Phenotype measure:   McMullan7   VCO2_d_end_MICT

ID, description, units MPD:61618   VCO2_d_end_MICT   mean carbon dioxide production after 4 wks of treatment, during day   [mL/h]  moderate intensity group
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan7 - mean carbon dioxide production after 4 wks of treatment, during day moderate intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means3144   mL/h 2716   mL/h
Median of the strain means3230   mL/h 2772   mL/h
SD of the strain means± 272 ± 212
Coefficient of variation (CV)0.0866 0.0781
Min–max range of strain means2748   –   3369   mL/h 2429   –   2892   mL/h
Mean sample size per strain13.5   mice 9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4043540.2843 4043540.2843 21.1277 < 0.0001
strain 3 4513940.9479 1504646.9826 7.8619 0.0001
sex:strain 3 177419.3456 59139.7819 0.309 0.8188
Residuals 84 16076381.7625 191385.4972


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 3220.0 468.0   16 117.0 0.145 2260.0, 3873.0 0.28
CC002/Unc m 2859.0 717.0   8 254.0 0.251 1912.0, 4062.0 0.67
CC013/GeniUnc f 3239.0 546.0   8 193.0 0.168 2319.0, 3807.0 0.35
CC013/GeniUnc m 2684.0 449.0   8 159.0 0.167 2069.0, 3326.0 -0.15
CC027/GeniUnc f 3369.0 369.0   15 95.4 0.11 2749.0, 4081.0 0.83
CC027/GeniUnc m 2892.0 322.0   11 96.9 0.111 2402.0, 3371.0 0.83
CC037/TauUnc f 2748.0 344.0   15 88.9 0.125 2388.0, 3590.0 -1.45
CC037/TauUnc m 2429.0 329.0   11 99.3 0.136 1983.0, 3032.0 -1.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 3219.9531 109.3691 3437.4455 3002.4607
CC002/Unc m 2859.15 154.6712 3166.7307 2551.5693
CC013/GeniUnc f 3239.25 154.6712 3546.8307 2931.6693
CC013/GeniUnc m 2684.0375 154.6712 2991.6182 2376.4568
CC027/GeniUnc f 3368.85 112.9559 3593.4752 3144.2248
CC027/GeniUnc m 2891.8045 131.9041 3154.1102 2629.4989
CC037/TauUnc f 2747.5033 112.9559 2972.1285 2522.8782
CC037/TauUnc m 2428.7773 131.9041 2691.083 2166.4716


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 3039.5516 94.7164 3227.9055 2851.1976
CC013/GeniUnc both 2961.6438 109.3691 3179.1361 2744.1514
CC027/GeniUnc both 3130.3273 86.8299 3302.998 2957.6565
CC037/TauUnc both 2588.1403 86.8299 2760.811 2415.4696




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA