Project measure / variable:   GMC16   TG_21

ID, description, units MPD:56549   TG_21   triglyceride (plasma TG)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
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  STRAIN COMPARISON PLOT
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GMC16 - triglyceride (plasma TG) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means1.65   mmol/L 2.40   mmol/L
Median of the strain means1.65   mmol/L 2.18   mmol/L
SD of the strain means± 0.513 ± 1.06
Coefficient of variation (CV)0.310 0.444
Min–max range of strain means0.867   –   2.26   mmol/L 1.00   –   4.53   mmol/L
Mean sample size per strain10.1   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 23.5633 23.5633 39.4538 < 0.0001
strain 7 95.3321 13.6189 22.8031 < 0.0001
sex:strain 7 17.5244 2.5035 4.1918 0.0003
Residuals 158 94.3635 0.5972


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.37 0.395   10 0.125 0.289 0.688, 1.92 -0.55
129S1/SvImJ m 1.88 0.476   12 0.137 0.254 1.1, 2.42 -0.48
A/J f 1.52 0.232   10 0.0734 0.153 1.22, 1.95 -0.26
A/J m 2.01 0.505   11 0.152 0.251 1.39, 2.99 -0.36
C57BL/6J f 1.16 0.111   10 0.035 0.0958 0.962, 1.33 -0.96
C57BL/6J m 1.73 0.437   12 0.126 0.252 0.683, 2.41 -0.62
CAST/EiJ f 2.03 0.639   12 0.185 0.315 0.67, 2.77 0.73
CAST/EiJ m 3.14 0.871   11 0.263 0.277 1.63, 4.39 0.7
NOD/ShiLtJ f 2.25 0.754   9 0.251 0.335 1.37, 3.59 1.16
NOD/ShiLtJ m 2.52 1.05   12 0.304 0.419 1.63, 5.44 0.12
NZO/HlLtJ f 2.26 0.474   10 0.15 0.21 1.51, 3.27 1.18
NZO/HlLtJ m 4.53 2.11   12 0.609 0.465 2.55, 8.7 2.01
PWK/PhJ f 1.77 0.287   10 0.0907 0.163 1.29, 2.24 0.23
PWK/PhJ m 2.35 0.591   11 0.178 0.251 1.15, 2.91 -0.04
WSB/EiJ f 0.867 0.312   10 0.0985 0.359 0.474, 1.55 -1.53
WSB/EiJ m 1.0 0.168   12 0.0485 0.168 0.762, 1.24 -1.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.3672 0.2444 1.8499 0.8845
129S1/SvImJ m 1.8757 0.2231 2.3163 1.435
A/J f 1.5207 0.2444 2.0034 1.038
A/J m 2.0098 0.233 2.47 1.5496
C57BL/6J f 1.1567 0.2444 1.6394 0.674
C57BL/6J m 1.7348 0.2231 2.1755 1.2942
CAST/EiJ f 2.0305 0.2231 2.4711 1.5899
CAST/EiJ m 3.1405 0.233 3.6008 2.6803
NOD/ShiLtJ f 2.2481 0.2576 2.7569 1.7393
NOD/ShiLtJ m 2.5169 0.2231 2.9575 2.0763
NZO/HlLtJ f 2.264 0.2444 2.7467 1.7813
NZO/HlLtJ m 4.531 0.2231 4.9716 4.0904
PWK/PhJ f 1.7657 0.2444 2.2484 1.283
PWK/PhJ m 2.3547 0.233 2.8149 1.8945
WSB/EiJ f 0.8668 0.2444 1.3495 0.3841
WSB/EiJ m 1.0014 0.2231 1.442 0.5608


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.6214 0.1654 1.9482 1.2947
A/J both 1.7653 0.1688 2.0987 1.4318
C57BL/6J both 1.4458 0.1654 1.7725 1.119
CAST/EiJ both 2.5855 0.1613 2.9041 2.267
NOD/ShiLtJ both 2.3825 0.1704 2.719 2.046
NZO/HlLtJ both 3.3975 0.1654 3.7243 3.0707
PWK/PhJ both 2.0602 0.1688 2.3937 1.7268
WSB/EiJ both 0.9341 0.1654 1.2609 0.6073




  GWAS USING LINEAR MIXED MODELS