Phenotype measure:   McMullan7   VO2_n_end_HIIT

ID, description, units MPD:61613   VO2_n_end_HIIT   mean oxygen consumption after 4 wks of treatment, during night   [mL/h]  high intensity group   measure
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan7 - mean oxygen consumption after 4 wks of treatment, during night high intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means4337   mL/h 3752   mL/h
Median of the strain means4397   mL/h 3808   mL/h
SD of the strain means± 328 ± 287
Coefficient of variation (CV)0.0756 0.0764
Min–max range of strain means3900   –   4655   mL/h 3368   –   4023   mL/h
Mean sample size per strain11.8   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4709278.9865 4709278.9865 29.2627 < 0.0001
strain 3 5041389.9278 1680463.3093 10.4421 < 0.0001
sex:strain 3 140358.6097 46786.2032 0.2907 0.832
Residuals 75 12069836.2186 160931.1496


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 3900.0 409.0   14 109.0 0.105 3012.0, 4508.0 -1.33
CC002/Unc m 3368.0 272.0   6 111.0 0.0809 2981.0, 3746.0 -1.34
CC013/GeniUnc f 4655.0 500.0   4 250.0 0.107 4207.0, 5368.0 0.97
CC013/GeniUnc m 3907.0 295.0   8 104.0 0.0756 3699.0, 4439.0 0.54
CC027/GeniUnc f 4290.0 451.0   14 121.0 0.105 3520.0, 4883.0 -0.14
CC027/GeniUnc m 3710.0 359.0   11 108.0 0.0967 3244.0, 4258.0 -0.15
CC037/TauUnc f 4504.0 483.0   15 125.0 0.107 3915.0, 5678.0 0.51
CC037/TauUnc m 4023.0 310.0   11 93.6 0.0772 3483.0, 4421.0 0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 3900.0607 107.2151 4113.6442 3686.4772
CC002/Unc m 3367.75 163.7738 3694.0041 3041.4959
CC013/GeniUnc f 4655.4625 200.5811 5055.0406 4255.8844
CC013/GeniUnc m 3907.3187 141.8323 4189.8631 3624.7744
CC027/GeniUnc f 4289.8071 107.2151 4503.3906 4076.2237
CC027/GeniUnc m 3709.6955 120.955 3950.6501 3468.7408
CC037/TauUnc f 4503.5033 103.5796 4709.8446 4297.1621
CC037/TauUnc m 4023.1455 120.955 4264.1001 3782.1908


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 3633.9054 97.8736 3828.8795 3438.9312
CC013/GeniUnc both 4281.3906 122.8304 4526.0812 4036.7
CC027/GeniUnc both 3999.7513 80.8164 4160.7459 3838.7567
CC037/TauUnc both 4263.3244 79.6223 4421.9402 4104.7086




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA