Project measure / variable:   CSNA03   dist_l60_cocaine_in_d9

ID, description, units MPD:90415   dist_l60_cocaine_in_d9   distance traveled, last 60 min (post-injection), on successive days, cocaine sensitization, founders   [cm]  day 9  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, last 60 min (post-injection), on successive days, cocaine sensitization, founders day 9



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means21641.0   cm 23478.0   cm
Median of the strain means17468.0   cm 25472.0   cm
SD of the strain means± 15080.0 ± 15721.0
Coefficient of variation (CV)0.6968 0.6696
Min–max range of strain means2879.0   –   44938.0   cm 3123.0   –   43852.0   cm
Mean sample size per strain6.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 20162732.577 20162732.577 0.2321 0.631
strain 8 28873717435.6306 3609214679.4538 41.5474 < 0.0001
sex:strain 8 1455309890.6261 181913736.3283 2.0941 0.0427
Residuals 105 9121319519.9929 86869709.7142


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6622.0 15811.0   6 6455.0 2.3877 -1.0
129S1/SvImJ m 3123.0 3367.0   6 1374.0 1.078 293.6, 7786.0 -1.29
A/J f 2879.0 2439.0   12 704.1 0.8473 97.92, 7455.0 -1.24
A/J m 3782.0 3786.0   12 1093.0 1.0011 524.1, 14192.0 -1.25
C57BL/6J f 15991.0 2164.0   5 967.9 0.1353 13893.0, 19068.0 -0.37
C57BL/6J m 19959.0 5649.0   7 2135.0 0.283 12170.0, 26861.0 -0.22
C57BL/6NJ f 11240.0 0.0   1   0.0 0.0 11240.0, 11240.0 -0.69
C57BL/6NJ m 10109.0 0.0   1   0.0 0.0 10109.0, 10109.0 -0.85
CAST/EiJ f 40778.0 10385.0   6 4240.0 0.2547 32728.0, 60688.0 1.27
CAST/EiJ m 36974.0 12716.0   5 5687.0 0.3439 22205.0, 53369.0 0.86
DBA/2J f 18945.0 5862.0   3 3385.0 0.3094 13119.0, 24843.0 -0.18
DBA/2J m 40421.0 12639.0   4 6319.0 0.3127 23499.0, 53987.0 1.08
NOD/ShiLtJ f 27576.0 8821.0   6 3601.0 0.3199 13802.0, 38757.0 0.39
NOD/ShiLtJ m 30986.0 13043.0   6 5325.0 0.4209 13505.0, 51637.0 0.48
NZO/HlLtJ f 10140.0 4763.0   6 1945.0 0.4697 3520.0, 15857.0 -0.76
NZO/HlLtJ m 10757.0 5090.0   7 1924.0 0.4731 3431.0, 16852.0 -0.81
PWK/PhJ f 37303.0 6382.0   9 2127.0 0.1711 28621.0, 47584.0 1.04
PWK/PhJ m 43852.0 11394.0   9 3798.0 0.2598 30832.0, 68521.0 1.3
WSB/EiJ f 44938.0 17120.0   7 6471.0 0.381 30088.0, 81312.0 1.54
WSB/EiJ m 34814.0 13012.0   7 4918.0 0.3738 14617.0, 46305.0 0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6621.8833333334 3805.0341591594 14166.5631814265 -922.7965147597
129S1/SvImJ m 3123.2666666667 3805.0341591594 10667.9465147598 -4421.4131814264
A/J f 2878.7433333333 2690.5654565881 8213.6376158015 -2456.1509491348
A/J m 3781.8 2690.5654565881 9116.6942824682 -1553.0942824681
C57BL/6J f 15991.2 4168.2060820986 24255.9826839105 7726.4173160895
C57BL/6J m 19959.4285714286 3522.7771048709 26944.4448211421 12974.4123217151
CAST/EiJ f 40778.1666666666 3805.0341591594 48322.8465147597 33233.4868185735
CAST/EiJ m 36974.3999999999 4168.2060820986 45239.1826839104 28709.6173160894
DBA/2J f 18944.6666666667 5381.1309131761 29614.455231603 8274.8781017304
DBA/2J m 40420.75 4660.1960719003 49661.0579502435 31180.4420497565
NOD/ShiLtJ f 27575.6666666667 3805.0341591594 35120.3465147598 20030.9868185736
NOD/ShiLtJ m 30986.0000000001 3805.0341591594 38530.6798480932 23441.3201519069
NZO/HlLtJ f 10140.3333333334 3805.0341591594 17685.0131814265 2595.6534852403
NZO/HlLtJ m 10757.4285714285 3522.7771048709 17742.444821142 3772.412321715
PWK/PhJ f 37303.2222222222 3106.7973812668 43463.4275223846 31143.0169220599
PWK/PhJ m 43851.8888888889 3106.7973812668 50012.0941890512 37691.6835887265
WSB/EiJ f 44938.2857142857 3522.7771048709 51923.3019639992 37953.2694645722
WSB/EiJ m 34813.8571428571 3522.7771048709 41798.8733925707 27828.8408931436


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4872.575 2690.5654565881 10207.4692824682 -462.3192824681
A/J both 3330.2716666667 1902.5170795797 7102.6115907132 -442.0682573799
C57BL/6J both 17975.3142857143 2728.7314119132 23385.88460734 12564.7439640886
CAST/EiJ both 38876.2833333333 2821.8888574505 44471.5676608382 33280.9990058284
DBA/2J both 29682.7083333334 3559.2835421365 36740.1101044489 22625.3065622178
NOD/ShiLtJ both 29280.8333333334 2690.5654565881 34615.7276158015 23945.9390508653
NZO/HlLtJ both 10448.880952381 2592.6937479662 15589.7137161213 5308.0481886406
PWK/PhJ both 40577.5555555556 2196.8374960664 44933.4784968017 36221.6326143095
WSB/EiJ both 39876.0714285714 2490.9795794629 44815.2237854421 34936.9190717008




  GWAS USING LINEAR MIXED MODELS