Phenotype measure:   Kliethermes1   regression_HD

ID, description, units MPD:59937   regression_HD   residual score from regression of head dip count on horizontal activity in head dip task to assess novelty seeking, 10 min test   [score]
Data set, strains Kliethermes1   inbred   14 strains     sex: both     age: 8wks
Procedure hole board test
Ontology mappings

  STRAIN COMPARISON PLOT
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Kliethermes1 - residual score from regression of head dip count on horizontal activity in head dip task to assess novelty seeking, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means4.70   score -0.880   score
Median of the strain means-3.72   score -2.25   score
SD of the strain means± 29.3 ± 18.3
Coefficient of variation (CV)6.24 -20.9
Min–max range of strain means-26.3   –   81.4   score -30.0   –   45.0   score
Mean sample size per strain6.3   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1667.1927 1667.1927 5.2907 0.0227
strain 13 90053.6987 6927.2076 21.9828 < 0.0001
sex:strain 13 8145.0911 626.5455 1.9883 0.0249
Residuals 158 49788.9158 315.1197


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f -14.0 11.9   6 4.84 -0.846 -27.4, 4.4 -0.64
129S1/SvImJ m -9.26 10.8   6 4.41 -1.17 -22.0, 4.82 -0.46
A/J f -17.5 2.8   6 1.14 -0.16 -19.9, -12.0 -0.76
A/J m -5.92 11.7   6 4.8 -1.98 -17.5, 15.0 -0.27
AKR/J f 18.2 16.3   6 6.66 0.895 -12.7, 34.5 0.46
AKR/J m 7.58 13.2   5 5.9 1.74 -7.67, 24.4 0.46
BALB/cByJ f -16.7 19.3   5 8.61 -1.16 -39.0, 11.3 -0.73
BALB/cByJ m -17.5 11.2   6 4.56 -0.638 -34.0, 0.115 -0.91
BTBR T+ Itpr3tf/J f -25.2 10.2   6 4.15 -0.403 -40.1, -10.9 -1.02
BTBR T+ Itpr3tf/J m -30.0 8.96   6 3.66 -0.299 -36.7, -13.4 -1.59
C3H/HeJ f 1.64 4.69   6 1.91 2.86 -3.27, 7.74 -0.1
C3H/HeJ m 1.48 11.2   6 4.58 7.61 -12.6, 13.7 0.13
C57BL/6J f -26.3 23.1   12 6.68 -0.88 -49.8, 21.4 -1.06
C57BL/6J m -22.1 22.6   12 6.53 -1.02 -45.5, 19.8 -1.16
C57L/J f -9.07 15.7   6 6.43 -1.74 -31.7, 14.4 -0.47
C57L/J m 9.58 30.8   6 12.6 3.22 -35.7, 44.7 0.57
DBA/2J f 10.4 16.2   12 4.67 1.56 -4.46, 56.1 0.19
DBA/2J m -3.33 13.2   12 3.8 -3.95 -22.2, 12.5 -0.13
FVB/NJ f 11.7 22.8   5 10.2 1.94 -15.0, 47.5 0.24
FVB/NJ m -1.16 15.0   5 6.7 -12.9 -27.4, 9.07 -0.02
NOD/ShiLtJ f 35.9 31.1   6 12.7 0.866 -17.0, 74.5 1.06
NOD/ShiLtJ m 13.6 14.3   6 5.83 1.05 -6.41, 35.4 0.79
NZB/BlNJ f -10.9 18.3   6 7.49 -1.68 -34.7, 21.5 -0.53
NZB/BlNJ m -10.1 8.86   6 3.62 -0.875 -19.0, 5.0 -0.5
PERA/EiJ f 26.2 13.1   5 5.84 0.498 10.3, 42.2 0.73
PERA/EiJ m 9.81 10.9   6 4.47 1.12 -5.74, 25.8 0.58
PL/J f 81.4 28.2   6 11.5 0.346 56.3, 132.0 2.62
PL/J m 45.0 29.7   5 13.3 0.662 -7.47, 62.2 2.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f -14.022 7.2471 0.2916 -28.3356
129S1/SvImJ m -9.2632 7.2471 5.0505 -23.5768
A/J f -17.4733 7.2471 -3.1597 -31.787
A/J m -5.9216 7.2471 8.392 -20.2352
AKR/J f 18.2317 7.2471 32.5453 3.918
AKR/J m 7.581 7.9388 23.2608 -8.0988
BALB/cByJ f -16.6702 7.9388 -0.9904 -32.35
BALB/cByJ m -17.5074 7.2471 -3.1938 -31.8211
BTBR T+ Itpr3tf/J f -25.175 7.2471 -10.8614 -39.4886
BTBR T+ Itpr3tf/J m -29.9733 7.2471 -15.6597 -44.287
C3H/HeJ f 1.6422 7.2471 15.9558 -12.6715
C3H/HeJ m 1.4752 7.2471 15.7888 -12.8385
C57BL/6J f -26.297 5.1244 -16.1757 -36.4183
C57BL/6J m -22.1479 5.1244 -12.0266 -32.2692
C57L/J f -9.068 7.2471 5.2456 -23.3816
C57L/J m 9.5832 7.2471 23.8968 -4.7305
DBA/2J f 10.3787 5.1244 20.4999 0.2574
DBA/2J m -3.3322 5.1244 6.789 -13.4535
FVB/NJ f 11.733 7.9388 27.4128 -3.9468
FVB/NJ m -1.1583 7.9388 14.5215 -16.838
NOD/ShiLtJ f 35.8967 7.2471 50.2103 21.583
NOD/ShiLtJ m 13.6457 7.2471 27.9593 -0.668
NZB/BlNJ f -10.9198 7.2471 3.3938 -25.2335
NZB/BlNJ m -10.1178 7.2471 4.1958 -24.4315
PERA/EiJ f 26.22 7.9388 41.8998 10.5402
PERA/EiJ m 9.8108 7.2471 24.1245 -4.5028
PL/J f 81.39 7.2471 95.7036 67.0764
PL/J m 44.9606 7.9388 60.6404 29.2808


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both -11.6426 5.1244 -1.5213 -21.7638
A/J both -11.6975 5.1244 -1.5762 -21.8187
AKR/J both 12.9063 5.3746 23.5216 2.2911
BALB/cByJ both -17.0888 5.3746 -6.4736 -27.7041
BTBR T+ Itpr3tf/J both -27.5742 5.1244 -17.4529 -37.6954
C3H/HeJ both 1.5587 5.1244 11.6799 -8.5626
C57BL/6J both -24.2225 3.6235 -17.0656 -31.3793
C57L/J both 0.2576 5.1244 10.3788 -9.8637
DBA/2J both 3.5232 3.6235 10.68 -3.6336
FVB/NJ both 5.2874 5.6136 16.3747 -5.7999
NOD/ShiLtJ both 24.7712 5.1244 34.8924 14.6499
NZB/BlNJ both -10.5188 5.1244 -0.3976 -20.6401
PERA/EiJ both 18.0154 5.3746 28.6307 7.4002
PL/J both 63.1753 5.3746 73.7906 52.56




  GWAS USING LINEAR MIXED MODELS