Project measure / variable:   Schughart3   pctbwA_d14

ID, description, units MPD:57124   pctbwA_d14   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 14  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   5 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 14



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains5 strains
Mean of the strain means87.8   % 91.8   %
Median of the strain means89.5   % 93.9   %
SD of the strain means± 9.77 ± 5.41
Coefficient of variation (CV)0.111 0.0589
Min–max range of strain means74.8   –   97.8   % 83.4   –   96.5   %
Mean sample size per strain6.2   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.6217 0.6217 0.0141 0.9058
strain 3 1010.0068 336.6689 7.6454 0.0002
sex:strain 3 600.4212 200.1404 4.545 0.0062
Residuals 59 2598.1013 44.0356


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 74.8 0.0   1   0.0 0.0 74.8, 74.8 -1.33
129S1/SvImJ m 89.6 9.57   5 4.28 0.107 80.4, 103.0 -0.41
C57BL/6J f 89.5 6.73   4 3.37 0.0752 82.3, 96.2 0.18
C57BL/6J m 83.4 8.77   5 3.92 0.105 74.3, 94.9 -1.56
NOD/ShiLtJ f 81.0 9.55   4 4.77 0.118 71.9, 94.3 -0.69
NOD/ShiLtJ m 93.9 8.71   13 2.42 0.0928 73.7, 110.0 0.38
NZO/HlLtJ f 95.8 5.58   10 1.76 0.0582 84.7, 104.0 0.82
NZO/HlLtJ m 96.5 5.24   9 1.75 0.0543 88.8, 104.0 0.86
PWK/PhJ f 97.8 4.59   12 1.33 0.047 90.9, 109.0 1.03
PWK/PhJ m 95.7 5.14   10 1.63 0.0538 89.8, 104.0 0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C57BL/6J f 89.5175 3.318 96.1567 82.8783
C57BL/6J m 83.374 2.9677 89.3123 77.4357
NOD/ShiLtJ f 80.9625 3.318 87.6017 74.3233
NOD/ShiLtJ m 93.8692 1.8405 97.552 90.1864
NZO/HlLtJ f 95.791 2.0985 99.99 91.592
NZO/HlLtJ m 96.5456 2.212 100.9717 92.1194
PWK/PhJ f 97.8108 1.9156 101.644 93.9777
PWK/PhJ m 95.681 2.0985 99.88 91.482


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
C57BL/6J both 86.4458 2.2258 90.8995 81.992
NOD/ShiLtJ both 87.4159 1.8971 91.212 83.6197
NZO/HlLtJ both 96.1683 1.5245 99.2188 93.1178
PWK/PhJ both 96.7459 1.4207 99.5887 93.9032




  GWAS USING LINEAR MIXED MODELS