Project measure / variable:   Schughart3   pctbwA_d6

ID, description, units MPD:57116   pctbwA_d6   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 6  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means82.5   % 87.0   %
Median of the strain means81.8   % 89.5   %
SD of the strain means± 8.04 ± 7.48
Coefficient of variation (CV)0.0975 0.0860
Min–max range of strain means73.4   –   94.9   % 75.4   –   96.3   %
Mean sample size per strain10.1   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 820.6582 820.6582 26.5803 < 0.0001
strain 7 7840.1246 1120.0178 36.2763 < 0.0001
sex:strain 7 395.4141 56.4877 1.8296 0.0857
Residuals 147 4538.5732 30.8746


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 82.3 6.09   9 2.03 0.074 75.7, 92.6 -0.02
129S1/SvImJ m 90.6 6.84   11 2.06 0.0755 80.9, 101.0 0.48
A/J f 73.4 1.88   8 0.663 0.0256 70.7, 75.8 -1.13
A/J m 75.4 2.74   10 0.865 0.0363 72.0, 81.2 -1.55
C57BL/6J f 81.6 8.29   11 2.5 0.102 71.9, 95.7 -0.11
C57BL/6J m 88.8 9.31   10 2.95 0.105 76.4, 100.0 0.24
CAST/EiJ f 75.1 1.69   9 0.563 0.0225 72.3, 78.0 -0.92
CAST/EiJ m 77.9 4.55   7 1.72 0.0583 71.6, 84.0 -1.21
NOD/ShiLtJ f 82.0 5.26   10 1.66 0.0642 73.9, 89.8 -0.06
NOD/ShiLtJ m 90.2 6.88   15 1.78 0.0763 83.5, 103.0 0.43
NZO/HlLtJ f 94.9 3.73   10 1.18 0.0393 87.4, 99.5 1.54
NZO/HlLtJ m 96.3 3.99   9 1.33 0.0414 91.2, 102.0 1.25
PWK/PhJ f 93.8 3.04   12 0.877 0.0324 89.4, 98.3 1.41
PWK/PhJ m 93.7 6.15   10 1.94 0.0656 86.8, 107.0 0.9
WSB/EiJ f 76.8 3.41   12 0.986 0.0445 71.1, 82.2 -0.71
WSB/EiJ m 82.9 6.08   10 1.92 0.0733 75.9, 90.9 -0.54


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 82.3411 1.8522 86.0014 78.6808
129S1/SvImJ m 90.5782 1.6753 93.8891 87.2673
A/J f 73.3888 1.9645 77.2711 69.5064
A/J m 75.383 1.7571 78.8555 71.9105
C57BL/6J f 81.6173 1.6753 84.9281 78.3064
C57BL/6J m 88.768 1.7571 92.2405 85.2955
CAST/EiJ f 75.1444 1.8522 78.8048 71.4841
CAST/EiJ m 77.9443 2.1002 82.0947 73.7939
NOD/ShiLtJ f 82.035 1.7571 85.5075 78.5625
NOD/ShiLtJ m 90.152 1.4347 92.9873 87.3167
NZO/HlLtJ f 94.881 1.7571 98.3535 91.4085
NZO/HlLtJ m 96.2889 1.8522 99.9492 92.6286
PWK/PhJ f 93.7892 1.604 96.9591 90.6192
PWK/PhJ m 93.749 1.7571 97.2215 90.2765
WSB/EiJ f 76.7508 1.604 79.9208 73.5809
WSB/EiJ m 82.899 1.7571 86.3715 79.4265


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 86.4596 1.2487 88.9274 83.9919
A/J both 74.3859 1.3178 76.9902 71.7815
C57BL/6J both 85.1926 1.2139 87.5916 82.7937
CAST/EiJ both 76.5444 1.4001 79.3113 73.7774
NOD/ShiLtJ both 86.0935 1.1342 88.335 83.852
NZO/HlLtJ both 95.5849 1.2765 98.1076 93.0622
PWK/PhJ both 93.7691 1.1896 96.12 91.4182
WSB/EiJ both 79.8249 1.1896 82.1758 77.474




  GWAS USING LINEAR MIXED MODELS