Phenotype measure:   Neuner1   Ymaze_age_onset

ID, description, units MPD:65921   Ymaze_age_onset   age at onset of working memory deficits (age at which spontaneous alternation percentage dropped below 50%, past 6 mo)   [n]
Data set, strains Neuner1   F1 AD-BXD   53 strains     sex: both     age: 23-65wks
Procedure Y-maze
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - age at onset of working memory deficits (age at which spontaneous alternation percentage dropped below 50%, past 6 mo)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested51 strains35 strains
Mean of the strain means10.296   n 10.974   n
Median of the strain means10.6   n 10.5   n
SD of the strain means± 3.2132 ± 3.2726
Coefficient of variation (CV)0.3121 0.2982
Min–max range of strain means4.0   –   16.0   n 6.0   –   16.0   n
Mean sample size per strain4.5   mice 4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 44.0938 44.0938 2.5568 0.1111
strain 24 883.7604 36.8233 2.1352 0.0021
sex:strain 24 617.0309 25.7096 1.4908 0.07
Residuals 253 4363.1809 17.2458


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 8.5 5.2599   4 2.63 0.6188 4.0, 16.0 -0.56
(B6.5XFAD x B6)F1-ADtg m 14.552 2.4434   29 0.45374 0.1679 6.0, 16.0 1.09
(B6.5XFAD x B6)F1-Ntg f 13.818 4.8542   11 1.4636 0.3513 4.0, 16.0 1.1
(B6.5XFAD x B6)F1-Ntg m 12.5 4.7578   12 1.3734 0.3806 4.0, 16.0 0.47
(B6.5XFAD x BXD100)F1-ADtg f 11.0 7.0711   2   5.0 0.6428 6.0, 16.0 0.22
(B6.5XFAD x BXD100)F1-ADtg m 12.571 4.1173   7 1.5562 0.3275 6.0, 16.0 0.49
(B6.5XFAD x BXD100)F1-Ntg f 11.0 5.7735   4 2.8868 0.5249 6.0, 16.0 0.22
(B6.5XFAD x BXD100)F1-Ntg m 14.333 4.0825   6 1.6667 0.2848 6.0, 16.0 1.03
(B6.5XFAD x BXD14)F1-ADtg f 4.0 0.0   3 0.0 0.0 4.0, 4.0 -1.96
(B6.5XFAD x BXD14)F1-Ntg f 12.0 2.8284   2   2.0 0.2357 10.0, 14.0 0.53
(B6.5XFAD x BXD16)F1-ADtg f 7.5 2.5166   4 1.2583 0.3355 4.0, 10.0 -0.87
(B6.5XFAD x BXD22)F1-ADtg f 7.0 1.4142   2   1.0 0.202 6.0, 8.0 -1.03
(B6.5XFAD x BXD22)F1-Ntg f 13.333 3.0551   3 1.7638 0.2291 10.0, 16.0 0.95
(B6.5XFAD x BXD2)F1-ADtg f 10.0 0.0   3 0.0 0.0 10.0, 10.0 -0.09
(B6.5XFAD x BXD32)F1-ADtg f 8.0 4.0   3 2.3094 0.5 4.0, 12.0 -0.71
(B6.5XFAD x BXD32)F1-ADtg m 15.333 1.1547   3 0.66667 0.0753 14.0, 16.0 1.33
(B6.5XFAD x BXD32)F1-Ntg f 12.0 4.0   3 2.3094 0.3333 8.0, 16.0 0.53
(B6.5XFAD x BXD32)F1-Ntg m 9.0 7.0711   2   5.0 0.7857 4.0, 14.0 -0.6
(B6.5XFAD x BXD34)F1-ADtg f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.96
(B6.5XFAD x BXD42)F1-ADtg f 6.6667 2.3094   3 1.3333 0.3464 4.0, 8.0 -1.13
(B6.5XFAD x BXD42)F1-Ntg f 14.0 0.0   1   0.0 0.0 14.0, 14.0 1.15
(B6.5XFAD x BXD44)F1-ADtg f 10.615 4.5007   13 1.2483 0.424 4.0, 16.0 0.1
(B6.5XFAD x BXD44)F1-ADtg m 11.75 4.4641   8 1.5783 0.3799 6.0, 16.0 0.24
(B6.5XFAD x BXD44)F1-Ntg f 16.0 0.0   1   0.0 0.0 16.0, 16.0 1.78
(B6.5XFAD x BXD44)F1-Ntg m 6.6667 1.1547   3 0.66667 0.1732 6.0, 8.0 -1.32
(B6.5XFAD x BXD51)F1-ADtg f 11.333 3.9328   6 1.6055 0.347 6.0, 16.0 0.32
(B6.5XFAD x BXD51)F1-Ntg f 11.5 4.4347   4 2.2174 0.3856 6.0, 16.0 0.37
(B6.5XFAD x BXD55)F1-ADtg f 7.6667 3.4448   6 1.4063 0.4493 4.0, 12.0 -0.82
(B6.5XFAD x BXD55)F1-Ntg f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.09
(B6.5XFAD x BXD56)F1-ADtg m 13.333 4.6188   3 2.6667 0.3464 8.0, 16.0 0.72
(B6.5XFAD x BXD56)F1-Ntg f 16.0 0.0   2   0.0 0.0 16.0, 16.0 1.78
(B6.5XFAD x BXD56)F1-Ntg m 16.0 0.0   1   0.0 0.0 16.0, 16.0 1.54
(B6.5XFAD x BXD60)F1-ADtg f 7.5 3.4157   4 1.7078 0.4554 4.0, 12.0 -0.87
(B6.5XFAD x BXD60)F1-ADtg m 8.8 4.1473   5 1.8547 0.4713 4.0, 14.0 -0.66
(B6.5XFAD x BXD60)F1-Ntg f 12.0 5.6569   2   4.0 0.4714 8.0, 16.0 0.53
(B6.5XFAD x BXD61)F1-ADtg f 9.1429 4.2984   7 1.6246 0.4701 4.0, 16.0 -0.36
(B6.5XFAD x BXD61)F1-ADtg m 10.0 3.4641   3 2.0 0.3464 6.0, 12.0 -0.3
(B6.5XFAD x BXD61)F1-Ntg f 11.2 5.2154   5 2.3324 0.4657 4.0, 16.0 0.28
(B6.5XFAD x BXD61)F1-Ntg m 11.0 4.858   6 1.9833 0.4416 6.0, 16.0 0.01
(B6.5XFAD x BXD62)F1-ADtg f 12.0 0.0   1   0.0 0.0 12.0, 12.0 0.53
(B6.5XFAD x BXD62)F1-ADtg m 10.0 2.8284   2   2.0 0.2828 8.0, 12.0 -0.3
(B6.5XFAD x BXD62)F1-Ntg f 15.0 1.4142   2   1.0 0.0943 14.0, 16.0 1.46
(B6.5XFAD x BXD62)F1-Ntg m 7.3333 5.7735   3 3.3333 0.7873 4.0, 14.0 -1.11
(B6.5XFAD x BXD65)F1-ADtg f 10.0 5.2915   7 2.0 0.5292 4.0, 16.0 -0.09
(B6.5XFAD x BXD65)F1-ADtg m 10.0 8.4853   2   6.0 0.8485 4.0, 16.0 -0.3
(B6.5XFAD x BXD65)F1-Ntg f 9.25 4.3997   8 1.5555 0.4756 4.0, 16.0 -0.33
(B6.5XFAD x BXD65)F1-Ntg m 7.0 1.4142   2   1.0 0.202 6.0, 8.0 -1.21
(B6.5XFAD x BXD66)F1-ADtg f 12.0 6.9282   3 4.0 0.5774 4.0, 16.0 0.53
(B6.5XFAD x BXD66)F1-ADtg m 9.6 4.98   5 2.2271 0.5187 6.0, 16.0 -0.42
(B6.5XFAD x BXD66)F1-Ntg f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.96
(B6.5XFAD x BXD66)F1-Ntg m 6.0 0.0   2   0.0 0.0 6.0, 6.0 -1.52
(B6.5XFAD x BXD68)F1-ADtg f 12.0 4.0   3 2.3094 0.3333 8.0, 16.0 0.53
(B6.5XFAD x BXD68)F1-ADtg m 7.4286 6.0788   7 2.2976 0.8183 2.0, 16.0 -1.08
(B6.5XFAD x BXD68)F1-Ntg f 9.8 4.3665   10 1.3808 0.4456 4.0, 16.0 -0.15
(B6.5XFAD x BXD68)F1-Ntg m 14.0 2.8284   2   2.0 0.202 12.0, 16.0 0.92
(B6.5XFAD x BXD69)F1-ADtg f 9.3333 5.3166   6 2.1705 0.5696 4.0, 16.0 -0.3
(B6.5XFAD x BXD69)F1-ADtg m 10.0 4.899   5 2.1909 0.4899 4.0, 16.0 -0.3
(B6.5XFAD x BXD69)F1-Ntg f 12.0 3.266   4 1.633 0.2722 8.0, 16.0 0.53
(B6.5XFAD x BXD69)F1-Ntg m 14.333 3.2042   6 1.3081 0.2235 8.0, 16.0 1.03
(B6.5XFAD x BXD70)F1-ADtg f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.34
(B6.5XFAD x BXD70)F1-ADtg m 15.0 1.4142   2   1.0 0.0943 14.0, 16.0 1.23
(B6.5XFAD x BXD70)F1-Ntg f 16.0 0.0   2   0.0 0.0 16.0, 16.0 1.78
(B6.5XFAD x BXD70)F1-Ntg m 16.0 0.0   1   0.0 0.0 16.0, 16.0 1.54
(B6.5XFAD x BXD75)F1-ADtg f 10.0 4.6188   4 2.3094 0.4619 6.0, 14.0 -0.09
(B6.5XFAD x BXD75)F1-ADtg m 10.5 4.4347   4 2.2174 0.4224 6.0, 16.0 -0.14
(B6.5XFAD x BXD75)F1-Ntg f 12.333 3.4448   6 1.4063 0.2793 8.0, 16.0 0.63
(B6.5XFAD x BXD75)F1-Ntg m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.91
(B6.5XFAD x BXD77)F1-ADtg f 9.5 4.4347   4 2.2174 0.4668 6.0, 16.0 -0.25
(B6.5XFAD x BXD77)F1-ADtg m 16.0 0.0   3 0.0 0.0 16.0, 16.0 1.54
(B6.5XFAD x BXD77)F1-Ntg f 13.4 2.5033   10 0.79162 0.1868 8.0, 16.0 0.97
(B6.5XFAD x BXD77)F1-Ntg m 13.333 3.0111   6 1.2293 0.2258 8.0, 16.0 0.72
(B6.5XFAD x BXD81)F1-ADtg f 8.3333 3.4448   6 1.4063 0.4134 4.0, 14.0 -0.61
(B6.5XFAD x BXD81)F1-Ntg f 7.6 3.5777   5 1.6 0.4708 4.0, 12.0 -0.84
(B6.5XFAD x BXD87)F1-ADtg f 10.6 4.5265   10 1.4314 0.427 4.0, 16.0 0.09
(B6.5XFAD x BXD87)F1-ADtg m 10.0 3.6515   4 1.8257 0.3651 6.0, 14.0 -0.3
(B6.5XFAD x BXD87)F1-Ntg f 5.3333 1.1547   3 0.66667 0.2165 4.0, 6.0 -1.54
(B6.5XFAD x BXD87)F1-Ntg m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.52
(B6.5XFAD x BXD89)F1-ADtg m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.52
(B6.5XFAD x BXD89)F1-Ntg f 16.0 0.0   2   0.0 0.0 16.0, 16.0 1.78
(B6.5XFAD x BXD89)F1-Ntg m 6.0 0.0   2   0.0 0.0 6.0, 6.0 -1.52
(B6.5XFAD x BXD99)F1-ADtg f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.34
(B6.5XFAD x BXD99)F1-Ntg f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.34
(B6.5XFAD x D2)F1-ADtg f 14.0 2.8284   16 0.70711 0.202 6.0, 16.0 1.15
(B6.5XFAD x D2)F1-ADtg m 13.714 3.1472   7 1.1895 0.2295 8.0, 16.0 0.84
(B6.5XFAD x D2)F1-Ntg f 12.857 3.1097   14 0.83111 0.2419 8.0, 16.0 0.8
(B6.5XFAD x D2)F1-Ntg m 12.0 5.4772   5 2.4495 0.4564 6.0, 16.0 0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 8.5 2.0764 12.5892 4.4108
(B6.5XFAD x B6)F1-ADtg m 14.5517 0.7712 16.0704 13.033
(B6.5XFAD x B6)F1-Ntg f 13.8182 1.2521 16.2841 11.3523
(B6.5XFAD x B6)F1-Ntg m 12.5 1.1988 14.8609 10.1391
(B6.5XFAD x BXD100)F1-ADtg f 11.0 2.9365 16.783 5.217
(B6.5XFAD x BXD100)F1-ADtg m 12.5714 1.5696 15.6626 9.4803
(B6.5XFAD x BXD100)F1-Ntg f 11.0 2.0764 15.0892 6.9108
(B6.5XFAD x BXD100)F1-Ntg m 14.3333 1.6954 17.6722 10.9945
(B6.5XFAD x BXD32)F1-ADtg f 8.0 2.3976 12.7218 3.2782
(B6.5XFAD x BXD32)F1-ADtg m 15.3333 2.3976 20.0552 10.6115
(B6.5XFAD x BXD32)F1-Ntg f 12.0 2.3976 16.7218 7.2782
(B6.5XFAD x BXD32)F1-Ntg m 9.0 2.9365 14.783 3.217
(B6.5XFAD x BXD44)F1-ADtg f 10.6154 1.1518 12.8837 8.3471
(B6.5XFAD x BXD44)F1-ADtg m 11.75 1.4682 14.6415 8.8585
(B6.5XFAD x BXD60)F1-ADtg f 7.5 2.0764 11.5892 3.4108
(B6.5XFAD x BXD60)F1-ADtg m 8.8 1.8572 12.4575 5.1425
(B6.5XFAD x BXD61)F1-ADtg f 9.1429 1.5696 12.234 6.0517
(B6.5XFAD x BXD61)F1-ADtg m 10.0 2.3976 14.7218 5.2782
(B6.5XFAD x BXD61)F1-Ntg f 11.2 1.8572 14.8575 7.5425
(B6.5XFAD x BXD61)F1-Ntg m 11.0 1.6954 14.3388 7.6612
(B6.5XFAD x BXD62)F1-Ntg f 15.0 2.9365 20.783 9.217
(B6.5XFAD x BXD62)F1-Ntg m 7.3333 2.3976 12.0552 2.6115
(B6.5XFAD x BXD65)F1-ADtg f 10.0 1.5696 13.0912 6.9088
(B6.5XFAD x BXD65)F1-ADtg m 10.0 2.9365 15.783 4.217
(B6.5XFAD x BXD65)F1-Ntg f 9.25 1.4682 12.1415 6.3585
(B6.5XFAD x BXD65)F1-Ntg m 7.0 2.9365 12.783 1.217
(B6.5XFAD x BXD66)F1-ADtg f 12.0 2.3976 16.7218 7.2782
(B6.5XFAD x BXD66)F1-ADtg m 9.6 1.8572 13.2575 5.9425
(B6.5XFAD x BXD68)F1-ADtg f 12.0 2.3976 16.7218 7.2782
(B6.5XFAD x BXD68)F1-ADtg m 7.4286 1.5696 10.5197 4.3374
(B6.5XFAD x BXD68)F1-Ntg f 9.8 1.3132 12.3863 7.2137
(B6.5XFAD x BXD68)F1-Ntg m 14.0 2.9365 19.783 8.217
(B6.5XFAD x BXD69)F1-ADtg f 9.3333 1.6954 12.6722 5.9945
(B6.5XFAD x BXD69)F1-ADtg m 10.0 1.8572 13.6575 6.3425
(B6.5XFAD x BXD69)F1-Ntg f 12.0 2.0764 16.0892 7.9108
(B6.5XFAD x BXD69)F1-Ntg m 14.3333 1.6954 17.6722 10.9945
(B6.5XFAD x BXD75)F1-ADtg f 10.0 2.0764 14.0892 5.9108
(B6.5XFAD x BXD75)F1-ADtg m 10.5 2.0764 14.5892 6.4108
(B6.5XFAD x BXD77)F1-ADtg f 9.5 2.0764 13.5892 5.4108
(B6.5XFAD x BXD77)F1-ADtg m 16.0 2.3976 20.7218 11.2782
(B6.5XFAD x BXD77)F1-Ntg f 13.4 1.3132 15.9863 10.8137
(B6.5XFAD x BXD77)F1-Ntg m 13.3333 1.6954 16.6722 9.9945
(B6.5XFAD x BXD87)F1-ADtg f 10.6 1.3132 13.1863 8.0137
(B6.5XFAD x BXD87)F1-ADtg m 10.0 2.0764 14.0892 5.9108
(B6.5XFAD x BXD89)F1-Ntg f 16.0 2.9365 21.783 10.217
(B6.5XFAD x BXD89)F1-Ntg m 6.0 2.9365 11.783 0.217
(B6.5XFAD x D2)F1-ADtg f 14.0 1.0382 16.0446 11.9554
(B6.5XFAD x D2)F1-ADtg m 13.7143 1.5696 16.8055 10.6231
(B6.5XFAD x D2)F1-Ntg f 12.8571 1.1099 15.0429 10.6714
(B6.5XFAD x D2)F1-Ntg m 12.0 1.8572 15.6575 8.3425


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 11.5259 1.1075 13.7069 9.3448
(B6.5XFAD x B6)F1-Ntg both 13.1591 0.8667 14.866 11.4521
(B6.5XFAD x BXD100)F1-ADtg both 11.7857 1.6648 15.0644 8.507
(B6.5XFAD x BXD100)F1-Ntg both 12.6667 1.3403 15.3063 10.0271
(B6.5XFAD x BXD32)F1-ADtg both 11.6667 1.6954 15.0055 8.3278
(B6.5XFAD x BXD32)F1-Ntg both 10.5 1.8955 14.2329 6.7671
(B6.5XFAD x BXD44)F1-ADtg both 11.1827 0.933 13.0202 9.3452
(B6.5XFAD x BXD60)F1-ADtg both 8.15 1.3929 10.8931 5.4069
(B6.5XFAD x BXD61)F1-ADtg both 9.5714 1.4329 12.3933 6.7496
(B6.5XFAD x BXD61)F1-Ntg both 11.1 1.2573 13.5762 8.6238
(B6.5XFAD x BXD62)F1-Ntg both 11.1667 1.8955 14.8996 7.4337
(B6.5XFAD x BXD65)F1-ADtg both 10.0 1.6648 13.2787 6.7213
(B6.5XFAD x BXD65)F1-Ntg both 8.125 1.6415 11.3578 4.8922
(B6.5XFAD x BXD66)F1-ADtg both 10.8 1.5164 13.7864 7.8136
(B6.5XFAD x BXD68)F1-ADtg both 9.7143 1.4329 12.5361 6.8924
(B6.5XFAD x BXD68)F1-Ntg both 11.9 1.6084 15.0675 8.7325
(B6.5XFAD x BXD69)F1-ADtg both 9.6667 1.2573 12.1428 7.1905
(B6.5XFAD x BXD69)F1-Ntg both 13.1667 1.3403 15.8063 10.5271
(B6.5XFAD x BXD75)F1-ADtg both 10.25 1.4682 13.1415 7.3585
(B6.5XFAD x BXD77)F1-ADtg both 12.75 1.5859 15.8732 9.6268
(B6.5XFAD x BXD77)F1-Ntg both 13.3667 1.0722 15.4783 11.255
(B6.5XFAD x BXD87)F1-ADtg both 10.3 1.2284 12.7192 7.8808
(B6.5XFAD x BXD89)F1-Ntg both 11.0 2.0764 15.0892 6.9108
(B6.5XFAD x D2)F1-ADtg both 13.8571 0.9409 15.7102 12.0041
(B6.5XFAD x D2)F1-Ntg both 12.4286 1.0818 14.559 10.2981




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA