Project measure / variable:   GMC18   LEANmass_wholebody

ID, description, units MPD:56733   LEANmass_wholebody   lean tissue mass, whole body including head   [g]  
Data set, strains GMC18   inbred w/CC8   7 strains     sex: both     age: 17-18wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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GMC18 - lean tissue mass, whole body including head



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means17.4   g 20.6   g
Median of the strain means17.1   g 19.9   g
SD of the strain means± 2.56 ± 3.93
Coefficient of variation (CV)0.147 0.191
Min–max range of strain means13.9   –   21.1   g 16.0   –   26.9   g
Mean sample size per strain13.8   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 761.739 761.739 130.6286 < 0.0001
strain 4 1310.8241 327.706 56.1974 < 0.0001
sex:strain 4 85.223 21.3057 3.6537 0.0072
Residuals 152 886.363 5.8313


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 18.1 2.0   16 0.501 0.111 14.6, 21.9 0.27
129S1/SvImJ m 19.9 1.83   16 0.458 0.092 17.1, 22.5 -0.17
A/J f 16.0 1.5   16 0.376 0.0943 13.5, 18.6 -0.55
A/J m 20.2 2.52   16 0.63 0.125 15.5, 25.4 -0.1
C57BL/6J f 19.1 1.95   16 0.488 0.102 15.9, 21.9 0.66
C57BL/6J m 24.9 2.15   16 0.537 0.0862 21.0, 28.8 1.1
CAST/EiJ m 16.0 1.15   4 0.577 0.0721 14.4, 17.0 -1.17
NOD/ShiLtJ f 21.1 2.31   18 0.545 0.109 16.6, 25.9 1.45
NOD/ShiLtJ m 26.9 2.69   16 0.672 0.0999 22.6, 32.4 1.61
NZO/HlLtJ f 13.9 1.76   16 0.44 0.127 10.6, 17.2 -1.37
NZO/HlLtJ m 18.3 4.28   16 1.07 0.234 13.1, 28.6 -0.58
WSB/EiJ f 16.2 0.0   1   0.0 0.0 16.2, 16.2 -0.47
WSB/EiJ m 17.9 0.768   3 0.443 0.0429 17.4, 18.8 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 18.0562 0.6037 19.2489 16.8635
129S1/SvImJ m 19.8966 0.6037 21.0894 18.7039
A/J f 15.9585 0.6037 17.1512 14.7658
A/J m 20.2127 0.6037 21.4054 19.02
C57BL/6J f 19.1149 0.6037 20.3077 17.9222
C57BL/6J m 24.9368 0.6037 26.1295 23.744
NOD/ShiLtJ f 21.1158 0.5692 22.2403 19.9913
NOD/ShiLtJ m 26.9127 0.6037 28.1054 25.72
NZO/HlLtJ f 13.8696 0.6037 15.0624 12.6769
NZO/HlLtJ m 18.2682 0.6037 19.4609 17.0755


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 18.9764 0.4269 19.8198 18.133
A/J both 18.0856 0.4269 18.929 17.2422
C57BL/6J both 22.0258 0.4269 22.8692 21.1825
NOD/ShiLtJ both 24.0142 0.4149 24.8339 23.1946
NZO/HlLtJ both 16.0689 0.4269 16.9123 15.2255




  GWAS USING LINEAR MIXED MODELS