Phenotype measure:   McMullan7   VCO2_d_end_ctrl

ID, description, units MPD:61617   VCO2_d_end_ctrl   mean carbon dioxide production after 4 wks of treatment, during day   [mL/h]  no exercise group
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan7 - mean carbon dioxide production after 4 wks of treatment, during day no exercise group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means3013   mL/h 2680   mL/h
Median of the strain means3136   mL/h 2696   mL/h
SD of the strain means± 277 ± 223
Coefficient of variation (CV)0.0918 0.0832
Min–max range of strain means2600   –   3180   mL/h 2431   –   2895   mL/h
Mean sample size per strain7.8   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1892422.3364 1892422.3364 9.8077 0.0028
strain 3 2530820.883 843606.961 4.3721 0.0078
sex:strain 3 325264.186 108421.3953 0.5619 0.6424
Residuals 55 10612391.9378 192952.5807


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 3180.0 728.0   8 257.0 0.229 2154.0, 4029.0 0.6
CC002/Unc m 2838.0 373.0   8 132.0 0.131 2051.0, 3366.0 0.71
CC013/GeniUnc f 3158.0 403.0   8 142.0 0.128 2633.0, 3764.0 0.52
CC013/GeniUnc m 2895.0 460.0   8 163.0 0.159 1877.0, 3204.0 0.97
CC027/GeniUnc f 3114.0 387.0   8 137.0 0.124 2521.0, 3744.0 0.37
CC027/GeniUnc m 2554.0 427.0   8 151.0 0.167 1686.0, 3016.0 -0.56
CC037/TauUnc f 2600.0 196.0   7 74.2 0.0755 2346.0, 2906.0 -1.49
CC037/TauUnc m 2431.0 328.0   8 116.0 0.135 2037.0, 3130.0 -1.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 3180.0812 155.3032 3491.3157 2868.8468
CC002/Unc m 2837.725 155.3032 3148.9595 2526.4905
CC013/GeniUnc f 3158.3812 155.3032 3469.6157 2847.1468
CC013/GeniUnc m 2895.3438 155.3032 3206.5782 2584.1093
CC027/GeniUnc f 3113.6125 155.3032 3424.847 2802.378
CC027/GeniUnc m 2554.3625 155.3032 2865.597 2243.128
CC037/TauUnc f 2599.7 166.0261 2932.4237 2266.9763
CC037/TauUnc m 2430.9625 155.3032 2742.197 2119.728


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 3008.9031 109.8159 3228.9791 2788.8271
CC013/GeniUnc both 3026.8625 109.8159 3246.9385 2806.7865
CC027/GeniUnc both 2833.9875 109.8159 3054.0635 2613.9115
CC037/TauUnc both 2515.3312 113.6703 2743.1316 2287.5309




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA