Project measure / variable:   Schughart3   pctbwA_d2

ID, description, units MPD:57112   pctbwA_d2   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 2  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means96.2   % 97.4   %
Median of the strain means96.5   % 98.1   %
SD of the strain means± 3.28 ± 2.93
Coefficient of variation (CV)0.0341 0.0301
Min–max range of strain means90.8   –   100   % 91.0   –   100   %
Mean sample size per strain10.5   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 89.6739 89.6739 6.9121 0.0095
strain 7 1337.3876 191.0554 14.7266 < 0.0001
sex:strain 7 185.3618 26.4803 2.0411 0.0535
Residuals 150 1946.0285 12.9735


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 96.2 3.85   9 1.28 0.04 90.4, 102.0 0.02
129S1/SvImJ m 99.6 4.01   11 1.21 0.0402 92.2, 105.0 0.77
A/J f 98.1 2.77   10 0.875 0.0282 93.0, 104.0 0.6
A/J m 95.9 2.14   10 0.676 0.0223 93.6, 100.0 -0.49
C57BL/6J f 96.8 2.18   11 0.657 0.0225 93.7, 99.5 0.2
C57BL/6J m 98.9 2.29   10 0.723 0.0231 95.8, 103.0 0.53
CAST/EiJ f 93.9 4.37   10 1.38 0.0465 84.7, 97.9 -0.69
CAST/EiJ m 97.3 2.4   7 0.906 0.0247 94.4, 101.0 -0.02
NOD/ShiLtJ f 100.0 2.72   10 0.86 0.0271 96.1, 103.0 1.18
NOD/ShiLtJ m 100.0 3.48   15 0.9 0.0348 94.3, 108.0 0.9
NZO/HlLtJ f 100.0 4.55   10 1.44 0.0453 91.2, 105.0 1.18
NZO/HlLtJ m 99.1 3.21   9 1.07 0.0324 94.5, 104.0 0.6
PWK/PhJ f 90.8 4.3   12 1.24 0.0474 84.6, 101.0 -1.63
PWK/PhJ m 91.0 5.95   10 1.88 0.0653 82.2, 102.0 -2.17
WSB/EiJ f 93.4 4.18   12 1.21 0.0447 85.8, 98.9 -0.84
WSB/EiJ m 97.0 2.03   10 0.642 0.0209 92.7, 101.0 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 96.1978 1.2006 98.5701 93.8255
129S1/SvImJ m 99.6391 1.086 101.7849 97.4932
A/J f 98.136 1.139 100.3866 95.8854
A/J m 95.866 1.139 98.1166 93.6154
C57BL/6J f 96.8264 1.086 98.9722 94.6805
C57BL/6J m 98.892 1.139 101.1426 96.6414
CAST/EiJ f 93.942 1.139 96.1926 91.6914
CAST/EiJ m 97.27 1.3614 99.96 94.58
NOD/ShiLtJ f 100.32 1.139 102.5706 98.0694
NOD/ShiLtJ m 99.9933 0.93 101.8309 98.1557
NZO/HlLtJ f 100.36 1.139 102.6106 98.1094
NZO/HlLtJ m 99.1244 1.2006 101.4968 96.7521
PWK/PhJ f 90.7517 1.0398 92.8062 88.6972
PWK/PhJ m 91.01 1.139 93.2606 88.7594
WSB/EiJ f 93.3817 1.0398 95.4362 91.3272
WSB/EiJ m 96.988 1.139 99.2386 94.7374


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 97.9184 0.8095 99.5179 96.319
A/J both 97.001 0.8054 98.5924 95.4096
C57BL/6J both 97.8592 0.7869 99.414 96.3044
CAST/EiJ both 95.606 0.8875 97.3596 93.8524
NOD/ShiLtJ both 100.1567 0.7352 101.6094 98.7039
NZO/HlLtJ both 99.7422 0.8275 101.3772 98.1072
PWK/PhJ both 90.8808 0.7711 92.4045 89.3572
WSB/EiJ both 95.1848 0.7711 96.7085 93.6612




  GWAS USING LINEAR MIXED MODELS