Project measure / variable:   GMC06   nonHDL

ID, description, units MPD:55523   nonHDL   non-HDL cholesterol (plasma non-HDL) (CHOL minus HDL, 16h fast)   [mmol/L]  
Data set, strains GMC06   inbred   5 strains     sex: both     age: 10-11wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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GMC06 - non-HDL cholesterol (plasma non-HDL) (CHOL minus HDL, 16h fast)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains5 strains
Mean of the strain means0.814   mmol/L 1.10   mmol/L
Median of the strain means0.592   mmol/L 0.689   mmol/L
SD of the strain means± 0.528 ± 0.881
Coefficient of variation (CV)0.648 0.804
Min–max range of strain means0.373   –   1.72   mmol/L 0.489   –   2.64   mmol/L
Mean sample size per strain16.6   mice 16.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.1421 3.1421 35.5549 < 0.0001
strain 4 64.0263 16.0066 181.1222 < 0.0001
sex:strain 4 4.2825 1.0706 12.1146 < 0.0001
Residuals 153 13.5213 0.0884


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.798 0.256   16 0.0641 0.321 0.46, 1.1 -0.03
129S1/SvImJ m 0.992 0.298   16 0.0744 0.3 0.453, 1.44 -0.12
A/J f 0.373 0.146   16 0.0364 0.391 0.098, 0.551 -0.84
A/J m 0.489 0.168   16 0.0421 0.345 0.124, 0.685 -0.69
C57BL/6J f 0.592 0.167   16 0.0417 0.282 0.189, 0.778 -0.42
C57BL/6J m 0.673 0.185   16 0.0462 0.274 0.37, 0.926 -0.48
NOD/ShiLtJ f 0.589 0.156   18 0.0368 0.265 0.341, 0.83 -0.43
NOD/ShiLtJ m 0.689 0.204   16 0.051 0.296 0.321, 0.869 -0.46
NZO/HlLtJ f 1.72 0.372   17 0.0903 0.217 1.03, 2.14 1.71
NZO/HlLtJ m 2.64 0.647   16 0.162 0.245 1.28, 3.78 1.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.7984 0.0743 0.9452 0.6515
129S1/SvImJ m 0.9918 0.0743 1.1386 0.8449
A/J f 0.3727 0.0743 0.5196 0.2259
A/J m 0.4887 0.0743 0.6355 0.3419
C57BL/6J f 0.5916 0.0743 0.7384 0.4447
C57BL/6J m 0.6734 0.0743 0.8203 0.5266
NOD/ShiLtJ f 0.5889 0.0701 0.7274 0.4505
NOD/ShiLtJ m 0.6894 0.0743 0.8363 0.5426
NZO/HlLtJ f 1.7151 0.0721 1.8575 1.5726
NZO/HlLtJ m 2.6393 0.0743 2.7861 2.4925


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.8951 0.0526 0.9989 0.7912
A/J both 0.4307 0.0526 0.5345 0.3269
C57BL/6J both 0.6325 0.0526 0.7363 0.5287
NOD/ShiLtJ both 0.6392 0.0511 0.7401 0.5383
NZO/HlLtJ both 2.1772 0.0518 2.2795 2.0749




  GWAS USING LINEAR MIXED MODELS