Project measure / variable:   GMC20   IgM_17

ID, description, units MPD:56902   IgM_17   immunoglobulin M (plasma IgM)   [µg/mL]  at age 16-17wks  
Data set, strains GMC20   inbred w/CC8   7 strains     sex: both     age: 16-17wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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GMC20 - immunoglobulin M (plasma IgM) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means530   µg/mL 474   µg/mL
Median of the strain means470   µg/mL 508   µg/mL
SD of the strain means± 365 ± 298
Coefficient of variation (CV)0.688 0.628
Min–max range of strain means146   –   1054   µg/mL 165   –   989   µg/mL
Mean sample size per strain3.5   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12165.4464 12165.4464 0.2387 0.6287
strain 4 2947508.9549 736877.2387 14.4571 < 0.0001
sex:strain 4 449114.4205 112278.6051 2.2028 0.0926
Residuals 30 1529093.8639 50969.7955


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 359.0 76.4   4 38.2 0.213 284.0, 465.0 -0.47
129S1/SvImJ m 688.0 427.0   4 214.0 0.621 253.0, 1077.0 0.72
A/J f 196.0 79.4   4 39.7 0.405 100.0, 285.0 -0.92
A/J m 165.0 29.9   4 14.9 0.182 121.0, 185.0 -1.04
C57BL/6J f 581.0 290.0   4 145.0 0.499 294.0, 900.0 0.14
C57BL/6J m 508.0 313.0   4 157.0 0.616 178.0, 900.0 0.12
NOD/ShiLtJ f 846.0 159.0   4 79.3 0.188 725.0, 1077.0 0.87
NOD/ShiLtJ m 511.0 63.1   4 31.5 0.123 450.0, 599.0 0.13
NZO/HlLtJ f 1054.0 218.0   4 109.0 0.207 803.0, 1328.0 1.44
NZO/HlLtJ m 989.0 235.0   4 118.0 0.238 779.0, 1284.0 1.73
PWK/PhJ m 239.0 0.0   1   0.0 0.0 239.0, 239.0 -0.79
WSB/EiJ f 146.0 0.0   1   0.0 0.0 146.0, 146.0 -1.05
WSB/EiJ m 215.0 11.0   3 6.35 0.0512 203.0, 224.0 -0.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 358.7925 112.8825 589.3292 128.2558
129S1/SvImJ m 687.94 112.8825 918.4767 457.4033
A/J f 196.2225 112.8825 426.7592 -34.3142
A/J m 164.5425 112.8825 395.0792 -65.9942
C57BL/6J f 580.99 112.8825 811.5267 350.4533
C57BL/6J m 508.325 112.8825 738.8617 277.7883
NOD/ShiLtJ f 845.5525 112.8825 1076.0892 615.0158
NOD/ShiLtJ m 511.16 112.8825 741.6967 280.6233
NZO/HlLtJ f 1054.085 112.8825 1284.6217 823.5483
NZO/HlLtJ m 989.28 112.8825 1219.8167 758.7433


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 523.3662 79.82 686.3803 360.3522
A/J both 180.3825 79.82 343.3966 17.3684
C57BL/6J both 544.6575 79.82 707.6716 381.6434
NOD/ShiLtJ both 678.3563 79.82 841.3703 515.3422
NZO/HlLtJ both 1021.6825 79.82 1184.6966 858.6684




  GWAS USING LINEAR MIXED MODELS