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Project measure / variable:   CSNA02   EtOH_adj_d2

ID, description, units MPD:62224   EtOH_adj_d2   ethanol consumption adjusted per kg body weight 'drinking in the dark'   [g/kg]  day 2  
ethanol study
Data set, strains CSNA02   inbred   18 strains     sex: both     age: 16-39wks
Procedure bottle choice test
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  STRAIN COMPARISON PLOT
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CSNA02 - ethanol consumption adjusted per kg body weight 'drinking in the dark' day 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains18 strains
Mean of the strain means3.5257   g/kg 2.7808   g/kg
Median of the strain means2.411   g/kg 1.4754   g/kg
SD of the strain means± 4.7933 ± 3.5558
Coefficient of variation (CV)1.3595 1.2787
Min–max range of strain means0.0   –   18.775   g/kg 0.0   –   11.989   g/kg
Mean sample size per strain5.4   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 55.9048 55.9048 3.4279 0.0659
strain 16 3410.0426 213.1277 13.0682 < 0.0001
sex:strain 16 555.9724 34.7483 2.1306 0.0093
Residuals 162 2642.0443 16.3089


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.7888 3.0968   8 1.0949 1.1104 -0.15
129S1/SvImJ m 1.8917 2.7526   6 1.1237 1.4551 -0.25
A/J f 2.7367 3.3314   9 1.1105 1.2173 -0.16
A/J m 3.4778 3.9467   9 1.3156 1.1348 0.2
C57BL/6J f 4.1114 4.1799   7 1.5798 1.0166 0.01, 11.53 0.12
C57BL/6J m 8.6171 9.1323   7 3.4517 1.0598 1.64
CAST/EiJ f 2.3387 2.423   8 0.85667 1.036 0.56, 7.88 -0.25
CAST/EiJ m 1.4575 3.106   8 1.0981 2.131 -0.37
CC002/UncJ f 0.04333 0.07506   3 0.04333 1.7321 -0.73
CC002/UncJ m 0.06333 0.1097   3 0.06333 1.7321 -0.76
CC004/TauUncJ f 3.062 6.2446   5 2.7926 2.0394 -0.1
CC004/TauUncJ m 0.12778 0.21423   9 0.07141 1.6766 -0.75
CC006/TauUncJ f 8.5033 7.4555   3 4.3044 0.8768 0.21, 14.65 1.04
CC006/TauUncJ m 4.2033 7.2804   3 4.2033 1.7321 0.4
CC011/UncJ f 5.79 6.4347   2   4.55 1.1113 1.24, 10.34 0.47
CC011/UncJ m 3.58 5.0629   2   3.58 1.4142 0.22
CC012/GeniUncJ f 0.0 0.0   3 0.0 None -0.74
CC012/GeniUncJ m 0.0 0.0   3 0.0 None -0.78
CC025/GeniUncJ f 0.77 0.0   1   0.0 0.0 0.77, 0.77 -0.57
CC025/GeniUncJ m 0.0 0.0   1   0.0 None -0.78
CC028/GeniUncJ f 0.0 0.0   3 0.0 None -0.74
CC028/GeniUncJ m 0.05333 0.09238   3 0.05333 1.7321 -0.77
CC032/GeniUncJ f 0.29333 0.50807   3 0.29333 1.7321 -0.67
CC032/GeniUncJ m 0.21333 0.28729   3 0.16586 1.3467 -0.72
CC041/TauUncJ f 0.0 0.0   9 0.0 None -0.74
CC041/TauUncJ m 0.05333 0.1077   9 0.0359 2.0194 -0.77
CC061/GeniUncJ f 0.645 0.91217   2   0.645 1.4142 -0.6
CC061/GeniUncJ m 8.6967 7.6421   3 4.4121 0.8787 1.66
NOD/ShiLtJ f 2.4833 3.475   6 1.4187 1.3993 -0.22
NOD/ShiLtJ m 1.4933 2.1083   6 0.86073 1.4118 -0.36
NZO/HlLtJ f 1.0956 0.98732   9 0.32911 0.9012 -0.51
NZO/HlLtJ m 1.24 1.1276   9 0.37587 0.9094 0.24, 2.88 -0.43
PWK/PhJ f 18.775 5.9147   8 2.0912 0.315 8.37, 26.72 3.18
PWK/PhJ m 11.989 3.9267   9 1.3089 0.3275 3.68, 16.59 2.59
WSB/EiJ f 10.026 7.5052   8 2.6535 0.7486 1.36
WSB/EiJ m 2.8975 5.1777   8 1.8306 1.787 0.23, 15.59 0.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.7888 1.4278 5.6083 -0.0308
129S1/SvImJ m 1.8917 1.6487 5.1473 -1.364
A/J f 2.7367 1.3461 5.3949 0.0784
A/J m 3.4778 1.3461 6.136 0.8195
C57BL/6J f 4.1114 1.5264 7.1256 1.0973
C57BL/6J m 8.6171 1.5264 11.6313 5.603
CAST/EiJ f 2.3387 1.4278 5.1583 -0.4808
CAST/EiJ m 1.4575 1.4278 4.277 -1.362
CC002/UncJ f 0.0433 2.3316 4.6476 -4.5609
CC002/UncJ m 0.0633 2.3316 4.6676 -4.5409
CC004/TauUncJ f 3.062 1.806 6.6284 -0.5044
CC004/TauUncJ m 0.1278 1.3461 2.786 -2.5305
CC006/TauUncJ f 8.5033 2.3316 13.1076 3.8991
CC006/TauUncJ m 4.2033 2.3316 8.8076 -0.4009
CC011/UncJ f 5.79 2.8556 11.429 0.151
CC011/UncJ m 3.58 2.8556 9.219 -2.059
CC012/GeniUncJ f 0.0 2.3316 4.6042 -4.6042
CC012/GeniUncJ m 0.0 2.3316 4.6042 -4.6042
CC028/GeniUncJ f 0.0 2.3316 4.6042 -4.6042
CC028/GeniUncJ m 0.0533 2.3316 4.6576 -4.5509
CC032/GeniUncJ f 0.2933 2.3316 4.8976 -4.3109
CC032/GeniUncJ m 0.2133 2.3316 4.8176 -4.3909
CC041/TauUncJ f 0.0 1.3461 2.6583 -2.6583
CC041/TauUncJ m 0.0533 1.3461 2.7116 -2.6049
CC061/GeniUncJ f 0.645 2.8556 6.284 -4.994
CC061/GeniUncJ m 8.6967 2.3316 13.3009 4.0924
NOD/ShiLtJ f 2.4833 1.6487 5.739 -0.7723
NOD/ShiLtJ m 1.4933 1.6487 4.749 -1.7623
NZO/HlLtJ f 1.0956 1.3461 3.7538 -1.5627
NZO/HlLtJ m 1.24 1.3461 3.8983 -1.4183
PWK/PhJ f 18.775 1.4278 21.5945 15.9555
PWK/PhJ m 11.9889 1.3461 14.6471 9.3306
WSB/EiJ f 10.0263 1.4278 12.8458 7.2067
WSB/EiJ m 2.8975 1.4278 5.717 0.078


