Project measure / variable:   McMullan7   VO2_d_end_ctrl

ID, description, units MPD:61604   VO2_d_end_ctrl   mean oxygen consumption after 4 wks of treatment, during day   [mL/h]  no exercise group  
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan7 - mean oxygen consumption after 4 wks of treatment, during day no exercise group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means3427   mL/h 3095   mL/h
Median of the strain means3358   mL/h 3106   mL/h
SD of the strain means± 160 ± 28.8
Coefficient of variation (CV)0.0466 0.00930
Min–max range of strain means3326   –   3665   mL/h 3054   –   3116   mL/h
Mean sample size per strain7.8   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1765336.6457 1765336.6457 13.6882 0.0005
strain 3 309766.0498 103255.3499 0.8006 0.4989
sex:strain 3 310003.8283 103334.6094 0.8012 0.4985
Residuals 55 7093203.9634 128967.3448


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 3363.0 566.0   8 200.0 0.168 2570.0, 3986.0 -0.4
CC002/Unc m 3116.0 186.0   8 65.6 0.0596 2818.0, 3352.0 0.72
CC013/GeniUnc f 3353.0 282.0   8 99.8 0.0842 2940.0, 3772.0 -0.46
CC013/GeniUnc m 3054.0 321.0   8 113.0 0.105 2453.0, 3399.0 -1.43
CC027/GeniUnc f 3665.0 433.0   8 153.0 0.118 3002.0, 4257.0 1.49
CC027/GeniUnc m 3097.0 403.0   8 143.0 0.13 2333.0, 3560.0 0.06
CC037/TauUnc f 3326.0 173.0   7 65.3 0.052 3118.0, 3554.0 -0.63
CC037/TauUnc m 3114.0 316.0   8 112.0 0.101 2814.0, 3761.0 0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 3362.8437 126.9682 3617.2937 3108.3938
CC002/Unc m 3115.85 126.9682 3370.2999 2861.4001
CC013/GeniUnc f 3353.2062 126.9682 3607.6562 3098.7563
CC013/GeniUnc m 3053.8438 126.9682 3308.2937 2799.3938
CC027/GeniUnc f 3664.85 126.9682 3919.2999 3410.4001
CC027/GeniUnc m 3096.725 126.9682 3351.1749 2842.2751
CC037/TauUnc f 3326.3571 135.7347 3598.3755 3054.3387
CC037/TauUnc m 3114.4687 126.9682 3368.9187 2860.0188


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 3239.3469 89.7801 3419.2701 3059.4236
CC013/GeniUnc both 3203.525 89.7801 3383.4483 3023.6017
CC027/GeniUnc both 3380.7875 89.7801 3560.7108 3200.8642
CC037/TauUnc both 3220.4129 92.9312 3406.6512 3034.1747




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA