Project measure / variable:   Schughart3   pctbwA_d12

ID, description, units MPD:57122   pctbwA_d12   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 12  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   5 strains     sex: both     age: 7-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 12



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains5 strains
Mean of the strain means84.6   % 89.1   %
Median of the strain means81.5   % 88.9   %
SD of the strain means± 10.9 ± 6.78
Coefficient of variation (CV)0.129 0.0761
Min–max range of strain means72.4   –   97.3   % 79.7   –   95.9   %
Mean sample size per strain6.6   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.3473 7.3473 0.1616 0.689
strain 4 3308.3182 827.0795 18.1886 < 0.0001
sex:strain 4 645.1592 161.2898 3.547 0.0111
Residuals 65 2955.7053 45.4724


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 72.4 1.64   3 0.946 0.0226 70.7, 74.0 -1.11
129S1/SvImJ m 85.8 10.4   5 4.65 0.121 75.3, 101.0 -0.49
C57BL/6J f 81.5 8.38   4 4.19 0.103 73.6, 89.0 -0.28
C57BL/6J m 79.7 7.9   5 3.53 0.0991 72.5, 91.8 -1.39
NOD/ShiLtJ f 77.0 4.71   4 2.36 0.0612 71.7, 83.2 -0.69
NOD/ShiLtJ m 88.9 9.44   13 2.62 0.106 73.4, 107.0 -0.03
NZO/HlLtJ f 94.6 4.51   10 1.43 0.0477 85.6, 101.0 0.92
NZO/HlLtJ m 95.9 4.72   9 1.57 0.0492 89.2, 104.0 1.0
PWK/PhJ f 97.3 4.9   12 1.41 0.0503 91.9, 108.0 1.17
PWK/PhJ m 95.3 5.74   10 1.81 0.0602 88.2, 104.0 0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 72.4267 3.8933 80.202 64.6513
129S1/SvImJ m 85.8 3.0157 91.8228 79.7772
C57BL/6J f 81.5225 3.3717 88.2562 74.7888
C57BL/6J m 79.728 3.0157 85.7508 73.7052
NOD/ShiLtJ f 76.975 3.3717 83.7087 70.2413
NOD/ShiLtJ m 88.9 1.8703 92.6352 85.1648
NZO/HlLtJ f 94.62 2.1324 98.8787 90.3613
NZO/HlLtJ m 95.9344 2.2478 100.4236 91.4453
PWK/PhJ f 97.2517 1.9466 101.1394 93.364
PWK/PhJ m 95.272 2.1324 99.5307 91.0133


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 79.1133 2.4623 84.0309 74.1958
C57BL/6J both 80.6252 2.2618 85.1423 76.1082
NOD/ShiLtJ both 82.9375 1.9278 86.7876 79.0874
NZO/HlLtJ both 95.2772 1.5492 98.3711 92.1833
PWK/PhJ both 96.2618 1.4437 99.145 93.3786




  GWAS USING LINEAR MIXED MODELS