Phenotype measure:   McMullan7   VO2_n_end_ctrl

ID, description, units MPD:61611   VO2_n_end_ctrl   mean oxygen consumption after 4 wks of treatment, during night   [mL/h]  no exercise group   measure
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan7 - mean oxygen consumption after 4 wks of treatment, during night no exercise group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means4270   mL/h 3864   mL/h
Median of the strain means4252   mL/h 3788   mL/h
SD of the strain means± 88.8 ± 236
Coefficient of variation (CV)0.0208 0.0611
Min–max range of strain means4188   –   4391   mL/h 3671   –   4208   mL/h
Mean sample size per strain7.8   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2594998.0033 2594998.0033 16.0864 0.0002
strain 3 715479.6413 238493.2138 1.4784 0.2305
sex:strain 3 812620.0707 270873.3569 1.6791 0.1821
Residuals 55 8872410.049 161316.5463


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 4223.0 577.0   8 204.0 0.137 3512.0, 5072.0 -0.53
CC002/Unc m 3794.0 531.0   8 188.0 0.14 3003.0, 4693.0 -0.3
CC013/GeniUnc f 4391.0 333.0   8 118.0 0.0759 4002.0, 4882.0 1.36
CC013/GeniUnc m 3671.0 188.0   8 66.3 0.0511 3362.0, 3894.0 -0.82
CC027/GeniUnc f 4188.0 246.0   8 87.0 0.0588 3858.0, 4508.0 -0.93
CC027/GeniUnc m 3783.0 412.0   8 146.0 0.109 3039.0, 4294.0 -0.34
CC037/TauUnc f 4280.0 492.0   7 186.0 0.115 3584.0, 4824.0 0.11
CC037/TauUnc m 4208.0 264.0   8 93.2 0.0626 3641.0, 4525.0 1.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 4222.6437 142.002 4507.2221 3938.0654
CC002/Unc m 3794.1312 142.002 4078.7096 3509.5529
CC013/GeniUnc f 4390.9812 142.002 4675.5596 4106.4029
CC013/GeniUnc m 3671.2062 142.002 3955.7846 3386.6279
CC027/GeniUnc f 4187.8 142.002 4472.3784 3903.2216
CC027/GeniUnc m 3782.6562 142.002 4067.2346 3498.0779
CC037/TauUnc f 4280.0714 151.8065 4584.2985 3975.8444
CC037/TauUnc m 4208.4125 142.002 4492.9909 3923.8341


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 4008.3875 100.4106 4209.6148 3807.1602
CC013/GeniUnc both 4031.0937 100.4106 4232.321 3829.8665
CC027/GeniUnc both 3985.2281 100.4106 4186.4554 3784.0008
CC037/TauUnc both 4244.242 103.9348 4452.532 4035.9519




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA