Project measure / variable:   CSNA02   EtOH_adj_d3

ID, description, units MPD:62225   EtOH_adj_d3   ethanol consumption adjusted per kg body weight 'drinking in the dark'   [g/kg]  day 3  
ethanol study
Data set, strains CSNA02   inbred   18 strains     sex: both     age: 16-39wks
Procedure bottle choice test
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  STRAIN COMPARISON PLOT
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CSNA02 - ethanol consumption adjusted per kg body weight 'drinking in the dark' day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains18 strains
Mean of the strain means3.6659   g/kg 2.7528   g/kg
Median of the strain means2.4375   g/kg 1.3689   g/kg
SD of the strain means± 5.091 ± 3.4588
Coefficient of variation (CV)1.3888 1.2565
Min–max range of strain means0.0   –   21.606   g/kg 0.0   –   11.713   g/kg
Mean sample size per strain5.4   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 114.4668 114.4668 6.7936 0.01
strain 16 3748.3299 234.2706 13.904 < 0.0001
sex:strain 16 617.4553 38.591 2.2904 0.0047
Residuals 163 2746.4138 16.8492


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.5325 1.6641   8 0.58835 1.0859 -0.42
129S1/SvImJ m 2.1517 3.5893   6 1.4653 1.6681 -0.17
A/J f 4.0467 5.2891   9 1.763 1.307 0.07
A/J m 3.7344 6.4646   9 2.1549 1.7311 0.28
C57BL/6J f 6.7462 5.3777   8 1.9013 0.7971 0.61
C57BL/6J m 8.8443 3.6065   7 1.3631 0.4078 3.97, 13.67 1.76
CAST/EiJ f 3.64 7.3615   8 2.6027 2.0224 0.3, 21.8 -0.01
CAST/EiJ m 0.96875 1.1275   8 0.39865 1.1639 -0.52
CC002/UncJ f 2.35 3.8135   3 2.2017 1.6228 -0.26
CC002/UncJ m 0.0 0.0   3 0.0 None -0.8
CC004/TauUncJ f 3.094 6.3562   5 2.8426 2.0544 -0.11
CC004/TauUncJ m 0.32222 0.57471   9 0.19157 1.7836 -0.7
CC006/TauUncJ f 6.1633 5.4786   3 3.1631 0.8889 0.49
CC006/TauUncJ m 5.4433 8.8289   3 5.0973 1.622 0.78
CC011/UncJ f 5.195 7.3468   2   5.195 1.4142 0.3
CC011/UncJ m 1.63 2.3052   2   1.63 1.4142 -0.32
CC012/GeniUncJ f 0.0 0.0   3 0.0 None -0.72
CC012/GeniUncJ m 0.0 0.0   3 0.0 None -0.8
CC025/GeniUncJ f 0.0 0.0   1   0.0 None -0.72
CC025/GeniUncJ m 0.0 0.0   1   0.0 None -0.8
CC028/GeniUncJ f 0.0 0.0   3 0.0 None -0.72
CC028/GeniUncJ m 3.18 5.5079   3 3.18 1.7321 0.12
CC032/GeniUncJ f 0.27667 0.4792   3 0.27667 1.7321 -0.67
CC032/GeniUncJ m 0.12 0.20785   3 0.12 1.7321 -0.76
CC041/TauUncJ f 0.19111 0.42885   9 0.14295 2.244 -0.68
CC041/TauUncJ m 0.08556 0.13648   9 0.04549 1.5953 -0.77
CC061/GeniUncJ f 0.0 0.0   2   0.0 None -0.72
CC061/GeniUncJ m 7.57 6.5572   3 3.7858 0.8662 1.39
NOD/ShiLtJ f 2.525 2.7247   6 1.1124 1.0791 -0.22
NOD/ShiLtJ m 1.6583 1.8964   6 0.7742 1.1436 -0.32
NZO/HlLtJ f 1.6167 1.8057   9 0.6019 1.1169 -0.4
NZO/HlLtJ m 1.1078 1.9742   9 0.65807 1.7821 -0.48
PWK/PhJ f 21.606 3.2045   8 1.1329 0.1483 17.1, 25.04 3.52
PWK/PhJ m 11.713 4.3972   9 1.4657 0.3754 2.94, 17.17 2.59
WSB/EiJ f 7.0025 8.2493   8 2.9166 1.178 0.15, 22.91 0.66
WSB/EiJ m 1.0213 0.66604   8 0.23548 0.6522 -0.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.5325 1.4513 4.3982 -1.3332
129S1/SvImJ m 2.1517 1.6758 5.4607 -1.1573
A/J f 4.0467 1.3683 6.7485 1.3449
A/J m 3.7344 1.3683 6.4362 1.0326
C57BL/6J f 6.7462 1.4513 9.6119 3.8806
C57BL/6J m 8.8443 1.5515 11.9078 5.7807
CAST/EiJ f 3.64 1.4513 6.5057 0.7743
CAST/EiJ m 0.9688 1.4513 3.8344 -1.8969
CC002/UncJ f 2.35 2.3699 7.0296 -2.3296
CC002/UncJ m 0.0 2.3699 4.6796 -4.6796
CC004/TauUncJ f 3.094 1.8357 6.7188 -0.5308
CC004/TauUncJ m 0.3222 1.3683 3.024 -2.3796
CC006/TauUncJ f 6.1633 2.3699 10.843 1.4837
CC006/TauUncJ m 5.4433 2.3699 10.123 0.7637
CC011/UncJ f 5.195 2.9025 10.9264 -0.5364
CC011/UncJ m 1.63 2.9025 7.3614 -4.1014
CC012/GeniUncJ f 0.0 2.3699 4.6796 -4.6796
CC012/GeniUncJ m 0.0 2.3699 4.6796 -4.6796
CC028/GeniUncJ f 0.0 2.3699 4.6796 -4.6796
CC028/GeniUncJ m 3.18 2.3699 7.8596 -1.4996
CC032/GeniUncJ f 0.2767 2.3699 4.9563 -4.403
CC032/GeniUncJ m 0.12 2.3699 4.7996 -4.5596
CC041/TauUncJ f 0.1911 1.3683 2.8929 -2.5107
CC041/TauUncJ m 0.0856 1.3683 2.7874 -2.6162
CC061/GeniUncJ f 0.0 2.9025 5.7314 -5.7314
CC061/GeniUncJ m 7.57 2.3699 12.2496 2.8904
NOD/ShiLtJ f 2.525 1.6758 5.834 -0.784
NOD/ShiLtJ m 1.6583 1.6758 4.9673 -1.6507
NZO/HlLtJ f 1.6167 1.3683 4.3185 -1.0851
NZO/HlLtJ m 1.1078 1.3683 3.8096 -1.594
PWK/PhJ f 21.6063 1.4513 24.4719 18.7406
PWK/PhJ m 11.7133 1.3683 14.4151 9.0115
WSB/EiJ f 7.0025 1.4513 9.8682 4.1368
WSB/EiJ m 1.0212 1.4513 3.8869 -1.8444


