Project measure / variable:   CSNA03   amb_time_dark_LD_in

ID, description, units MPD:90148   amb_time_dark_LD_in   ambulatory time in dark, 20 min test (LD box), founders   [s]  
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 4-14wks
Procedure light-dark box
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  STRAIN COMPARISON PLOT
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CSNA03 - ambulatory time in dark, 20 min test (LD box), founders



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means56.86   s 51.02   s
Median of the strain means55.56   s 54.92   s
SD of the strain means± 25.24 ± 20.974
Coefficient of variation (CV)0.4439 0.4111
Min–max range of strain means14.76   –   90.25   s 17.784   –   77.12   s
Mean sample size per strain43.5   mice 42.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8075.5136 8075.5136 22.8272 < 0.0001
strain 9 458977.6763 50997.5196 144.1556 < 0.0001
sex:strain 9 8865.311 985.0346 2.7844 0.0032
Residuals 840 297164.4726 353.7672


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 14.76 20.874   49 2.982 1.4142 -1.67
129S1/SvImJ m 17.784 17.161   49 2.4515 0.965 -1.58
A/J f 23.058 22.233   60 2.8703 0.9642 -1.34
A/J m 22.395 16.945   61 2.1696 0.7567 -1.36
C57BL/6J f 51.96 15.867   60 2.0484 0.3054 -0.19
C57BL/6J m 54.46 14.809   59 1.9279 0.2719 27.24, 110.0 0.16
C57BL/6NJ f 41.945 13.122   13 3.6393 0.3128 12.84, 61.88 -0.59
C57BL/6NJ m 35.095 14.609   13 4.0517 0.4163 6.04, 58.88 -0.76
CAST/EiJ f 80.51 16.33   33 2.8426 0.2028 52.92, 112.4 0.94
CAST/EiJ m 69.2 18.322   30 3.3451 0.2648 6.04, 110.3 0.87
DBA/2J f 55.92 11.612   24 2.3703 0.2077 36.48, 76.16 -0.04
DBA/2J m 55.39 10.948   24 2.2347 0.1977 33.68, 74.24 0.21
NOD/ShiLtJ f 82.07 34.303   47 5.0037 0.418 35.12, 285.8 1.0
NOD/ShiLtJ m 74.6 17.33   44 2.6127 0.2323 25.32, 112.9 1.12
NZO/HlLtJ f 55.21 18.838   47 2.7479 0.3412 26.04, 104.1 -0.07
NZO/HlLtJ m 42.569 10.532   46 1.5528 0.2474 24.08, 66.8 -0.4
PWK/PhJ f 72.95 20.169   47 2.942 0.2765 46.16, 153.9 0.64
PWK/PhJ m 61.58 17.467   48 2.5211 0.2836 0.6, 121.9 0.5
WSB/EiJ f 90.25 18.475   55 2.4912 0.2047 47.12, 130.9 1.32
WSB/EiJ m 77.12 19.775   51 2.769 0.2564 43.16, 120.8 1.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 14.7602040816 2.6869572706 20.0341426429 9.4862655204
129S1/SvImJ m 17.783877551 2.6869572706 23.0578161123 12.5099389898
A/J f 23.0576666667 2.4281928442 27.8237044505 18.2916288828
A/J m 22.3947540984 2.4082073781 27.1215645667 17.66794363
C57BL/6J f 51.9586666667 2.4281928442 56.7247044505 47.1926288828
C57BL/6J m 54.4647457627 2.4486842863 59.2710039878 49.6584875376
C57BL/6NJ f 41.9446153846 5.2165950383 52.1837070264 31.7055237428
C57BL/6NJ m 35.0953846154 5.2165950383 45.3344762572 24.8562929736
CAST/EiJ f 80.5127272727 3.2741745632 86.9392513095 74.086203236
CAST/EiJ m 69.202 3.4339832523 75.9421952727 62.4618047273
DBA/2J f 55.915 3.8393099929 63.4507674057 48.3792325943
DBA/2J m 55.3883333333 3.8393099929 62.9241007391 47.8525659276
NOD/ShiLtJ f 82.0680851064 2.743530996 87.4530661302 76.6831040826
NOD/ShiLtJ m 74.6 2.8355183482 80.1655330739 69.0344669261
NZO/HlLtJ f 55.2117021277 2.743530996 60.5966831514 49.8267211039
NZO/HlLtJ m 42.5691304348 2.7731916525 48.0123291616 37.125931708
PWK/PhJ f 72.9514893617 2.743530996 78.3364703855 67.5665083379
PWK/PhJ m 61.58375 2.7148021311 66.912342234 56.255157766
WSB/EiJ f 90.2461818182 2.5361647112 95.2241459319 85.2682177045
WSB/EiJ m 77.1176470588 2.6337449268 82.287140851 71.9481532666


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 16.2720408163 1.8999657068 20.0012785365 12.5428030961
A/J both 22.7262103825 1.7099402961 26.0824677237 19.3699530413
C57BL/6J both 53.2117062147 1.7242516654 56.5960537989 49.8273586305
C57BL/6NJ both 38.52 3.6886897263 45.7601311331 31.2798688669
CAST/EiJ both 74.8573636364 2.3723648564 79.5138226856 70.2009045871
DBA/2J both 55.6516666667 2.7148021311 60.9802589007 50.3230744326
NOD/ShiLtJ both 78.3340425532 1.9727599086 82.2061601593 74.4619249471
NZO/HlLtJ both 48.8904162812 1.9504841878 52.718811278 45.0620212844
PWK/PhJ both 67.2676196809 1.9298389141 71.0554922969 63.4797470648
WSB/EiJ both 83.6819144385 1.8281646385 87.2702215876 80.0936072894




  GWAS USING LINEAR MIXED MODELS