Project measure / variable:   CSNA03   dist_f30_cocaine_in_d19

ID, description, units MPD:90379   dist_f30_cocaine_in_d19   distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders   [cm]  day 19  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders day 19



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means7432.0   cm 6888.0   cm
Median of the strain means7827.0   cm 7667.0   cm
SD of the strain means± 4927.0 ± 3794.0
Coefficient of variation (CV)0.663 0.5508
Min–max range of strain means1009.0   –   14636.0   cm 1361.0   –   11746.0   cm
Mean sample size per strain6.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 26801179.3191 26801179.3191 5.0683 0.0264
strain 8 2155781655.8596 269472706.9825 50.9595 < 0.0001
sex:strain 8 104566454.1439 13070806.768 2.4718 0.017
Residuals 105 555237144.8588 5287972.8082


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1009.0 1561.0   6 637.2 1.5462 -1.3
129S1/SvImJ m 1606.0 1252.0   6 511.3 0.7797 -1.39
A/J f 2676.0 836.0   12 241.3 0.3124 1665.0, 3953.0 -0.97
A/J m 2800.0 1256.0   12 362.6 0.4486 1076.0, 5184.0 -1.08
C57BL/6J f 9895.0 1405.0   5 628.2 0.142 8363.0, 11883.0 0.5
C57BL/6J m 7056.0 1182.0   7 446.8 0.1675 5873.0, 9347.0 0.04
C57BL/6NJ f 3967.0 0.0   1   0.0 0.0 3967.0, 3967.0 -0.7
C57BL/6NJ m 6218.0 0.0   1   0.0 0.0 6218.0, 6218.0 -0.18
CAST/EiJ f 14636.0 3646.0   6 1489.0 0.2491 11424.0, 20088.0 1.46
CAST/EiJ m 9938.0 1762.0   5 788.2 0.1773 8260.0, 12908.0 0.8
DBA/2J f 7646.0 1025.0   3 592.0 0.1341 6851.0, 8803.0 0.04
DBA/2J m 10430.0 2109.0   4 1054.0 0.2022 8729.0, 13391.0 0.93
NOD/ShiLtJ f 12796.0 2381.0   6 971.9 0.1861 10500.0, 17147.0 1.09
NOD/ShiLtJ m 11746.0 2833.0   6 1157.0 0.2412 8862.0, 16852.0 1.28
NZO/HlLtJ f 1608.0 980.8   6 400.4 0.6099 714.5, 3386.0 -1.18
NZO/HlLtJ m 1361.0 710.9   7 268.7 0.5222 720.7, 2793.0 -1.46
PWK/PhJ f 8008.0 2452.0   9 817.2 0.3061 2741.0, 11366.0 0.12
PWK/PhJ m 8278.0 2700.0   9 900.1 0.3262 4475.0, 13079.0 0.37
WSB/EiJ f 12076.0 5366.0   7 2028.0 0.4443 5851.0, 19470.0 0.94
WSB/EiJ m 9445.0 2710.0   7 1024.0 0.2869 6390.0, 13222.0 0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1009.445 938.7911383067 2870.8944079379 -852.0044079379
129S1/SvImJ m 1606.2333333333 938.7911383067 3467.6827412712 -255.2160746046
A/J f 2675.8333333333 663.8255800145 3992.0768325219 1359.5898341448
A/J m 2800.0833333333 663.8255800145 4116.3268325219 1483.8398341448
C57BL/6J f 9895.0 1028.394166473 11934.1156607644 7855.8843392356
C57BL/6J m 7056.1428571429 869.1517053327 8779.5101337215 5332.7755805643
CAST/EiJ f 14636.5 938.7911383067 16497.9494079379 12775.0505920621
CAST/EiJ m 9938.2 1028.394166473 11977.3156607644 7899.0843392355
DBA/2J f 7645.6666666667 1327.651160029 10278.1536650438 5013.1796682895
DBA/2J m 10430.0 1149.779631949 12709.8006157268 8150.1993842731
NOD/ShiLtJ f 12795.5 938.7911383067 14656.9494079379 10934.0505920621
NOD/ShiLtJ m 11746.1666666667 938.7911383067 13607.6160746046 9884.7172587288
NZO/HlLtJ f 1608.0833333333 938.7911383067 3469.5327412712 -253.3660746046
NZO/HlLtJ m 1361.2285714286 869.1517053327 3084.5958480072 -362.1387051501
PWK/PhJ f 8008.4444444444 766.5197546326 9528.3115215957 6488.5773672932
PWK/PhJ m 8277.5555555556 766.5197546326 9797.4226327068 6757.6884784043
WSB/EiJ f 12075.7142857143 869.1517053327 13799.0815622929 10352.3470091357
WSB/EiJ m 9445.2857142857 869.1517053327 11168.6529908643 7721.9184377071


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1307.8391666667 663.8255800145 2624.0826658552 -8.4043325219
A/J both 2737.9583333333 469.3955691533 3668.6830373023 1807.2336293644
C57BL/6J both 8475.5714285714 673.2420160162 9810.485980889 7140.6568762539
CAST/EiJ both 12287.35 696.2261419609 13667.8378282954 10906.8621717046
DBA/2J both 9037.8333333333 878.1586993208 10779.0598151625 7296.6068515041
NOD/ShiLtJ both 12270.8333333334 663.8255800145 13587.0768325219 10954.5898341448
NZO/HlLtJ both 1484.6559523809 639.6783348383 2753.019925014 216.2919797479
PWK/PhJ both 8143.0 542.0113164142 9217.7083167558 7068.2916832442
WSB/EiJ both 10760.5 614.5830647206 11979.1046877437 9541.8953122563




  GWAS USING LINEAR MIXED MODELS