Phenotype measure:   McMullan7   VCO2_d_end_HIIT

ID, description, units MPD:61619   VCO2_d_end_HIIT   mean carbon dioxide production after 4 wks of treatment, during day   [mL/h]  high intensity group
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan7 - mean carbon dioxide production after 4 wks of treatment, during day high intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means3234   mL/h 2749   mL/h
Median of the strain means3296   mL/h 2790   mL/h
SD of the strain means± 179 ± 254
Coefficient of variation (CV)0.0553 0.0926
Min–max range of strain means2971   –   3372   mL/h 2403   –   3012   mL/h
Mean sample size per strain11.8   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5157631.0992 5157631.0992 26.4559 < 0.0001
strain 3 2976907.5916 992302.5305 5.09 0.0029
sex:strain 3 120405.8338 40135.2779 0.2059 0.892
Residuals 75 14621425.0483 194952.334


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 3372.0 529.0   14 141.0 0.157 2326.0, 4417.0 0.77
CC002/Unc m 3012.0 350.0   6 143.0 0.116 2647.0, 3396.0 1.03
CC013/GeniUnc f 3301.0 523.0   4 261.0 0.158 2608.0, 3862.0 0.37
CC013/GeniUnc m 2758.0 322.0   8 114.0 0.117 2313.0, 3130.0 0.04
CC027/GeniUnc f 3292.0 488.0   14 130.0 0.148 1936.0, 3849.0 0.32
CC027/GeniUnc m 2822.0 471.0   11 142.0 0.167 1905.0, 3564.0 0.29
CC037/TauUnc f 2971.0 433.0   15 112.0 0.146 2453.0, 3885.0 -1.47
CC037/TauUnc m 2403.0 298.0   11 90.0 0.124 1979.0, 3094.0 -1.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 3372.4536 118.0049 3607.5315 3137.3757
CC002/Unc m 3012.5 180.2555 3371.5874 2653.4126
CC013/GeniUnc f 3301.4 220.767 3741.1905 2861.6095
CC013/GeniUnc m 2758.1 156.1059 3069.0788 2447.1212
CC027/GeniUnc f 3292.3464 118.0049 3527.4243 3057.2685
CC027/GeniUnc m 2822.4455 133.1275 3087.6491 2557.2418
CC037/TauUnc f 2971.3367 114.0036 3198.4435 2744.2298
CC037/TauUnc m 2402.5909 133.1275 2667.7945 2137.3873


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 3192.4768 107.7233 3407.0726 2977.881
CC013/GeniUnc both 3029.75 135.1916 3299.0656 2760.4344
CC027/GeniUnc both 3057.3959 88.9496 3234.5926 2880.1993
CC037/TauUnc both 2686.9638 87.6353 2861.5422 2512.3854




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA