Project measure / variable:   GMC16   lactate_17

ID, description, units MPD:56518   lactate_17   lactate (plasma)   [mmol/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
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  STRAIN COMPARISON PLOT
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GMC16 - lactate (plasma) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means9.24   mmol/L 9.14   mmol/L
Median of the strain means9.65   mmol/L 9.50   mmol/L
SD of the strain means± 2.86 ± 2.10
Coefficient of variation (CV)0.310 0.230
Min–max range of strain means5.54   –   13.1   mmol/L 5.48   –   11.5   mmol/L
Mean sample size per strain3.5   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0133 0.0133 0.0079 0.9299
strain 4 115.7722 28.943 17.1174 < 0.0001
sex:strain 4 16.1297 4.0324 2.3849 0.0734
Residuals 30 50.7256 1.6909


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.8 1.14   4 0.569 0.129 7.68, 10.4 -0.15
129S1/SvImJ m 9.5 1.51   4 0.756 0.159 8.25, 11.7 0.17
A/J f 10.5 2.54   4 1.27 0.243 8.59, 14.2 0.44
A/J m 11.5 1.22   4 0.608 0.106 9.99, 12.8 1.12
C57BL/6J f 11.0 0.042   4 0.021 0.00381 11.0, 11.1 0.61
C57BL/6J m 9.94 0.79   4 0.395 0.0796 9.25, 11.0 0.38
NOD/ShiLtJ f 13.1 1.15   4 0.576 0.088 11.9, 14.5 1.35
NOD/ShiLtJ m 11.3 1.15   4 0.577 0.102 9.93, 12.6 1.03
NZO/HlLtJ f 6.51 0.0858   4 0.0429 0.0132 6.39, 6.58 -0.95
NZO/HlLtJ m 7.9 1.45   4 0.723 0.183 5.84, 9.03 -0.59
PWK/PhJ m 8.36 0.0   1   0.0 0.0 8.36, 8.36 -0.37
WSB/EiJ f 5.54 0.0   1   0.0 0.0 5.54, 5.54 -1.29
WSB/EiJ m 5.48 0.126   3 0.0726 0.0229 5.35, 5.6 -1.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.8025 0.6502 10.1303 7.4747
129S1/SvImJ m 9.4975 0.6502 10.8253 8.1697
A/J f 10.47 0.6502 11.7978 9.1422
A/J m 11.505 0.6502 12.8328 10.1772
C57BL/6J f 11.025 0.6502 12.3528 9.6972
C57BL/6J m 9.935 0.6502 11.2628 8.6072
NOD/ShiLtJ f 13.1025 0.6502 14.4303 11.7747
NOD/ShiLtJ m 11.2575 0.6502 12.5853 9.9297
NZO/HlLtJ f 6.515 0.6502 7.8428 5.1872
NZO/HlLtJ m 7.9025 0.6502 9.2303 6.5747


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 9.15 0.4597 10.0889 8.2111
A/J both 10.9875 0.4597 11.9264 10.0486
C57BL/6J both 10.48 0.4597 11.4189 9.5411
NOD/ShiLtJ both 12.18 0.4597 13.1189 11.2411
NZO/HlLtJ both 7.2088 0.4597 8.1477 6.2698




  GWAS USING LINEAR MIXED MODELS