Project measure / variable:   GMC04   LatFall_mean

ID, description, units MPD:55315   LatFall_mean   latency to fall from accelerating (8rpm/min) rotarod, mean of trials   [s]  
Data set, strains GMC04   inbred w/CC7   7 strains     sex: both     age: 9-10wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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GMC04 - latency to fall from accelerating (8rpm/min) rotarod, mean of trials



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means145   s 136   s
Median of the strain means152   s 127   s
SD of the strain means± 38.4 ± 36.3
Coefficient of variation (CV)0.264 0.267
Min–max range of strain means78.4   –   189   s 77.6   –   183   s
Mean sample size per strain17.4   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4906.4152 4906.4152 1.2286 0.2688
strain 6 275095.2066 45849.2011 11.4813 < 0.0001
sex:strain 6 14328.5467 2388.0911 0.598 0.7318
Residuals 228 910487.5876 3993.3666


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 112.0 38.4   16 9.6 0.343 76.0, 191.0 -0.87
129S1/SvImJ m 127.0 36.3   16 9.07 0.285 72.0, 219.0 -0.25
A/J f 78.4 15.1   16 3.77 0.192 58.0, 106.0 -1.74
A/J m 77.6 26.8   16 6.69 0.345 33.0, 126.0 -1.61
C57BL/6J f 174.0 53.6   16 13.4 0.308 63.0, 250.0 0.75
C57BL/6J m 175.0 46.6   16 11.6 0.266 55.0, 254.0 1.08
CAST/EiJ f 145.0 61.7   19 14.2 0.425 52.0, 245.0 -0.01
CAST/EiJ m 125.0 67.5   17 16.4 0.539 2.0, 248.0 -0.3
NOD/ShiLtJ f 167.0 79.6   18 18.8 0.477 18.0, 276.0 0.56
NOD/ShiLtJ m 148.0 103.0   16 25.8 0.699 16.0, 300.0 0.33
NZO/HlLtJ f 152.0 37.4   17 9.06 0.246 73.0, 211.0 0.17
NZO/HlLtJ m 116.0 53.8   17 13.0 0.465 15.0, 201.0 -0.55
PWK/PhJ f 189.0 80.0   20 17.9 0.423 34.0, 300.0 1.14
PWK/PhJ m 183.0 92.3   22 19.7 0.504 21.0, 293.0 1.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 111.875 15.7983 143.0043 80.7457
129S1/SvImJ m 127.4375 15.7983 158.5668 96.3082
A/J f 78.4375 15.7983 109.5668 47.3082
A/J m 77.625 15.7983 108.7543 46.4957
C57BL/6J f 174.0625 15.7983 205.1918 142.9332
C57BL/6J m 175.0625 15.7983 206.1918 143.9332
CAST/EiJ f 145.2632 14.4975 173.8293 116.697
CAST/EiJ m 125.3529 15.3266 155.5528 95.1531
NOD/ShiLtJ f 166.7778 14.8948 196.1267 137.4288
NOD/ShiLtJ m 147.9375 15.7983 179.0668 116.8082
NZO/HlLtJ f 151.7059 15.3266 181.9057 121.506
NZO/HlLtJ m 115.7059 15.3266 145.9057 85.506
PWK/PhJ f 189.1 14.1304 216.9429 161.2571
PWK/PhJ m 183.2273 13.4728 209.7744 156.6801


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 119.6562 11.1711 141.668 97.6445
A/J both 78.0312 11.1711 100.043 56.0195
C57BL/6J both 174.5625 11.1711 196.5742 152.5508
CAST/EiJ both 135.308 10.5485 156.093 114.5231
NOD/ShiLtJ both 157.3576 10.8563 178.7492 135.9661
NZO/HlLtJ both 133.7059 10.8375 155.0604 112.3514
PWK/PhJ both 186.1636 9.762 205.3989 166.9284




  GWAS USING LINEAR MIXED MODELS