Phenotype measure:   Neuner1   Ymaze_dist_10mo


  STRAIN COMPARISON PLOT
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Neuner1 - distance traveled in Y-maze 10 mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains8 strains
Mean of the strain means11.979   m 10.441   m
Median of the strain means11.057   m 9.862   m
SD of the strain means± 3.8716 ± 3.1989
Coefficient of variation (CV)0.3232 0.3064
Min–max range of strain means6.741   –   21.79   m 5.296   –   16.708   m
Mean sample size per strain3.5   mice 2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1514 0.1514 0.0169 0.8978
strain 2 155.9681 77.9841 8.7259 0.0019
sex:strain 2 60.8477 30.4239 3.4042 0.0534
Residuals 20 178.7424 8.9371


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 12.34 2.7231   3 1.5722 0.2207 10.23, 15.414 0.59
(B6.5XFAD x B6)F1-Ntg f 16.907 0.0   1   0.0 0.0 16.907, 16.907 1.27
(B6.5XFAD x B6)F1-Ntg m 9.5395 0.39386   2   0.2785 0.0413 9.261, 9.818 -0.28
(B6.5XFAD x BXD100)F1-ADtg m 5.296 2.3589   2   1.668 0.4454 3.628, 6.964 -1.61
(B6.5XFAD x BXD14)F1-ADtg f 10.12 0.0   1   0.0 0.0 10.12, 10.12 -0.48
(B6.5XFAD x BXD14)F1-Ntg f 10.617 5.6717   2   4.0105 0.5342 6.606, 14.627 -0.35
(B6.5XFAD x BXD16)F1-ADtg f 6.741 2.3048   4 1.1524 0.3419 4.25, 9.103 -1.35
(B6.5XFAD x BXD22)F1-ADtg f 18.834 17.33   2   12.254 0.9202 6.579, 31.088 1.77
(B6.5XFAD x BXD22)F1-Ntg f 7.98 3.0999   3 1.7897 0.3885 4.708, 10.873 -1.03
(B6.5XFAD x BXD2)F1-ADtg f 9.4955 2.4476   4 1.2238 0.2578 7.408, 12.836 -0.64
(B6.5XFAD x BXD2)F1-Ntg f 11.77 0.0   1   0.0 0.0 11.77, 11.77 -0.05
(B6.5XFAD x BXD34)F1-ADtg f 13.883 2.7747   2   1.962 0.1999 11.921, 15.845 0.49
(B6.5XFAD x BXD34)F1-Ntg f 13.942 0.0   1   0.0 0.0 13.942, 13.942 0.51
(B6.5XFAD x BXD42)F1-ADtg f 9.3013 3.076   3 1.7759 0.3307 6.795, 12.734 -0.69
(B6.5XFAD x BXD42)F1-Ntg f 19.812 0.0   1   0.0 0.0 19.812, 19.812 2.02
(B6.5XFAD x BXD44)F1-ADtg f 7.4806 2.5895   5 1.1581 0.3462 4.968, 10.983 -1.16
(B6.5XFAD x BXD44)F1-ADtg m 9.9985 0.48578   2   0.3435 0.0486 9.655, 10.342 -0.14
(B6.5XFAD x BXD51)F1-ADtg f 9.8878 2.4303   4 1.2151 0.2458 7.963, 13.447 -0.54
(B6.5XFAD x BXD51)F1-Ntg f 14.616 3.0811   4 1.5406 0.2108 10.513, 17.801 0.68
(B6.5XFAD x BXD55)F1-ADtg f 13.685 2.3309   4 1.1654 0.1703 11.319, 15.932 0.44
(B6.5XFAD x BXD55)F1-Ntg f 9.545 1.9474   2   1.377 0.204 8.168, 10.922 -0.63
(B6.5XFAD x BXD65)F1-ADtg f 14.734 2.6226   7 0.99124 0.178 12.672, 20.237 0.71
(B6.5XFAD x BXD65)F1-ADtg m 10.346 0.95672   2   0.6765 0.0925 9.67, 11.023 -0.03
(B6.5XFAD x BXD65)F1-Ntg f 12.857 3.3895   8 1.1984 0.2636 8.071, 18.333 0.23
(B6.5XFAD x BXD65)F1-Ntg m 16.708 5.3924   2   3.813 0.3227 12.895, 20.521 1.96
(B6.5XFAD x BXD68)F1-ADtg m 9.7255 2.0552   4 1.0276 0.2113 7.539, 12.5 -0.22
(B6.5XFAD x BXD68)F1-Ntg f 7.0828 1.8292   6 0.74675 0.2583 4.55, 9.981 -1.26
(B6.5XFAD x BXD68)F1-Ntg m 9.575 0.0   1   0.0 0.0 9.575, 9.575 -0.27
(B6.5XFAD x BXD75)F1-ADtg f 7.1755 3.1181   4 1.5591 0.4345 3.171, 9.657 -1.24
(B6.5XFAD x BXD75)F1-Ntg f 9.9397 2.0668   6 0.84378 0.2079 6.492, 11.698 -0.53
(B6.5XFAD x BXD81)F1-ADtg f 11.522 2.1725   6 0.88692 0.1886 8.672, 14.283 -0.12
(B6.5XFAD x BXD81)F1-Ntg f 14.64 3.2401   5 1.449 0.2213 10.361, 18.279 0.69
(B6.5XFAD x BXD87)F1-ADtg f 9.1824 2.0844   5 0.93216 0.227 6.325, 11.891 -0.72
(B6.5XFAD x BXD99)F1-ADtg f 12.912 0.0   1   0.0 0.0 12.912, 12.912 0.24
(B6.5XFAD x BXD99)F1-Ntg f 21.79 0.0   1   0.0 0.0 21.79, 21.79 2.53
(B6.5XFAD x D2)F1-ADtg f 11.057 1.7143   3 0.98974 0.155 9.83, 13.016 -0.24
(B6.5XFAD x D2)F1-Ntg f 9.8755 3.7234   6 1.5201 0.377 6.486, 16.024 -0.54


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x BXD44)F1-ADtg f 7.4806 1.3369 10.2694 4.6918
(B6.5XFAD x BXD44)F1-ADtg m 9.9985 2.1139 14.408 5.589
(B6.5XFAD x BXD65)F1-ADtg f 14.7339 1.1299 17.0908 12.3769
(B6.5XFAD x BXD65)F1-ADtg m 10.3465 2.1139 14.756 5.937
(B6.5XFAD x BXD65)F1-Ntg f 12.8572 1.0569 15.062 10.6525
(B6.5XFAD x BXD65)F1-Ntg m 16.708 2.1139 21.1175 12.2985


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x BXD44)F1-ADtg both 8.7395 1.2506 11.3483 6.1308
(B6.5XFAD x BXD65)F1-ADtg both 12.5402 1.1985 15.0401 10.0402
(B6.5XFAD x BXD65)F1-Ntg both 14.7826 1.1817 17.2476 12.3176




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA