Project measure / variable:   CSNA02   EtOH_adj_d1

ID, description, units MPD:62223   EtOH_adj_d1   ethanol consumption adjusted per kg body weight 'drinking in the dark'   [g/kg]  day 1  
ethanol study
Data set, strains CSNA02   inbred   18 strains     sex: both     age: 16-39wks
Procedure bottle choice test
Ontology mappings

  STRAIN COMPARISON PLOT
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CSNA02 - ethanol consumption adjusted per kg body weight 'drinking in the dark' day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains18 strains
Mean of the strain means3.9478   g/kg 3.3235   g/kg
Median of the strain means2.8013   g/kg 1.6443   g/kg
SD of the strain means± 4.1107 ± 3.7899
Coefficient of variation (CV)1.0413 1.1403
Min–max range of strain means0.0   –   14.453   g/kg 0.0   –   11.436   g/kg
Mean sample size per strain5.4   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17.2662 17.2662 1.7964 0.182
strain 16 2715.5882 169.7243 17.6584 < 0.0001
sex:strain 16 231.5628 14.4727 1.5058 0.1032
Residuals 162 1557.0666 9.6115


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.4038 1.5367   8 0.54331 1.0947 -0.62
129S1/SvImJ m 3.835 5.2864   6 2.1582 1.3785 0.13
A/J f 2.4033 3.8987   9 1.2996 1.6222 -0.38
A/J m 3.6089 3.0977   9 1.0326 0.8584 0.5, 9.7 0.08
C57BL/6J f 7.89 4.1899   8 1.4814 0.531 1.29, 13.22 0.96
C57BL/6J m 9.5429 3.3013   7 1.2478 0.3459 5.2, 14.13 1.64
CAST/EiJ f 2.5525 2.5848   8 0.91388 1.0127 0.96, 8.85 -0.34
CAST/EiJ m 1.41 1.2269   8 0.43377 0.8701 0.03, 3.74 -0.5
CC002/UncJ f 0.60333 0.78437   3 0.45286 1.3001 -0.81
CC002/UncJ m 0.85 1.4722   3 0.85 1.7321 -0.65
CC004/TauUncJ f 1.492 0.72216   5 0.32296 0.484 0.58, 2.44 -0.6
CC004/TauUncJ m 0.50778 0.69692   9 0.23231 1.3725 -0.74
CC006/TauUncJ f 11.923 1.8634   3 1.0759 0.1563 10.53, 14.04 1.94
CC006/TauUncJ m 10.033 4.9743   3 2.8719 0.4958 4.51, 14.16 1.77
CC011/UncJ f 6.45 3.7335   2   2.64 0.5788 3.81, 9.09 0.61
CC011/UncJ m 1.35 1.9092   2   1.35 1.4142 -0.52
CC012/GeniUncJ f 0.06333 0.1097   3 0.06333 1.7321 -0.94
CC012/GeniUncJ m 0.06667 0.11547   3 0.06667 1.7321 -0.86
CC025/GeniUncJ f 4.14 0.0   1   0.0 0.0 4.14, 4.14 0.05
CC025/GeniUncJ m 0.0 0.0   1   0.0 None -0.88
CC028/GeniUncJ f 0.0 0.0   3 0.0 None -0.96
CC028/GeniUncJ m 0.03667 0.06351   3 0.03667 1.7321 -0.87
CC032/GeniUncJ f 3.68 2.9829   3 1.7222 0.8106 1.81, 7.12 -0.07
CC032/GeniUncJ m 1.23 2.1304   3 1.23 1.7321 -0.55
CC041/TauUncJ f 0.48556 0.70125   9 0.23375 1.4442 -0.84
CC041/TauUncJ m 0.39667 0.62759   9 0.2092 1.5822 -0.77
CC061/GeniUncJ f 0.345 0.4879   2   0.345 1.4142 -0.88
CC061/GeniUncJ m 8.19 7.2064   3 4.1606 0.8799 1.28
NOD/ShiLtJ f 6.5517 5.8278   6 2.3792 0.8895 1.01, 14.0 0.63
NOD/ShiLtJ m 3.3683 2.5593   6 1.0448 0.7598 0.01
NZO/HlLtJ f 3.05 1.3925   9 0.46417 0.4566 1.52, 5.39 -0.22
NZO/HlLtJ m 2.0833 1.2234   9 0.40779 0.5872 0.47, 4.55 -0.33
PWK/PhJ f 14.453 3.1896   8 1.1277 0.2207 8.71, 17.34 2.56
PWK/PhJ m 11.436 6.5437   8 2.3136 0.5722 1.63, 19.8 2.14
WSB/EiJ f 3.5737 3.8963   8 1.3775 1.0902 -0.09
WSB/EiJ m 1.8787 1.9236   8 0.68009 1.0239 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.4037 1.0961 3.5682 -0.7607
129S1/SvImJ m 3.835 1.2657 6.3343 1.3357
A/J f 2.4033 1.0334 4.444 0.3626
A/J m 3.6089 1.0334 5.6496 1.5682
C57BL/6J f 7.89 1.0961 10.0545 5.7255
C57BL/6J m 9.5429 1.1718 11.8568 7.2289
CAST/EiJ f 2.5525 1.0961 4.717 0.388
CAST/EiJ m 1.41 1.0961 3.5745 -0.7545
CC002/UncJ f 0.6033 1.7899 4.1379 -2.9313
CC002/UncJ m 0.85 1.7899 4.3846 -2.6846
CC004/TauUncJ f 1.492 1.3865 4.2299 -1.2459
CC004/TauUncJ m 0.5078 1.0334 2.5485 -1.5329
CC006/TauUncJ f 11.9233 1.7899 15.4579 8.3887
CC006/TauUncJ m 10.0333 1.7899 13.5679 6.4987
CC011/UncJ f 6.45 2.1922 10.779 2.121
CC011/UncJ m 1.35 2.1922 5.679 -2.979
CC012/GeniUncJ f 0.0633 1.7899 3.5979 -3.4713
CC012/GeniUncJ m 0.0667 1.7899 3.6013 -3.4679
CC028/GeniUncJ f 0.0 1.7899 3.5346 -3.5346
CC028/GeniUncJ m 0.0367 1.7899 3.5713 -3.4979
CC032/GeniUncJ f 3.68 1.7899 7.2146 0.1454
CC032/GeniUncJ m 1.23 1.7899 4.7646 -2.3046
CC041/TauUncJ f 0.4856 1.0334 2.5263 -1.5551
CC041/TauUncJ m 0.3967 1.0334 2.4374 -1.644
CC061/GeniUncJ f 0.345 2.1922 4.674 -3.984
CC061/GeniUncJ m 8.19 1.7899 11.7246 4.6554
NOD/ShiLtJ f 6.5517 1.2657 9.051 4.0523
NOD/ShiLtJ m 3.3683 1.2657 5.8677 0.869
NZO/HlLtJ f 3.05 1.0334 5.0907 1.0093
NZO/HlLtJ m 2.0833 1.0334 4.124 0.0426
PWK/PhJ f 14.4525 1.0961 16.617 12.288
PWK/PhJ m 11.4363 1.0961 13.6007 9.2718
WSB/EiJ f 3.5737 1.0961 5.7382 1.4093
WSB/EiJ m 1.8787 1.0961 4.0432 -0.2857


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.6194 0.8372 4.2725 0.9662
A/J both 3.0061 0.7307 4.4491 1.5631
C57BL/6J both 8.7164 0.8023 10.3007 7.1322
CAST/EiJ both 1.9813 0.7751 3.5118 0.4507
CC002/UncJ both 0.7267 1.2657 3.226 -1.7727
CC004/TauUncJ both 0.9999 0.8646 2.7073 -0.7075
CC006/TauUncJ both 10.9783 1.2657 13.4777 8.479
CC011/UncJ both 3.9 1.5501 6.9611 0.8389
CC012/GeniUncJ both 0.065 1.2657 2.5643 -2.4343
CC028/GeniUncJ both 0.0183 1.2657 2.5177 -2.481
CC032/GeniUncJ both 2.455 1.2657 4.9543 -0.0443
CC041/TauUncJ both 0.4411 0.7307 1.8841 -1.0019
CC061/GeniUncJ both 4.2675 1.4151 7.0618 1.4732
NOD/ShiLtJ both 4.96 0.895 6.7273 3.1927
NZO/HlLtJ both 2.5667 0.7307 4.0097 1.1237
PWK/PhJ both 12.9444 0.7751 14.4749 11.4138
WSB/EiJ both 2.7262 0.7751 4.2568 1.1957




  GWAS USING LINEAR MIXED MODELS