Phenotype measure:   Kliethermes1   activity_OP


  STRAIN COMPARISON PLOT
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Kliethermes1 - activity (beam breaks) in object preference task to assess novelty seeking, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means2647   n 2411   n
Median of the strain means2316   n 2170   n
SD of the strain means± 1162 ± 943
Coefficient of variation (CV)0.439 0.391
Min–max range of strain means1096   –   4739   n 1188   –   4356   n
Mean sample size per strain6.5   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2231739.2842 2231739.2842 3.4228 0.0661
strain 13 157296918.6987 12099762.9768 18.5574 < 0.0001
sex:strain 13 19570014.8803 1505385.76 2.3088 0.0078
Residuals 162 105626686.8 652016.5852


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1256.0 515.0   6 210.0 0.41 270.0, 1748.0 -1.2
129S1/SvImJ m 1380.0 565.0   6 231.0 0.409 566.0, 1996.0 -1.09
A/J f 1096.0 313.0   6 128.0 0.285 592.0, 1458.0 -1.33
A/J m 1188.0 374.0   6 153.0 0.315 810.0, 1810.0 -1.3
AKR/J f 2514.0 800.0   6 327.0 0.318 1702.0, 3494.0 -0.11
AKR/J m 2885.0 739.0   6 302.0 0.256 1972.0, 3896.0 0.5
BALB/cByJ f 2691.0 737.0   5 330.0 0.274 1978.0, 3744.0 0.04
BALB/cByJ m 1407.0 535.0   6 219.0 0.38 672.0, 2250.0 -1.07
BTBR T+ Itpr3tf/J f 2117.0 684.0   6 279.0 0.323 1234.0, 3250.0 -0.46
BTBR T+ Itpr3tf/J m 2040.0 598.0   6 244.0 0.293 1284.0, 2900.0 -0.39
C3H/HeJ f 2049.0 373.0   6 152.0 0.182 1378.0, 2484.0 -0.51
C3H/HeJ m 1782.0 362.0   6 148.0 0.203 1396.0, 2392.0 -0.67
C57BL/6J f 3050.0 1204.0   12 348.0 0.395 2184.0, 6658.0 0.35
C57BL/6J m 2664.0 481.0   12 139.0 0.18 1808.0, 3444.0 0.27
C57L/J f 4059.0 446.0   6 182.0 0.11 3516.0, 4530.0 1.21
C57L/J m 3165.0 851.0   6 348.0 0.269 1552.0, 3746.0 0.8
DBA/2J f 1766.0 467.0   12 135.0 0.264 1362.0, 2838.0 -0.76
DBA/2J m 2301.0 668.0   12 193.0 0.29 1472.0, 3368.0 -0.12
FVB/NJ f 4739.0 331.0   6 135.0 0.0699 4356.0, 5270.0 1.8
FVB/NJ m 3430.0 708.0   6 289.0 0.206 2750.0, 4700.0 1.08
NOD/ShiLtJ f 4512.0 1444.0   6 589.0 0.32 2426.0, 6296.0 1.6
NOD/ShiLtJ m 3468.0 453.0   6 185.0 0.131 2958.0, 3974.0 1.12
NZB/BlNJ f 1699.0 634.0   6 259.0 0.373 922.0, 2438.0 -0.82
NZB/BlNJ m 1870.0 956.0   6 390.0 0.512 1090.0, 3662.0 -0.57
PERA/EiJ f 2104.0 630.0   6 257.0 0.3 1376.0, 3152.0 -0.47
PERA/EiJ m 1818.0 915.0   6 374.0 0.504 1024.0, 3404.0 -0.63
PL/J f 3408.0 716.0   6 292.0 0.21 2338.0, 4444.0 0.65
PL/J m 4356.0 2562.0   5 1146.0 0.588 2938.0, 8898.0 2.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1256.0 329.6505 1906.966 605.034
129S1/SvImJ m 1380.3333 329.6505 2031.2993 729.3674
A/J f 1096.0 329.6505 1746.966 445.034
A/J m 1188.0 329.6505 1838.966 537.034
AKR/J f 2513.6667 329.6505 3164.6326 1862.7007
AKR/J m 2885.3333 329.6505 3536.2993 2234.3674
BALB/cByJ f 2691.2 361.114 3404.2975 1978.1025
BALB/cByJ m 1407.3333 329.6505 2058.2993 756.3674
BTBR T+ Itpr3tf/J f 2117.0 329.6505 2767.966 1466.034
BTBR T+ Itpr3tf/J m 2040.0 329.6505 2690.966 1389.034
C3H/HeJ f 2049.3333 329.6505 2700.2993 1398.3674
C3H/HeJ m 1782.3333 329.6505 2433.2993 1131.3674
C57BL/6J f 3049.6667 233.0981 3509.9691 2589.3642
C57BL/6J m 2664.3333 233.0981 3124.6358 2204.0309
C57L/J f 4059.0 329.6505 4709.966 3408.034
C57L/J m 3165.0 329.6505 3815.966 2514.034
DBA/2J f 1765.8333 233.0981 2226.1358 1305.5309
DBA/2J m 2301.1667 233.0981 2761.4691 1840.8642
FVB/NJ f 4739.3333 329.6505 5390.2993 4088.3674
FVB/NJ m 3429.6667 329.6505 4080.6326 2778.7007
NOD/ShiLtJ f 4512.0 329.6505 5162.966 3861.034
NOD/ShiLtJ m 3468.0 329.6505 4118.966 2817.034
NZB/BlNJ f 1698.6667 329.6505 2349.6326 1047.7007
NZB/BlNJ m 1869.6667 329.6505 2520.6326 1218.7007
PERA/EiJ f 2104.0 329.6505 2754.966 1453.034
PERA/EiJ m 1818.0 329.6505 2468.966 1167.034
PL/J f 3408.0 329.6505 4058.966 2757.034
PL/J m 4356.0 361.114 5069.0975 3642.9025


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1318.1667 233.0981 1778.4691 857.8642
A/J both 1142.0 233.0981 1602.3025 681.6975
AKR/J both 2699.5 233.0981 3159.8025 2239.1975
BALB/cByJ both 2049.2667 244.4753 2532.036 1566.4974
BTBR T+ Itpr3tf/J both 2078.5 233.0981 2538.8025 1618.1975
C3H/HeJ both 1915.8333 233.0981 2376.1358 1455.5309
C57BL/6J both 2857.0 164.8252 3182.483 2531.517
C57L/J both 3612.0 233.0981 4072.3025 3151.6975
DBA/2J both 2033.5 164.8252 2358.983 1708.017
FVB/NJ both 4084.5 233.0981 4544.8025 3624.1975
NOD/ShiLtJ both 3990.0 233.0981 4450.3025 3529.6975
NZB/BlNJ both 1784.1667 233.0981 2244.4691 1323.8642
PERA/EiJ both 1961.0 233.0981 2421.3025 1500.6975
PL/J both 3882.0 244.4753 4364.7693 3399.2307




  GWAS USING LINEAR MIXED MODELS