Project measure / variable:   GMC06   NEFA

ID, description, units MPD:55524   NEFA   non-esterified fatty acids (plasma NEFA, 16h fast)   [mmol/L]  
Data set, strains GMC06   inbred   5 strains     sex: both     age: 10-11wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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GMC06 - non-esterified fatty acids (plasma NEFA, 16h fast)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains5 strains
Mean of the strain means1.10   mmol/L 1.20   mmol/L
Median of the strain means1.13   mmol/L 1.14   mmol/L
SD of the strain means± 0.118 ± 0.142
Coefficient of variation (CV)0.107 0.118
Min–max range of strain means0.949   –   1.23   mmol/L 1.07   –   1.42   mmol/L
Mean sample size per strain16.6   mice 16.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4026 0.4026 2.4452 0.1199
strain 4 1.9561 0.489 2.9701 0.0213
sex:strain 4 0.2528 0.0632 0.3838 0.82
Residuals 153 25.1919 0.1647


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.949 0.43   16 0.108 0.453 0.45, 1.84 -1.25
129S1/SvImJ m 1.11 0.292   16 0.073 0.264 0.58, 1.51 -0.63
A/J f 1.0 0.342   16 0.0855 0.341 0.59, 1.67 -0.81
A/J m 1.07 0.28   16 0.0699 0.261 0.73, 1.48 -0.92
C57BL/6J f 1.13 0.312   16 0.078 0.277 0.69, 1.71 0.29
C57BL/6J m 1.26 0.43   16 0.107 0.34 0.76, 2.2 0.42
NOD/ShiLtJ f 1.23 0.416   18 0.0981 0.338 0.7, 1.92 1.14
NOD/ShiLtJ m 1.42 0.358   16 0.0896 0.253 0.87, 1.9 1.55
NZO/HlLtJ f 1.17 0.696   17 0.169 0.593 0.46, 3.51 0.63
NZO/HlLtJ m 1.14 0.3   16 0.075 0.263 0.57, 1.63 -0.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.9494 0.1014 1.1498 0.749
129S1/SvImJ m 1.1075 0.1014 1.3079 0.9071
A/J f 1.0031 0.1014 1.2035 0.8027
A/J m 1.0713 0.1014 1.2717 0.8708
C57BL/6J f 1.1263 0.1014 1.3267 0.9258
C57BL/6J m 1.2644 0.1014 1.4648 1.064
NOD/ShiLtJ f 1.2317 0.0956 1.4206 1.0427
NOD/ShiLtJ m 1.4175 0.1014 1.6179 1.2171
NZO/HlLtJ f 1.1741 0.0984 1.3685 0.9797
NZO/HlLtJ m 1.1419 0.1014 1.3423 0.9415


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.0284 0.0717 1.1701 0.8867
A/J both 1.0372 0.0717 1.1789 0.8955
C57BL/6J both 1.1953 0.0717 1.337 1.0536
NOD/ShiLtJ both 1.3246 0.0697 1.4623 1.1869
NZO/HlLtJ both 1.158 0.0707 1.2976 1.0184




  GWAS USING LINEAR MIXED MODELS