Phenotype measure:   Kliethermes1   regression_OP

ID, description, units MPD:59944   regression_OP   residual score from regression of object preference (count) on horizontal activity in object preference task to assess novelty seeking, 10 min test   [score]
Data set, strains Kliethermes1   inbred   14 strains     sex: both     age: 8wks
Procedure hole board test
Ontology mappings

  STRAIN COMPARISON PLOT
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Kliethermes1 - residual score from regression of object preference (count) on horizontal activity in object preference task to assess novelty seeking, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means-1.02   score -0.496   score
Median of the strain means0.134   score -1.42   score
SD of the strain means± 13.2 ± 11.9
Coefficient of variation (CV)-12.9 -24.0
Min–max range of strain means-25.5   –   26.8   score -21.8   –   21.8   score
Mean sample size per strain6.3   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.7825 1.7825 0.0066 0.9354
strain 13 14487.7121 1114.4394 4.1146 < 0.0001
sex:strain 13 10384.4826 798.8064 2.9492 0.0007
Residuals 158 42794.4256 270.8508


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f -25.5 23.5   6 9.6 -0.921 -59.1, -0.937 -1.86
129S1/SvImJ m 17.6 21.8   6 8.91 1.24 -18.1, 37.7 1.52
A/J f -3.29 24.9   6 10.2 -7.57 -28.9, 23.4 -0.17
A/J m -21.8 5.22   6 2.13 -0.239 -25.9, -14.4 -1.79
AKR/J f -5.3 16.7   6 6.8 -3.14 -21.9, 16.5 -0.33
AKR/J m -15.9 12.0   6 4.9 -0.756 -35.0, -2.14 -1.29
BALB/cByJ f -20.2 15.8   5 7.08 -0.782 -43.2, 0.932 -1.46
BALB/cByJ m 5.31 11.5   6 4.68 2.16 -11.4, 19.3 0.49
BTBR T+ Itpr3tf/J f 7.94 20.2   6 8.24 2.54 -15.0, 38.5 0.68
BTBR T+ Itpr3tf/J m -7.33 12.2   6 4.97 -1.66 -24.5, 2.17 -0.57
C3H/HeJ f 26.8 12.0   6 4.89 0.448 8.04, 40.3 2.12
C3H/HeJ m 21.8 17.7   6 7.22 0.81 -3.27, 40.1 1.87
C57BL/6J f 4.24 15.2   12 4.39 3.59 -14.5, 30.6 0.4
C57BL/6J m 0.87 16.3   12 4.71 18.8 -14.4, 37.7 0.11
C57L/J f -12.4 16.1   6 6.59 -1.31 -33.9, 11.0 -0.87
C57L/J m -6.66 6.05   6 2.47 -0.908 -16.8, 0.8 -0.52
DBA/2J f 4.64 8.35   12 2.41 1.8 -8.05, 16.3 0.43
DBA/2J m 8.6 18.4   12 5.32 2.14 -16.3, 39.0 0.76
FVB/NJ f 12.1 18.7   6 7.64 1.54 -15.5, 35.6 1.0
FVB/NJ m 1.7 24.3   6 9.92 14.3 -36.0, 28.2 0.18
NOD/ShiLtJ f -6.17 5.56   5 2.49 -0.901 -13.6, 1.79 -0.39
NOD/ShiLtJ m -3.73 11.7   6 4.78 -3.14 -18.2, 10.6 -0.27
NZB/BlNJ f -0.592 26.0   6 10.6 -43.9 -47.5, 26.5 0.03
NZB/BlNJ m -8.88 15.8   6 6.46 -1.78 -34.6, 7.75 -0.7
PERA/EiJ f 2.58 14.3   5 6.41 5.56 -14.9, 19.1 0.27
PERA/EiJ m 5.18 26.4   4 13.2 5.09 -25.7, 35.8 0.48
PL/J f 0.859 9.45   6 3.86 11.0 -13.0, 9.58 0.14
PL/J m -3.71 12.3   5 5.52 -3.33 -17.5, 14.3 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f -25.5439 6.7188 -12.2737 -38.8141
129S1/SvImJ m 17.6355 6.7188 30.9057 4.3653
A/J f -3.2917 6.7188 9.9785 -16.5618
A/J m -21.8067 6.7188 -8.5365 -35.0768
AKR/J f -5.2996 6.7188 7.9706 -18.5698
AKR/J m -15.8743 6.7188 -2.6042 -29.1445
BALB/cByJ f -20.2415 7.36 -5.7048 -34.7783
BALB/cByJ m 5.3083 6.7188 18.5785 -7.9618
BTBR T+ Itpr3tf/J f 7.9412 6.7188 21.2113 -5.329
BTBR T+ Itpr3tf/J m -7.3332 6.7188 5.937 -20.6033
C3H/HeJ f 26.7527 6.7188 40.0228 13.4825
C3H/HeJ m 21.8477 6.7188 35.1178 8.5775
C57BL/6J f 4.239 4.7509 13.6224 -5.1444
C57BL/6J m 0.8695 4.7509 10.2529 -8.5139
C57L/J f -12.3619 6.7188 0.9083 -25.6321
C57L/J m -6.6625 6.7188 6.6077 -19.9327
DBA/2J f 4.6393 4.7509 14.0228 -4.7441
DBA/2J m 8.6037 4.7509 17.9871 -0.7798
FVB/NJ f 12.1272 6.7188 25.3973 -1.143
FVB/NJ m 1.7037 6.7188 14.9738 -11.5665
NOD/ShiLtJ f -6.1718 7.36 8.365 -20.7086
NOD/ShiLtJ m -3.7277 6.7188 9.5425 -16.9978
NZB/BlNJ f -0.5917 6.7188 12.6785 -13.8618
NZB/BlNJ m -8.8829 6.7188 4.3872 -22.1531
PERA/EiJ f 2.5784 7.36 17.1152 -11.9584
PERA/EiJ m 5.1817 8.2288 21.4343 -11.0708
PL/J f 0.8585 6.7188 14.1287 -12.4117
PL/J m -3.7068 7.36 10.83 -18.2436


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both -3.9542 4.7509 5.4292 -13.3376
A/J both -12.5492 4.7509 -3.1657 -21.9326
AKR/J both -10.587 4.7509 -1.2035 -19.9704
BALB/cByJ both -7.4666 4.9828 2.3748 -17.308
BTBR T+ Itpr3tf/J both 0.304 4.7509 9.6874 -9.0794
C3H/HeJ both 24.3002 4.7509 33.6836 14.9167
C57BL/6J both 2.5542 3.3594 9.1893 -4.0808
C57L/J both -9.5122 4.7509 -0.1288 -18.8956
DBA/2J both 6.6215 3.3594 13.2566 -0.0136
FVB/NJ both 6.9154 4.7509 16.2989 -2.468
NOD/ShiLtJ both -4.9497 4.9828 4.8917 -14.7912
NZB/BlNJ both -4.7373 4.7509 4.6461 -14.1207
PERA/EiJ both 3.8801 5.52 14.7826 -7.0225
PL/J both -1.4241 4.9828 8.4173 -11.2656




  GWAS USING LINEAR MIXED MODELS