Project measure / variable:   CSNA03   dist_l60_cocaine_in_d7

ID, description, units MPD:90409   dist_l60_cocaine_in_d7   distance traveled, last 60 min (post-injection), on successive days, cocaine sensitization, founders   [cm]  day 7  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, last 60 min (post-injection), on successive days, cocaine sensitization, founders day 7



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means21531.0   cm 19099.0   cm
Median of the strain means15195.0   cm 23221.0   cm
SD of the strain means± 17149.0 ± 13790.0
Coefficient of variation (CV)0.7965 0.722
Min–max range of strain means2323.0   –   50408.0   cm 2555.0   –   34919.0   cm
Mean sample size per strain6.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 364566570.7711 364566570.7711 2.6949 0.1037
strain 8 26483015139.8468 3310376892.4808 24.4701 < 0.0001
sex:strain 8 2067575751.4423 258446968.9303 1.9104 0.0659
Residuals 105 14204679115.5784 135282658.2436


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5819.0 13862.0   6 5659.0 2.3822 -0.92
129S1/SvImJ m 2698.0 2849.0   6 1163.0 1.0559 144.0, 6811.0 -1.19
A/J f 2323.0 1840.0   12 531.2 0.7923 63.5, 6647.0 -1.12
A/J m 2555.0 2373.0   12 685.0 0.9288 75.91, 8682.0 -1.2
C57BL/6J f 15826.0 2297.0   5 1027.0 0.1452 12234.0, 17999.0 -0.33
C57BL/6J m 20403.0 7071.0   7 2673.0 0.3466 10566.0, 31417.0 0.09
C57BL/6NJ f 7390.0 0.0   1   0.0 0.0 7390.0, 7390.0 -0.82
C57BL/6NJ m 3059.0 0.0   1   0.0 0.0 3059.0, 3059.0 -1.16
CAST/EiJ f 50408.0 29338.0   6 11977.0 0.582 31351.0, 106488.0 1.68
CAST/EiJ m 32483.0 13394.0   5 5990.0 0.4123 22787.0, 54993.0 0.97
DBA/2J f 14564.0 3317.0   3 1915.0 0.2278 10736.0, 16601.0 -0.41
DBA/2J m 32018.0 11940.0   4 5970.0 0.3729 14273.0, 39794.0 0.94
NOD/ShiLtJ f 32673.0 14135.0   6 5771.0 0.4326 20368.0, 57343.0 0.65
NOD/ShiLtJ m 29906.0 15228.0   6 6217.0 0.5092 14235.0, 49890.0 0.78
NZO/HlLtJ f 8328.0 5175.0   6 2113.0 0.6214 3451.0, 16818.0 -0.77
NZO/HlLtJ m 6914.0 3490.0   7 1319.0 0.5047 2577.0, 11538.0 -0.88
PWK/PhJ f 36974.0 10605.0   9 3535.0 0.2868 19688.0, 47582.0 0.9
PWK/PhJ m 34919.0 12453.0   9 4151.0 0.3566 11030.0, 52698.0 1.15
WSB/EiJ f 41001.0 18833.0   7 7118.0 0.4593 14644.0, 71432.0 1.14
WSB/EiJ m 26039.0 10632.0   7 4018.0 0.4083 10793.0, 40517.0 0.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5818.9 4748.3796928286 15234.0597807188 -3596.2597807189
129S1/SvImJ m 2697.9333333334 4748.3796928286 12113.0931140522 -6717.2264473855
A/J f 2322.625 3357.6114804476 8980.1483269011 -4334.8983269012
A/J m 2554.6908333334 3357.6114804476 9212.2141602345 -4102.8324935678
C57BL/6J f 15826.4 5201.5893387234 26140.1907888302 5512.6092111698
C57BL/6J m 20403.1428571429 4396.1453609726 29119.8870247025 11686.3986895832
CAST/EiJ f 50407.5 4748.3796928286 59822.6597807188 40992.3402192811
CAST/EiJ m 32483.1999999999 5201.5893387234 42796.9907888301 22169.4092111697
DBA/2J f 14563.6666666667 6715.2229608952 27878.713320469 1248.6200128644
DBA/2J m 32018.5 5815.5536762118 43549.6686547678 20487.3313452323
NOD/ShiLtJ f 32673.1666666667 4748.3796928286 42088.3264473856 23258.0068859479
NOD/ShiLtJ m 29906.3333333334 4748.3796928286 39321.4931140523 20491.1735526146
NZO/HlLtJ f 8328.1666666667 4748.3796928286 17743.3264473856 -1086.9931140521
NZO/HlLtJ m 6914.4285714285 4396.1453609726 15631.1727389881 -1802.3155961311
PWK/PhJ f 36974.2222222222 3877.0357841412 44661.6679920674 29286.776452377
PWK/PhJ m 34919.3333333333 3877.0357841412 42606.7791031785 27231.8875634881
WSB/EiJ f 41001.4285714286 4396.1453609726 49718.1727389882 32284.6844038689
WSB/EiJ m 26039.1428571429 4396.1453609726 34755.8870247025 17322.3986895832


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4258.4166666667 3357.6114804476 10915.9399935678 -2399.1066602345
A/J both 2438.6579166667 2374.1898464143 7146.2378070261 -2268.9219736928
C57BL/6J both 18114.7714285714 3405.2395541107 24866.7324273933 11362.8104297496
CAST/EiJ both 41445.3499999999 3521.4926294111 48427.819372153 34462.8806278469
DBA/2J both 23291.0833333333 4441.7024882199 32098.1588686292 14484.0077980374
NOD/ShiLtJ both 31289.7500000001 3357.6114804476 37947.2733269012 24632.2266730989
NZO/HlLtJ both 7621.2976190476 3235.4753801438 14036.6476207847 1205.9476173106
PWK/PhJ both 35946.7777777778 2741.4782938692 41382.6228116391 30510.9327439164
WSB/EiJ both 33520.2857142857 3108.5441958255 39683.9546250354 27356.616803536




  GWAS USING LINEAR MIXED MODELS