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.8421 1.1084 4.0308 -0.3466
A/J both 3.8906 0.9675 5.801 1.9801
C57BL/6J both 7.7953 1.0622 9.8927 5.6978
CAST/EiJ both 2.3044 1.0262 4.3307 0.278
CC002/UncJ both 1.175 1.6758 4.484 -2.134
CC004/TauUncJ both 1.7081 1.1448 3.9686 -0.5524
CC006/TauUncJ both 5.8033 1.6758 9.1123 2.4943
CC011/UncJ both 3.4125 2.0524 7.4652 -0.6402
CC012/GeniUncJ both 0.0 1.6758 3.309 -3.309
CC028/GeniUncJ both 1.59 1.6758 4.899 -1.719
CC032/GeniUncJ both 0.1983 1.6758 3.5073 -3.1107
CC041/TauUncJ both 0.1383 0.9675 2.0488 -1.7721
CC061/GeniUncJ both 3.785 1.8736 7.4846 0.0854
NOD/ShiLtJ both 2.0917 1.1849 4.4315 -0.2482
NZO/HlLtJ both 1.3622 0.9675 3.2727 -0.5482
PWK/PhJ both 16.6598 0.9973 18.629 14.6905
WSB/EiJ both 4.0119 1.0262 6.0382 1.9855




  GWAS USING LINEAR MIXED MODELS