Phenotype measure:   McMullan7   VO2_n_end_MICT

ID, description, units MPD:61612   VO2_n_end_MICT   mean oxygen consumption after 4 wks of treatment, during night   [mL/h]  moderate intensity group   measure
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan7 - mean oxygen consumption after 4 wks of treatment, during night moderate intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means4286   mL/h 3709   mL/h
Median of the strain means4310   mL/h 3779   mL/h
SD of the strain means± 219 ± 334
Coefficient of variation (CV)0.0511 0.0901
Min–max range of strain means4000   –   4524   mL/h 3242   –   4035   mL/h
Mean sample size per strain13.5   mice 9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5754781.9809 5754781.9809 43.2247 < 0.0001
strain 3 3690265.2834 1230088.4278 9.2393 < 0.0001
sex:strain 3 1068190.2379 356063.4126 2.6744 0.0524
Residuals 84 11183456.4242 133136.386


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 4000.0 470.0   16 117.0 0.117 3314.0, 4814.0 -1.31
CC002/Unc m 3242.0 161.0   8 56.9 0.0496 3021.0, 3488.0 -1.4
CC013/GeniUnc f 4524.0 399.0   8 141.0 0.0882 3971.0, 5120.0 1.09
CC013/GeniUnc m 3761.0 186.0   8 65.7 0.0494 3526.0, 4052.0 0.16
CC027/GeniUnc f 4356.0 295.0   15 76.2 0.0678 3858.0, 4794.0 0.32
CC027/GeniUnc m 3797.0 355.0   11 107.0 0.0934 3095.0, 4286.0 0.26
CC037/TauUnc f 4264.0 514.0   15 133.0 0.121 3397.0, 5317.0 -0.1
CC037/TauUnc m 4035.0 126.0   11 38.0 0.0312 3826.0, 4204.0 0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 3999.6219 91.2196 4181.0221 3818.2216
CC002/Unc m 3241.9938 129.0041 3498.5325 2985.455
CC013/GeniUnc f 4523.8 129.0041 4780.3387 4267.2613
CC013/GeniUnc m 3761.3188 129.0041 4017.8575 3504.78
CC027/GeniUnc f 4356.1667 94.2112 4543.5161 4168.8173
CC027/GeniUnc m 3797.1364 110.015 4015.9133 3578.3594
CC037/TauUnc f 4263.6633 94.2112 4451.0127 4076.3139
CC037/TauUnc m 4035.4682 110.015 4254.2451 3816.6912


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 3620.8078 78.9985 3777.9051 3463.7106
CC013/GeniUnc both 4142.5594 91.2196 4323.9596 3961.1591
CC027/GeniUnc both 4076.6515 72.4208 4220.6681 3932.6349
CC037/TauUnc both 4149.5658 72.4208 4293.5824 4005.5491




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA