Project measure / variable:   Schughart3   status_day_survivalA

ID, description, units MPD:57191   status_day_survivalA   susceptibility to viral infection (0=resistant, 1=susceptible), mortality rate   [score]  10 FFU group  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
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  STRAIN COMPARISON PLOT
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Schughart3 - susceptibility to viral infection (0=resistant, 1=susceptible), mortality rate 10 FFU group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.641   score 0.522   score
Median of the strain means0.762   score 0.522   score
SD of the strain means± 0.426 ± 0.444
Coefficient of variation (CV)0.665 0.851
Min–max range of strain means0   –   1.00   score 0   –   1.00   score
Mean sample size per strain10.5   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8503 0.8503 9.9679 0.0019
strain 7 25.9284 3.7041 43.424 < 0.0001
sex:strain 7 1.324 0.1891 2.2174 0.0358
Residuals 150 12.7949 0.0853


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.889 0.333   9 0.111 0.375 0.58
129S1/SvImJ m 0.545 0.522   11 0.157 0.957 0.05
A/J f 1.0 0.0   10 0.0 0.0 1.0, 1.0 0.84
A/J m 1.0 0.0   10 0.0 0.0 1.0, 1.0 1.07
C57BL/6J f 0.636 0.505   11 0.152 0.793 -0.01
C57BL/6J m 0.5 0.527   10 0.167 1.05 -0.05
CAST/EiJ f 1.0 0.0   10 0.0 0.0 1.0, 1.0 0.84
CAST/EiJ m 1.0 0.0   7 0.0 0.0 1.0, 1.0 1.07
NOD/ShiLtJ f 0.6 0.516   10 0.163 0.861 -0.1
NOD/ShiLtJ m 0.133 0.352   15 0.0909 2.64 -0.88
NZO/HlLtJ f 0.0 0.0   10 0.0 0.0 -1.5
NZO/HlLtJ m 0.0 0.0   9 0.0 0.0 -1.18
PWK/PhJ f 0.0 0.0   12 0.0 0.0 -1.5
PWK/PhJ m 0.0 0.0   10 0.0 0.0 -1.18
WSB/EiJ f 1.0 0.0   12 0.0 0.0 1.0, 1.0 0.84
WSB/EiJ m 1.0 0.0   10 0.0 0.0 1.0, 1.0 1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.8889 0.0974 1.0813 0.6965
129S1/SvImJ m 0.5455 0.0881 0.7195 0.3715
A/J f 1.0 0.0924 1.1825 0.8175
A/J m 1.0 0.0924 1.1825 0.8175
C57BL/6J f 0.6364 0.0881 0.8104 0.4624
C57BL/6J m 0.5 0.0924 0.6825 0.3175
CAST/EiJ f 1.0 0.0924 1.1825 0.8175
CAST/EiJ m 1.0 0.1104 1.2181 0.7819
NOD/ShiLtJ f 0.6 0.0924 0.7825 0.4175
NOD/ShiLtJ m 0.1333 0.0754 0.2823 -0.0157
NZO/HlLtJ f 0.0 0.0924 0.1825 -0.1825
NZO/HlLtJ m 0.0 0.0974 0.1924 -0.1924
PWK/PhJ f 0.0 0.0843 0.1666 -0.1666
PWK/PhJ m 0.0 0.0924 0.1825 -0.1825
WSB/EiJ f 1.0 0.0843 1.1666 0.8334
WSB/EiJ m 1.0 0.0924 1.1825 0.8175


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.7172 0.0656 0.8469 0.5875
A/J both 1.0 0.0653 1.129 0.871
C57BL/6J both 0.5682 0.0638 0.6943 0.4421
CAST/EiJ both 1.0 0.072 1.1422 0.8578
NOD/ShiLtJ both 0.3667 0.0596 0.4845 0.2489
NZO/HlLtJ both 0.0 0.0671 0.1326 -0.1326
PWK/PhJ both 0.0 0.0625 0.1235 -0.1235
WSB/EiJ both 1.0 0.0625 1.1235 0.8765




  GWAS USING LINEAR MIXED MODELS