Phenotype measure:   Schughart3   pctbwB_d6

ID, description, units MPD:57136   pctbwB_d6   body weight as percent of baseline, 2000 FFU group   [%]  post-infection day 6   measure
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   6 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 2000 FFU group post-infection day 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains6 strains
Mean of the strain means81.4   % 79.8   %
Median of the strain means74.2   % 75.0   %
SD of the strain means± 10.8 ± 9.96
Coefficient of variation (CV)0.133 0.125
Min–max range of strain means72.5   –   94.8   % 71.8   –   92.8   %
Mean sample size per strain7.4   mice 7.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 34.1035 34.1035 1.7696 0.1877
strain 4 7166.9768 1791.7442 92.9712 < 0.0001
sex:strain 4 32.0635 8.0159 0.4159 0.7966
Residuals 71 1368.3139 19.272


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 74.2 5.06   7 1.91 0.0682 71.1, 85.5 -0.67
129S1/SvImJ m 75.6 4.56   10 1.44 0.0604 70.8, 87.3 -0.42
C57BL/6J f 72.5 0.636   2   0.45 0.00878 72.0, 73.0 -0.82
C57BL/6J m 71.9 1.58   8 0.56 0.022 70.1, 74.5 -0.79
NOD/ShiLtJ f 74.0 2.6   8 0.919 0.0351 71.3, 79.4 -0.68
NOD/ShiLtJ m 74.4 2.23   5 0.997 0.0299 71.8, 77.8 -0.54
NZO/HlLtJ f 94.8 3.19   9 1.06 0.0336 87.7, 98.1 1.24
NZO/HlLtJ m 92.8 7.44   11 2.24 0.0801 71.4, 97.5 1.31
PWK/PhJ f 91.4 4.14   11 1.25 0.0454 85.0, 97.9 0.93
PWK/PhJ m 92.2 3.89   10 1.23 0.0422 88.3, 99.4 1.25
WSB/EiJ m 71.8 0.0   1   0.0 0.0 71.8, 71.8 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 74.1614 1.6593 77.4699 70.853
129S1/SvImJ m 75.579 1.3882 78.3471 72.8109
C57BL/6J f 72.5 3.1042 78.6896 66.3104
C57BL/6J m 71.91 1.5521 75.0048 68.8152
NOD/ShiLtJ f 73.9875 1.5521 77.0823 70.8927
NOD/ShiLtJ m 74.406 1.9633 78.3206 70.4914
NZO/HlLtJ f 94.8078 1.4633 97.7256 91.89
NZO/HlLtJ m 92.8382 1.3236 95.4774 90.1989
PWK/PhJ f 91.3555 1.3236 93.9947 88.7162
PWK/PhJ m 92.175 1.3882 94.9431 89.4069


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 74.8702 1.0817 77.0271 72.7134
C57BL/6J both 72.205 1.7353 75.6651 68.7449
NOD/ShiLtJ both 74.1967 1.2513 76.6919 71.7016
NZO/HlLtJ both 93.823 0.9866 95.7902 91.8558
PWK/PhJ both 91.7652 0.9591 93.6775 89.8529




GWAS analysis not available: At least 12 strains are required