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.3402 1.0905 4.4936 0.1868
A/J both 3.1072 0.9519 4.9869 1.2276
C57BL/6J both 6.3643 1.0793 8.4956 4.2329
CAST/EiJ both 1.8981 1.0096 3.8918 -0.0956
CC002/UncJ both 0.0533 1.6487 3.309 -3.2023
CC004/TauUncJ both 1.5949 1.1263 3.8189 -0.6292
CC006/TauUncJ both 6.3533 1.6487 9.609 3.0977
CC011/UncJ both 4.685 2.0192 8.6724 0.6976
CC012/GeniUncJ both 0.0 1.6487 3.2557 -3.2557
CC028/GeniUncJ both 0.0267 1.6487 3.2823 -3.229
CC032/GeniUncJ both 0.2533 1.6487 3.509 -3.0023
CC041/TauUncJ both 0.0267 0.9519 1.9063 -1.853
CC061/GeniUncJ both 4.6708 1.8433 8.3108 1.0309
NOD/ShiLtJ both 1.9883 1.1658 4.2904 -0.3138
NZO/HlLtJ both 1.1678 0.9519 3.0474 -0.7119
PWK/PhJ both 15.3819 0.9812 17.3195 13.4444
WSB/EiJ both 6.4619 1.0096 8.4556 4.4682




  GWAS USING LINEAR MIXED MODELS