Project measure / variable:   McMullan7   VO2_d_end_MICT

ID, description, units MPD:61605   VO2_d_end_MICT   mean oxygen consumption after 4 wks of treatment, during day   [mL/h]  moderate intensity group  
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan7 - mean oxygen consumption after 4 wks of treatment, during day moderate intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means3504   mL/h 3063   mL/h
Median of the strain means3480   mL/h 3066   mL/h
SD of the strain means± 192 ± 163
Coefficient of variation (CV)0.0548 0.0532
Min–max range of strain means3296   –   3761   mL/h 2863   –   3256   mL/h
Mean sample size per strain13.5   mice 9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4018713.833 4018713.833 33.5455 < 0.0001
strain 3 2121054.952 707018.3173 5.9017 0.0011
sex:strain 3 315974.1875 105324.7292 0.8792 0.4553
Residuals 84 10063122.1807 119799.0736


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 3296.0 265.0   16 66.3 0.0804 2937.0, 3940.0 -1.09
CC002/Unc m 3032.0 564.0   8 199.0 0.186 2241.0, 4104.0 -0.19
CC013/GeniUnc f 3469.0 439.0   8 155.0 0.127 2647.0, 4064.0 -0.18
CC013/GeniUnc m 2863.0 330.0   8 117.0 0.115 2497.0, 3361.0 -1.23
CC027/GeniUnc f 3761.0 370.0   15 95.6 0.0985 3085.0, 4552.0 1.34
CC027/GeniUnc m 3256.0 227.0   11 68.5 0.0698 2867.0, 3604.0 1.19
CC037/TauUnc f 3492.0 324.0   15 83.6 0.0927 2939.0, 3989.0 -0.07
CC037/TauUnc m 3100.0 277.0   11 83.5 0.0893 2656.0, 3476.0 0.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 3296.4063 86.53 3468.4807 3124.3318
CC002/Unc m 3032.25 122.3719 3275.6 2788.9
CC013/GeniUnc f 3468.9 122.3719 3712.25 3225.55
CC013/GeniUnc m 2862.675 122.3719 3106.025 2619.325
CC027/GeniUnc f 3761.42 89.3678 3939.1377 3583.7023
CC027/GeniUnc m 3256.1045 104.3591 3463.6341 3048.575
CC037/TauUnc f 3492.06 89.3678 3669.7777 3314.3423
CC037/TauUnc m 3100.1591 104.3591 3307.6886 2892.6295


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 3164.3281 74.9372 3313.3489 3015.3073
CC013/GeniUnc both 3165.7875 86.53 3337.8619 2993.7131
CC027/GeniUnc both 3508.7623 68.6976 3645.3749 3372.1496
CC037/TauUnc both 3296.1095 68.6976 3432.7222 3159.4969




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA