Project measure / variable:   CSNA02   EtOH_licks_d3

ID, description, units MPD:62228   EtOH_licks_d3   licks on ethanol bottle as a percentage of total licks 'drinking in the dark'   [%]  day 3  
ethanol study
Data set, strains CSNA02   inbred   18 strains     sex: both     age: 16-39wks
Procedure bottle choice test
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  STRAIN COMPARISON PLOT
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CSNA02 - licks on ethanol bottle as a percentage of total licks 'drinking in the dark' day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains18 strains
Mean of the strain means20.641   % 18.485   %
Median of the strain means20.462   % 13.808   %
SD of the strain means± 18.164 ± 16.699
Coefficient of variation (CV)0.88 0.9034
Min–max range of strain means2.62   –   72.82   % 0.52   –   55.84   %
Mean sample size per strain5.4   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 709.4878 709.4878 1.659 0.1996
strain 16 50552.5414 3159.5338 7.388 < 0.0001
sex:strain 16 9710.2827 606.8927 1.4191 0.1383
Residuals 163 69708.0069 427.6565


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 21.6 34.537   8 12.211 1.5989 0.03, 98.31 0.05
129S1/SvImJ m 17.57 22.434   6 9.1585 1.2768 1.45, 50.24 -0.05
A/J f 29.931 33.906   9 11.302 1.1328 2.18, 98.23 0.51
A/J m 19.931 27.644   9 9.2147 1.387 2.76, 83.33 0.09
C57BL/6J f 31.705 22.162   8 7.8353 0.699 4.67, 63.54 0.61
C57BL/6J m 55.84 23.116   7 8.7371 0.414 30.54, 87.72 2.24
CAST/EiJ f 19.376 24.036   8 8.4979 1.2405 4.82, 77.7 -0.07
CAST/EiJ m 13.09 4.6409   8 1.6408 0.3545 6.56, 19.43 -0.32
CC002/UncJ f 6.4767 5.2146   3 3.0107 0.8051 2.9, 12.46 -0.78
CC002/UncJ m 7.35 3.5043   3 2.0232 0.4768 3.95, 10.95 -0.67
CC004/TauUncJ f 22.226 29.693   5 13.279 1.336 7.43, 75.23 0.09
CC004/TauUncJ m 9.27 8.7917   9 2.9306 0.9484 2.45, 31.75 -0.55
CC006/TauUncJ f 31.29 22.005   3 12.705 0.7033 9.36, 53.37 0.59
CC006/TauUncJ m 19.99 25.747   3 14.865 1.288 5.0, 49.72 0.09
CC011/UncJ f 49.135 62.49   2   44.185 1.2717 4.95, 93.32 1.57
CC011/UncJ m 14.525 19.438   2   13.745 1.3383 0.78, 28.27 -0.24
CC012/GeniUncJ f 8.9633 4.7756   3 2.7572 0.5328 4.06, 13.6 -0.64
CC012/GeniUncJ m 28.27 23.712   3 13.69 0.8388 10.05, 55.08 0.59
CC025/GeniUncJ f 7.68 0.0   1   0.0 0.0 7.68, 7.68 -0.71
CC025/GeniUncJ m 0.52 0.0   1   0.0 0.0 0.52, 0.52 -1.08
CC028/GeniUncJ f 4.47 3.9514   3 2.2814 0.884 1.9, 9.02 -0.89
CC028/GeniUncJ m 3.74 1.2663   3 0.73112 0.3386 2.8, 5.18 -0.88
CC032/GeniUncJ f 4.0733 3.3189   3 1.9162 0.8148 1.98, 7.9 -0.91
CC032/GeniUncJ m 12.03 13.0   3 7.5053 1.0806 4.4, 27.04 -0.39
CC041/TauUncJ f 7.0544 4.0051   9 1.335 0.5677 2.01, 13.35 -0.75
CC041/TauUncJ m 3.4644 3.6944   9 1.2315 1.0664 0.63, 12.26 -0.9
CC061/GeniUncJ f 2.62 1.0041   2   0.71 0.3832 1.91, 3.33 -0.99
CC061/GeniUncJ m 43.327 43.342   3 25.023 1.0004 0.7, 87.35 1.49
NOD/ShiLtJ f 6.96 8.5853   6 3.5049 1.2335 0.1, 22.14 -0.75
NOD/ShiLtJ m 7.935 11.992   6 4.8956 1.5112 0.02, 26.0 -0.63
NZO/HlLtJ f 21.549 12.863   9 4.2877 0.5969 3.98, 39.37 0.05
NZO/HlLtJ m 16.511 16.014   9 5.3382 0.9699 3.49, 56.06 -0.12
PWK/PhJ f 72.82 14.227   8 5.0301 0.1954 48.05, 91.58 2.87
PWK/PhJ m 54.18 22.245   9 7.4151 0.4106 7.02, 73.26 2.14
WSB/EiJ f 23.61 30.24   8 10.691 1.2808 2.24, 84.25 0.16
WSB/EiJ m 5.1887 3.6237   8 1.2812 0.6984 1.05, 11.54 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 21.6 7.3114 36.0373 7.1627
129S1/SvImJ m 17.57 8.4425 34.2408 0.8992
A/J f 29.9311 6.8933 43.5428 16.3195
A/J m 19.9311 6.8933 33.5428 6.3195
C57BL/6J f 31.705 7.3114 46.1423 17.2677
C57BL/6J m 55.8414 7.8163 71.2756 40.4073
CAST/EiJ f 19.3763 7.3114 33.8136 4.9389
CAST/EiJ m 13.09 7.3114 27.5273 -1.3473
CC002/UncJ f 6.4767 11.9395 30.0527 -17.0994
CC002/UncJ m 7.35 11.9395 30.9261 -16.2261
CC004/TauUncJ f 22.226 9.2483 40.4879 3.9641
CC004/TauUncJ m 9.27 6.8933 22.8817 -4.3417
CC006/TauUncJ f 31.29 11.9395 54.8661 7.7139
CC006/TauUncJ m 19.99 11.9395 43.5661 -3.5861
CC011/UncJ f 49.135 14.6229 78.0097 20.2603
CC011/UncJ m 14.525 14.6229 43.3997 -14.3497
CC012/GeniUncJ f 8.9633 11.9395 32.5394 -14.6127
CC012/GeniUncJ m 28.27 11.9395 51.8461 4.6939
CC028/GeniUncJ f 4.47 11.9395 28.0461 -19.1061
CC028/GeniUncJ m 3.74 11.9395 27.3161 -19.8361
CC032/GeniUncJ f 4.0733 11.9395 27.6494 -19.5027
CC032/GeniUncJ m 12.03 11.9395 35.6061 -11.5461
CC041/TauUncJ f 7.0544 6.8933 20.6661 -6.5572
CC041/TauUncJ m 3.4644 6.8933 17.0761 -10.1472
CC061/GeniUncJ f 2.62 14.6229 31.4947 -26.2547
CC061/GeniUncJ m 43.3267 11.9395 66.9027 19.7506
NOD/ShiLtJ f 6.96 8.4425 23.6308 -9.7108
NOD/ShiLtJ m 7.935 8.4425 24.6058 -8.7358
NZO/HlLtJ f 21.5489 6.8933 35.1605 7.9372
NZO/HlLtJ m 16.5111 6.8933 30.1228 2.8995
PWK/PhJ f 72.8238 7.3114 87.2611 58.3864
PWK/PhJ m 54.1822 6.8933 67.7939 40.5706
WSB/EiJ f 23.61 7.3114 38.0473 9.1727
WSB/EiJ m 5.1888 7.3114 19.6261 -9.2486


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 19.585 5.5842 30.6117 8.5583
A/J both 24.9311 4.8743 34.556 15.3062
C57BL/6J both 43.7732 5.3514 54.3403 33.2062
CAST/EiJ both 16.2331 5.17 26.4419 6.0244
CC002/UncJ both 6.9133 8.4425 23.5841 -9.7575
CC004/TauUncJ both 15.748 5.7673 27.1363 4.3597
CC006/TauUncJ both 25.64 8.4425 42.3108 8.9692
CC011/UncJ both 31.83 10.3399 52.2475 11.4125
CC012/GeniUncJ both 18.6167 8.4425 35.2875 1.9459
CC028/GeniUncJ both 4.105 8.4425 20.7758 -12.5658
CC032/GeniUncJ both 8.0517 8.4425 24.7225 -8.6191
CC041/TauUncJ both 5.2594 4.8743 14.8843 -4.3654
CC061/GeniUncJ both 22.9733 9.439 41.6119 4.3348
NOD/ShiLtJ both 7.4475 5.9698 19.2355 -4.3405
NZO/HlLtJ both 19.03 4.8743 28.6549 9.4051
PWK/PhJ both 63.503 5.0243 73.4241 53.5819
WSB/EiJ both 14.3994 5.17 24.6081 4.1906




  GWAS USING LINEAR MIXED MODELS