Project measure / variable:   GMC10   lean_13wk

ID, description, units MPD:55921   lean_13wk   lean tissue mass, whole body with head (NMR)   [g]  at age 12-13wks  
Data set, strains GMC10   inbred w/CC8   8 strains     sex: both     age: 12-13wks
Procedure NMR
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  STRAIN COMPARISON PLOT
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GMC10 - lean tissue mass, whole body with head (NMR) at age 12-13wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means12.4   g 15.7   g
Median of the strain means11.8   g 14.8   g
SD of the strain means± 4.40 ± 5.34
Coefficient of variation (CV)0.355 0.340
Min–max range of strain means8.62   –   22.0   g 10.5   –   26.2   g
Mean sample size per strain17.4   mice 15.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 530.802 530.802 532.9759 < 0.0001
strain 7 4731.7485 675.9641 678.7324 < 0.0001
sex:strain 7 104.9634 14.9948 15.0562 < 0.0001
Residuals 249 247.9844 0.9959


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 12.2 0.772   16 0.193 0.0635 10.8, 13.3 -0.05
129S1/SvImJ m 15.2 1.84   16 0.459 0.121 13.4, 19.1 -0.09
A/J f 11.5 0.834   16 0.208 0.0725 9.7, 13.3 -0.2
A/J m 14.3 0.648   16 0.162 0.0455 13.4, 15.5 -0.26
C57BL/6J f 12.6 0.71   16 0.177 0.0564 11.7, 14.0 0.05
C57BL/6J m 18.2 1.2   16 0.3 0.0659 16.6, 20.2 0.47
CAST/EiJ f 8.62 0.472   19 0.108 0.0548 7.7, 9.6 -0.86
CAST/EiJ m 10.5 0.753   16 0.188 0.0716 8.9, 11.7 -0.97
NOD/ShiLtJ f 14.4 0.716   18 0.169 0.0495 13.1, 15.9 0.45
NOD/ShiLtJ m 18.9 1.44   16 0.361 0.0765 16.9, 21.6 0.6
NZO/HlLtJ f 22.0 1.14   16 0.286 0.0519 20.2, 24.3 2.18
NZO/HlLtJ m 26.2 1.02   10 0.323 0.0389 24.0, 27.7 1.97
PWK/PhJ f 9.11 0.716   20 0.16 0.0786 7.7, 10.2 -0.75
PWK/PhJ m 11.3 0.887   20 0.198 0.0785 10.0, 12.6 -0.82
WSB/EiJ f 8.77 1.35   18 0.319 0.154 6.4, 11.7 -0.83
WSB/EiJ m 10.8 0.586   16 0.146 0.0543 9.5, 11.5 -0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 12.1563 0.2495 12.6476 11.6649
129S1/SvImJ m 15.1938 0.2495 15.6851 14.7024
A/J f 11.4938 0.2495 11.9851 11.0024
A/J m 14.2563 0.2495 14.7476 13.7649
C57BL/6J f 12.5875 0.2495 13.0789 12.0961
C57BL/6J m 18.2125 0.2495 18.7039 17.7211
CAST/EiJ f 8.6211 0.2289 9.072 8.1701
CAST/EiJ m 10.525 0.2495 11.0164 10.0336
NOD/ShiLtJ f 14.4444 0.2352 14.9077 13.9812
NOD/ShiLtJ m 18.9 0.2495 19.3914 18.4086
NZO/HlLtJ f 22.0 0.2495 22.4914 21.5086
NZO/HlLtJ m 26.21 0.3156 26.8316 25.5884
PWK/PhJ f 9.11 0.2232 9.5495 8.6705
PWK/PhJ m 11.295 0.2232 11.7345 10.8555
WSB/EiJ f 8.7667 0.2352 9.2299 8.3034
WSB/EiJ m 10.7938 0.2495 11.2851 10.3024


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 13.675 0.1764 14.0225 13.3275
A/J both 12.875 0.1764 13.2225 12.5275
C57BL/6J both 15.4 0.1764 15.7475 15.0525
CAST/EiJ both 9.573 0.1693 9.9065 9.2396
NOD/ShiLtJ both 16.6722 0.1714 17.0099 16.3346
NZO/HlLtJ both 24.105 0.2011 24.5012 23.7088
PWK/PhJ both 10.2025 0.1578 10.5133 9.8917
WSB/EiJ both 9.7802 0.1714 10.1179 9.4425




  GWAS USING LINEAR MIXED MODELS