Project measure / variable:   GMC16   urea_21

ID, description, units MPD:56545   urea_21   blood urea nitrogen (plasma BUN)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC16 - blood urea nitrogen (plasma BUN) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means10.5   mmol/L 11.5   mmol/L
Median of the strain means9.86   mmol/L 10.7   mmol/L
SD of the strain means± 2.17 ± 2.16
Coefficient of variation (CV)0.207 0.188
Min–max range of strain means8.04   –   13.6   mmol/L 9.19   –   15.5   mmol/L
Mean sample size per strain10.1   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 31.7373 31.7373 11.5034 0.0009
strain 7 686.0751 98.0107 35.5247 < 0.0001
sex:strain 7 35.1902 5.0272 1.8221 0.0865
Residuals 158 435.9131 2.7589


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.04 1.06   10 0.336 0.132 6.26, 9.42 -1.12
129S1/SvImJ m 9.55 2.05   12 0.592 0.215 7.06, 14.0 -0.88
A/J f 8.39 0.755   10 0.239 0.0901 7.13, 9.22 -0.96
A/J m 10.2 0.767   11 0.231 0.0754 8.96, 11.3 -0.58
C57BL/6J f 12.0 0.801   10 0.253 0.0665 11.1, 13.4 0.71
C57BL/6J m 12.9 1.47   12 0.426 0.114 10.3, 15.6 0.67
CAST/EiJ f 13.6 1.08   12 0.312 0.0793 11.8, 15.6 1.45
CAST/EiJ m 12.9 1.31   11 0.396 0.102 9.89, 14.7 0.67
NOD/ShiLtJ f 10.2 2.16   9 0.721 0.213 7.68, 13.6 -0.12
NOD/ShiLtJ m 11.2 2.38   12 0.687 0.212 8.67, 15.3 -0.12
NZO/HlLtJ f 8.86 0.669   10 0.211 0.0755 8.08, 9.92 -0.74
NZO/HlLtJ m 9.19 2.3   12 0.663 0.25 6.23, 13.3 -1.05
PWK/PhJ f 13.1 1.77   10 0.559 0.135 10.9, 15.7 1.22
PWK/PhJ m 15.5 2.95   11 0.888 0.19 9.31, 20.4 1.88
WSB/EiJ f 9.51 1.18   10 0.372 0.124 7.93, 11.5 -0.44
WSB/EiJ m 10.2 1.33   12 0.384 0.13 7.73, 12.1 -0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.035 0.5253 9.0724 6.9976
129S1/SvImJ m 9.5525 0.4795 10.4995 8.6055
A/J f 8.385 0.5253 9.4224 7.3476
A/J m 10.1818 0.5008 11.171 9.1927
C57BL/6J f 12.046 0.5253 13.0834 11.0086
C57BL/6J m 12.9033 0.4795 13.8504 11.9563
CAST/EiJ f 13.625 0.4795 14.572 12.678
CAST/EiJ m 12.8564 0.5008 13.8455 11.8672
NOD/ShiLtJ f 10.1578 0.5537 11.2513 9.0642
NOD/ShiLtJ m 11.2425 0.4795 12.1895 10.2955
NZO/HlLtJ f 8.856 0.5253 9.8934 7.8186
NZO/HlLtJ m 9.1867 0.4795 10.1337 8.2396
PWK/PhJ f 13.141 0.5253 14.1784 12.1036
PWK/PhJ m 15.4836 0.5008 16.4728 14.4945
WSB/EiJ f 9.509 0.5253 10.5464 8.4716
WSB/EiJ m 10.21 0.4795 11.157 9.263


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.7937 0.3556 9.4961 8.0914
A/J both 9.2834 0.3629 10.0001 8.5667
C57BL/6J both 12.4747 0.3556 13.177 11.7723
CAST/EiJ both 13.2407 0.3467 13.9254 12.556
NOD/ShiLtJ both 10.7001 0.3662 11.4235 9.9768
NZO/HlLtJ both 9.0213 0.3556 9.7237 8.319
PWK/PhJ both 14.3123 0.3629 15.029 13.5956
WSB/EiJ both 9.8595 0.3556 10.5618 9.1572




  GWAS USING LINEAR MIXED MODELS