Project measure / variable:   CSNA03   dist_l60_cocaine_in_d11

ID, description, units MPD:90421   dist_l60_cocaine_in_d11   distance traveled, last 60 min (post-injection), on successive days, cocaine sensitization, founders   [cm]  day 11  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, last 60 min (post-injection), on successive days, cocaine sensitization, founders day 11



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means23698.0   cm 22173.0   cm
Median of the strain means20516.0   cm 26498.0   cm
SD of the strain means± 16432.0 ± 14121.0
Coefficient of variation (CV)0.6934 0.6369
Min–max range of strain means3299.0   –   54401.0   cm 1934.0   –   39690.0   cm
Mean sample size per strain6.0   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 298100375.7733 298100375.7733 1.8749 0.1739
strain 8 26212217569.0179 3276527196.1272 20.6077 < 0.0001
sex:strain 8 2796361223.3027 349545152.9128 2.1985 0.0333
Residuals 104 16535499718.9349 158995189.6051


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 15173.0 36807.0   6 15026.0 2.4258 -0.52
129S1/SvImJ m 1934.0 2005.0   6 818.6 1.037 94.13, 5711.0 -1.43
A/J f 3299.0 3013.0   11 908.5 0.9133 407.8, 10159.0 -1.24
A/J m 4524.0 4351.0   12 1256.0 0.9618 578.1, 15445.0 -1.25
C57BL/6J f 13779.0 7358.0   6 3004.0 0.534 -0.6
C57BL/6J m 24804.0 8716.0   7 3295.0 0.3514 14927.0, 38759.0 0.19
C57BL/6NJ f 6763.0 0.0   1   0.0 0.0 6763.0, 6763.0 -1.03
C57BL/6NJ m 12901.0 0.0   1   0.0 0.0 12901.0, 12901.0 -0.66
CAST/EiJ f 42466.0 16723.0   6 6827.0 0.3938 20951.0, 61007.0 1.14
CAST/EiJ m 39097.0 20761.0   5 9284.0 0.531 19564.0, 73504.0 1.2
DBA/2J f 25859.0 6767.0   3 3907.0 0.2617 18131.0, 30725.0 0.13
DBA/2J m 28193.0 10289.0   4 5145.0 0.365 15358.0, 38883.0 0.43
NOD/ShiLtJ f 27495.0 8521.0   6 3479.0 0.3099 16653.0, 39012.0 0.23
NOD/ShiLtJ m 30338.0 9752.0   6 3981.0 0.3215 16308.0, 44848.0 0.58
NZO/HlLtJ f 12876.0 4382.0   5 1960.0 0.3403 9199.0, 18905.0 -0.66
NZO/HlLtJ m 8374.0 3274.0   7 1238.0 0.391 2814.0, 13694.0 -0.98
PWK/PhJ f 34873.0 6543.0   9 2181.0 0.1876 23227.0, 42120.0 0.68
PWK/PhJ m 39690.0 14997.0   9 4999.0 0.3778 21548.0, 62088.0 1.24
WSB/EiJ f 54401.0 15466.0   7 5845.0 0.2843 36639.0, 82782.0 1.87
WSB/EiJ m 31873.0 10232.0   7 3867.0 0.321 21168.0, 47249.0 0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 15172.9166666667 5147.7371987626 25381.0727082891 4964.7606250443
129S1/SvImJ m 1933.5216666667 5147.7371987626 12141.6777082891 -8274.6343749557
A/J f 3299.2545454545 3801.8558817927 10838.4774293324 -4239.9683384233
A/J m 4524.1083333333 3639.9998810113 11742.3646937749 -2694.1480271083
C57BL/6J f 13779.3333333333 5147.7371987626 23987.4893749557 3571.177291711
C57BL/6J m 24804.0 4765.8785669612 34254.9160449486 15353.0839550514
CAST/EiJ f 42466.1666666666 5147.7371987626 52674.322708289 32258.0106250442
CAST/EiJ m 39097.0 5639.0635677414 50279.4746690584 27914.5253309415
DBA/2J f 25858.6666666666 7279.9997620225 40295.1793875499 11422.1539457834
DBA/2J m 28193.0 6304.6647334562 40695.3867583421 15690.613241658
NOD/ShiLtJ f 27494.6666666666 5147.7371987626 37702.822708289 17286.5106250443
NOD/ShiLtJ m 30337.6666666666 5147.7371987626 40545.822708289 20129.5106250443
NZO/HlLtJ f 12875.8 5639.0635677414 24058.2746690584 1693.3253309416
NZO/HlLtJ m 8374.2857142857 4765.8785669612 17825.2017592343 -1076.6303306629
PWK/PhJ f 34873.1111111111 4203.1098223041 43208.0356166725 26538.1866055497
PWK/PhJ m 39690.3333333333 4203.1098223041 48025.2578388947 31355.408827772
WSB/EiJ f 54401.0 4765.8785669612 63851.9160449486 44950.0839550514
WSB/EiJ m 31872.7142857143 4765.8785669612 41323.6303306629 22421.7982407657


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8553.2191666667 3639.9998810113 15771.4755271083 1334.9628062251
A/J both 3911.6814393939 2631.7155659229 9130.4721656504 -1307.1092868626
C57BL/6J both 19291.6666666667 3507.5916517799 26247.3525397273 12335.9807936061
CAST/EiJ both 40781.5833333333 3817.6640825429 48352.1544725249 33211.0121941417
DBA/2J both 27025.8333333333 4815.2672287302 36574.6889479527 17476.977718714
NOD/ShiLtJ both 28916.1666666666 3639.9998810112 36134.4230271082 21697.910306225
NZO/HlLtJ both 10625.0428571428 3691.6336639775 17945.6909468409 3304.3947674448
PWK/PhJ both 37281.7222222222 2972.047457423 43175.4038607826 31388.0405836618
WSB/EiJ both 43136.8571428571 3369.9850530099 49819.663966665 36454.0503190492




  GWAS USING LINEAR MIXED MODELS