Phenotype measure:   Kliethermes1   regression_time_NP

ID, description, units MPD:59919   regression_time_NP   residual score from regression of time spent in novel compartment on total activity in novelty preference apparatus, 20 min test   [score]
Data set, strains Kliethermes1   inbred   14 strains     sex: both     age: 8wks
Procedure two chamber assay
Ontology mappings

  STRAIN COMPARISON PLOT
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Kliethermes1 - residual score from regression of time spent in novel compartment on total activity in novelty preference apparatus, 20 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means-27.7   score 24.6   score
Median of the strain means29.3   score 30.9   score
SD of the strain means± 160 ± 111
Coefficient of variation (CV)-5.79 4.52
Min–max range of strain means-362   –   153   score -254   –   171   score
Mean sample size per strain6.3   mice 6.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 71982.8017 71982.8017 2.0348 0.1557
strain 13 2689144.0676 206857.236 5.8474 < 0.0001
sex:strain 13 465064.2332 35774.1718 1.0113 0.4431
Residuals 157 5554041.4919 35376.0605


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f -173.0 326.0   6 133.0 -1.88 -483.0, 247.0 -0.91
129S1/SvImJ m 29.6 226.0   6 92.2 7.64 -224.0, 314.0 0.04
A/J f -362.0 229.0   6 93.4 -0.631 -515.0, 42.3 -2.09
A/J m -254.0 427.0   6 174.0 -1.68 -552.0, 331.0 -2.51
AKR/J f 142.0 149.0   6 60.8 1.05 -39.0, 372.0 1.06
AKR/J m 171.0 93.5   6 38.2 0.547 22.6, 260.0 1.32
BALB/cByJ f -188.0 367.0   5 164.0 -1.95 -634.0, 125.0 -1.0
BALB/cByJ m 89.9 354.0   6 144.0 3.93 -580.0, 375.0 0.59
BTBR T+ Itpr3tf/J f 52.3 98.9   6 40.4 1.89 -80.3, 183.0 0.5
BTBR T+ Itpr3tf/J m 14.7 166.0   6 67.8 11.3 -281.0, 150.0 -0.09
C3H/HeJ f 112.0 22.8   6 9.31 0.204 95.1, 157.0 0.87
C3H/HeJ m 167.0 42.5   6 17.3 0.254 122.0, 214.0 1.28
C57BL/6J f -97.1 97.5   11 29.4 -1.0 -155.0, 165.0 -0.43
C57BL/6J m -45.8 104.0   12 30.1 -2.28 -207.0, 102.0 -0.63
C57L/J f -126.0 177.0   6 72.4 -1.41 -280.0, 198.0 -0.61
C57L/J m -77.4 123.0   6 50.4 -1.6 -212.0, 143.0 -0.92
DBA/2J f 153.0 151.0   12 43.6 0.988 -74.9, 410.0 1.13
DBA/2J m 43.7 144.0   9 48.0 3.3 -209.0, 216.0 0.17
FVB/NJ f 6.28 134.0   6 54.8 21.4 -203.0, 145.0 0.21
FVB/NJ m 32.1 49.3   6 20.1 1.53 -28.1, 95.4 0.07
NOD/ShiLtJ f -187.0 60.0   6 24.5 -0.321 -257.0, -87.3 -0.99
NOD/ShiLtJ m -58.3 90.0   6 36.8 -1.54 -156.0, 63.8 -0.75
NZB/BlNJ f 105.0 192.0   6 78.4 1.83 -168.0, 260.0 0.83
NZB/BlNJ m 120.0 112.0   6 45.9 0.939 -54.0, 278.0 0.86
PERA/EiJ f 121.0 77.3   5 34.6 0.637 28.8, 190.0 0.93
PERA/EiJ m 15.6 389.0   6 159.0 25.0 -476.0, 429.0 -0.08
PL/J f 54.0 65.5   6 26.7 1.21 -34.7, 128.0 0.51
PL/J m 96.6 37.0   5 16.5 0.383 57.0, 135.0 0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f -173.2667 76.7855 -21.6008 -324.9325
129S1/SvImJ m 29.56 76.7855 181.2258 -122.1058
A/J f -362.1833 76.7855 -210.5175 -513.8492
A/J m -254.0167 76.7855 -102.3508 -405.6825
AKR/J f 142.2723 76.7855 293.9382 -9.3935
AKR/J m 170.9733 76.7855 322.6392 19.3075
BALB/cByJ f -187.54 84.1143 -21.3984 -353.6816
BALB/cByJ m 89.9067 76.7855 241.5725 -61.7592
BTBR T+ Itpr3tf/J f 52.2725 76.7855 203.9383 -99.3933
BTBR T+ Itpr3tf/J m 14.6833 76.7855 166.3492 -136.9825
C3H/HeJ f 112.0267 76.7855 263.6925 -39.6392
C3H/HeJ m 167.0167 76.7855 318.6825 15.3508
C57BL/6J f -97.1432 56.7098 14.8695 -209.1558
C57BL/6J m -45.8346 54.2955 61.4094 -153.0785
C57L/J f -125.57 76.7855 26.0958 -277.2358
C57L/J m -77.3633 76.7855 74.3025 -229.0292
DBA/2J f 152.9092 54.2955 260.1531 45.6652
DBA/2J m 43.6778 62.6951 167.5124 -80.1569
FVB/NJ f 6.28 76.7855 157.9458 -145.3858
FVB/NJ m 32.1117 76.7855 183.7775 -119.5542
NOD/ShiLtJ f -187.1617 76.7855 -35.4958 -338.8275
NOD/ShiLtJ m -58.3483 76.7855 93.3175 -210.0142
NZB/BlNJ f 104.6333 76.7855 256.2992 -47.0325
NZB/BlNJ m 119.635 76.7855 271.3008 -32.0308
PERA/EiJ f 121.322 84.1143 287.4636 -44.8196
PERA/EiJ m 15.5667 76.7855 167.2325 -136.0992
PL/J f 54.0167 76.7855 205.6825 -97.6492
PL/J m 96.58 84.1143 262.7216 -69.5616


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both -71.8533 54.2955 35.3906 -179.0973
A/J both -308.1 54.2955 -200.856 -415.344
AKR/J both 156.6228 54.2955 263.8668 49.3789
BALB/cByJ both -48.8167 56.9456 63.6617 -161.2951
BTBR T+ Itpr3tf/J both 33.4779 54.2955 140.7219 -73.766
C3H/HeJ both 139.5217 54.2955 246.7656 32.2777
C57BL/6J both -71.4889 39.2556 6.0484 -149.0261
C57L/J both -101.4667 54.2955 5.7773 -208.7106
DBA/2J both 98.2935 41.4689 180.2024 16.3846
FVB/NJ both 19.1958 54.2955 126.4398 -88.0481
NOD/ShiLtJ both -122.755 54.2955 -15.511 -229.999
NZB/BlNJ both 112.1342 54.2955 219.3781 4.8902
PERA/EiJ both 68.4443 56.9456 180.9227 -44.0341
PL/J both 75.2983 56.9456 187.7767 -37.1801




  GWAS USING LINEAR MIXED MODELS