Project measure / variable:   Schughart3   pctbwA_d10

ID, description, units MPD:57120   pctbwA_d10   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 10  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   6 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 10



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains6 strains
Mean of the strain means82.6   % 84.3   %
Median of the strain means75.0   % 81.2   %
SD of the strain means± 11.7 ± 9.41
Coefficient of variation (CV)0.141 0.112
Min–max range of strain means72.7   –   96.8   % 74.3   –   96.0   %
Mean sample size per strain7.0   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.307 3.307 0.0809 0.7769
strain 4 6236.2521 1559.063 38.1367 < 0.0001
sex:strain 4 203.708 50.927 1.2457 0.2998
Residuals 69 2820.7846 40.8809


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 72.7 2.98   4 1.49 0.0411 70.1, 76.3 -0.85
129S1/SvImJ m 81.2 9.74   6 3.98 0.12 73.0, 97.7 -0.33
C57BL/6J f 75.0 2.66   4 1.33 0.0355 71.4, 77.1 -0.65
C57BL/6J m 77.1 4.26   5 1.91 0.0553 72.2, 82.8 -0.76
NOD/ShiLtJ f 74.6 2.47   5 1.1 0.0331 70.6, 77.0 -0.68
NOD/ShiLtJ m 81.2 10.7   14 2.86 0.132 71.5, 105.0 -0.33
NZO/HlLtJ f 93.7 4.52   10 1.43 0.0482 86.8, 99.8 0.95
NZO/HlLtJ m 95.9 3.6   9 1.2 0.0375 90.5, 101.0 1.23
PWK/PhJ f 96.8 4.38   12 1.26 0.0452 92.0, 106.0 1.22
PWK/PhJ m 96.0 4.87   10 1.54 0.0508 89.7, 103.0 1.25
WSB/EiJ m 74.3 0.0636   2   0.045 0.000857 74.2, 74.3 -1.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 72.705 3.1969 79.0827 66.3273
129S1/SvImJ m 81.1867 2.6103 86.394 75.9793
C57BL/6J f 74.965 3.1969 81.3427 68.5873
C57BL/6J m 77.054 2.8594 82.7584 71.3496
NOD/ShiLtJ f 74.632 2.8594 80.3364 68.9276
NOD/ShiLtJ m 81.1936 1.7088 84.6026 77.7846
NZO/HlLtJ f 93.732 2.0219 97.7656 89.6984
NZO/HlLtJ m 95.9189 2.1313 100.1707 91.6671
PWK/PhJ f 96.7792 1.8457 100.4613 93.097
PWK/PhJ m 95.952 2.0219 99.9856 91.9184


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 76.9458 2.0636 81.0626 72.8291
C57BL/6J both 76.0095 2.1446 80.2878 71.7312
NOD/ShiLtJ both 77.9128 1.6656 81.2355 74.5901
NZO/HlLtJ both 94.8254 1.4689 97.7558 91.8951
PWK/PhJ both 96.3656 1.3688 99.0963 93.6348




  GWAS USING LINEAR MIXED MODELS