.1837777882 46452.9303393503 31319.3553749355


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5150.0556666667 2914.6585045962 10929.2850674767 -629.1737341433
A/J both 6717.4660416667 2060.974793443 10803.9983410121 2630.9337423213
C57BL/6J both 22963.3714285714 2956.0032434882 28824.5798091475 17102.1630479954
CAST/EiJ both 44655.6833333333 3056.9196290149 50716.9902645078 38594.3764021587
DBA/2J both 28411.5833333334 3855.7307799205 36056.7852154013 20766.3814512654
NOD/ShiLtJ both 29777.3333333334 2914.6585045962 35556.5627341433 23998.1039325234
NZO/HlLtJ both 8903.5476190476 2808.6352122821 14472.5524164792 3334.5428216161
PWK/PhJ both 35806.7222222222 2379.8087035747 40525.4432683805 31088.0011760639
WSB/EiJ both 44520.9285714286 2698.4494275282 49871.4553118949 39170.4018309622




  GWAS USING LINEAR MIXED MODELS